Ambrisentan

Type: Keyphrase
Name: Ambrisentan
First reported Apr 17 2014 - Updated Apr 17 2014 - 1 reports

Lung Diseases and Conditions: New Data from Department of Cardiology Illuminate Findings in Pulmonary Hypertension

Today's Medical & Research NewsLung Diseases and Conditions2014 APR 17 -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Data detailed on Lung Diseases and Conditions have been presented. According to news reporting from Foggia, Italy, ... [Published NewsRX - Apr 17 2014]
First reported Apr 11 2014 - Updated Apr 11 2014 - 1 reports

Management of idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis is a life-limiting, incurable condition. Recent guidance from NICE identifies priorities of care for this group of patientsIn this article… Definition of idiopathic pulmonary fibrosis Priorities for managing patients with ... [Published Nursing Times - Apr 11 2014]
First reported Apr 08 2014 - Updated Apr 08 2014 - 1 reports

Methods of treating mixed dyslipidemia

Description of the InventionBACKGROUNDCardiovascular disease is one of the leading causes of death in the United States and most European countries. It is estimated that over 70 million people in the United States alone suffer from a cardiovascular disease ... [Published PharmCast - Apr 08 2014]
First reported Mar 19 2014 - Updated Mar 19 2014 - 1 reports

Contrary to popular belief, side-effect reports on new meds keep a steady pace, study finds

AdverseEvents CEO Brian Overstreet--Courtesy of AdverseEventsSide-effect reports to the FDA are a contentious subject. Despite a series of efforts to improve adverse-event reporting, numbers from the agency's database tend to be quoted with an accompanying ... [Published FiercePharma - Mar 19 2014]
First reported Mar 19 2014 - Updated Mar 19 2014 - 1 reports

Bone Metabolism Biomarkers Predict Prostate Cancer Survival

Levels of biomarkers linked to bone metabolism (bone formation and resorption) are indicative of survival in patients with castration-resistant prostate cancer (CRPC), and identify a small group of patients who can benefit from treatment with the investigational ... [Published Lab Medica - Mar 19 2014]

Quotes

...According to news reporting from Foggia, Italy, by NewsRx journalists, research stated, "Idiopathic pulmonary fibrosis (IPF) is a chronic condition of unknown etiology with deteriorating respiratory function leading to respiratory failure. Corticosteroids, alone or in combination with immunosuppressive drugs such as azathioprine, colchicine, and cyclophosphamide, have been used with limited success."
...as gospel," said Overstreet, who's also CEO of AdverseEvents, a company that analyzes FAERS for payers, healthcare systems and pharma companies. "It's been accepted as dogma that the data can't be used."
"Atrasentan kept coming up short in randomized trials because the drug only works for a small group," said Dr. Lara. "Because certain drugs only succeed in a fraction of patients, drug makers need to factor in these bone metabolism markers in their trial design. They need to target the patients most likely to benefit. I think the days of doing empirical studies on all comers should end. You need to have an appropriate database of patients and perform a rigorous analysis to find the subset who will benefit from an investigational drug."

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Lung Diseases and Conditions: New Data from Dep... [Published NewsRX - Apr 17 2014]
Management of idiopathic pulmonary fibrosis [Published Nursing Times - Apr 11 2014]
Methods of treating mixed dyslipidemia [Published PharmCast - Apr 08 2014]
Human medicines European public assessment repo... [Published Pending EC decisions and European Public Assess ... - Mar 27 2014]
Contrary to popular belief, side-effect reports... [Published FiercePharma - Mar 19 2014]
Bone Metabolism Biomarkers Predict Prostate Can... [Published Lab Medica - Mar 19 2014]
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Human medicines European public assessment repo... [Published Pending EC decisions and European Public Assess ... - Mar 27 2014]
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