Angiotensin Converting Enzyme

Type: Keyphrase
Name: Angiotensin Converting Enzyme
First reported 22 hours ago - Updated 11 hours ago - 1 reports

New drug '20% more effective than ACE inhibitors' for treating heart failure

Ratings require JavaScript to be enabled. For treating patients with chronic heart failure, ACE inhibitors are usually the first port of call. But a new study claims an experimental drug called LCZ696 performs around 20% better than ACE inhibitors ... [Published Medical News Today - 22 hours ago]
First reported Aug 30 2014 - Updated Aug 31 2014 - 1 reports

Novartis' New Heart Drug Reduces Cardiovascular Deaths - Update

Swiss drug maker Novartis AG (NVS: Quote) said Saturday its investigational heart failure drug LCZ696 was found to be superior to enalapril on key endpoints in a heart failure study.In the Paradigm-HF trial, LCZ696 cut cardiovascular deaths by 20 percent ... [Published RTTNews.com - Aug 30 2014]
First reported Aug 30 2014 - Updated Aug 30 2014 - 1 reports

Angiotensin–Neprilysin Inhibition versus Enalapril in Heart Failure

Angiotensin-converting–enzyme (ACE) inhibitors have been the cornerstone of the treatment for heart failure and a reduced ejection fraction for nearly 25 years, since enalapril was shown to reduce the risk of death in two trials. Long-term treatment with ... [Published The New England Journal of Medicine: Cardiology - Aug 30 2014]
First reported Aug 25 2014 - Updated Aug 25 2014 - 1 reports

Biolab offers CVD panel testing for genetic mutations

, the exclusive Biomnis dealer in the Kingdom, offers a Cardiovascular Disease CVD panel test for genetic mutations associated with blood clotting in the body, which is considered one of the latest tests in the diagnosis of heart disease.CVD Panel testing ... [Published Albawaba - Aug 25 2014]
First reported Aug 20 2014 - Updated Aug 20 2014 - 1 reports

US pharmacist-led intervention improves adherence but not outcomes

By News teamA pharmacist-led intervention for patients with acute coronary syndrome led to improved adherence to cardiac medicines during the year after discharge in a study reported from the US. However, there was no improvement in the proportion of ... [Published Pharmaceutical Journal - Aug 20 2014]
First reported Aug 19 2014 - Updated Aug 19 2014 - 1 reports

BNF updates advice on dual blockade and ivabradine use

Source: Zayacskz / Dreamstime.comPatients taking ivabradine should be monitored for bradycardia (a resting heart rate below 60 beats per minute)Warnings on “dual blockade” — the concomitant use of drugs that affect the renin-angiotensin system (RAS) — ... [Published Pharmaceutical Journal - Aug 19 2014]
First reported Aug 18 2014 - Updated Aug 18 2014 - 1 reports

Prescription meds increase risk of falls

Elderly people taking commonly prescribed medicines are at a higher risk of experiencing falls, according to a new study.The research, published in the European Journal of Public Health , found that 11 of the top 20 most commonly prescribed medications ... [Published 6minutes.net.au - Aug 18 2014]
First reported Aug 15 2014 - Updated Aug 15 2014 - 1 reports

Do Your ACE Inhibitor Meds Make You Cough?

Many people with diabetes have problems with high blood pressure, and angiotensin-converting enzyme (ACE) inhibitors are ideal solutions, says the American Diabetes Association (ADA).One of the benefits of ACE inhibitors is that they can reduce blood ... [Published DailyMe.Com - Aug 15 2014]
First reported Aug 14 2014 - Updated Aug 14 2014 - 1 reports

Prescription meds raise risk of falls in elderly: study

Elderly people taking commonly prescribed medicines are at a higher risk of experiencing falls, according to a new study.The research, published in the European Journal of Public Health , found that 11 of the top 20 most commonly prescribed medications ... [Published Pharmacy News - Aug 14 2014]
First reported Aug 06 2014 - Updated Aug 06 2014 - 1 reports

Study Modification: Angiotensin-converting enzyme activity

AUTHOR: Chung CMSTUDY DATE: January 12, 2010TITLE: A genome-wide association study identifies new loci for ACE activity: potential implications for response to ACE inhibitor. ... [Published National Human Genome Research Institute - Aug 06 2014]
First reported Aug 06 2014 - Updated Aug 06 2014 - 1 reports

Crystal structure of the N-terminal domain of angiotensin converting enzyme and uses thereof

The present invention relates to a crystal. In particular the present invention relates to a crystal of the N-domain of ACE protein. The present invention also relates to methods, processes, domain specific modulators, pharmaceutical compositions and ... [Published Free Patents Online - Aug 06 2014]
First reported Aug 04 2014 - Updated Aug 04 2014 - 1 reports

Stroke: Reports Outline Stroke Study Findings from Nanjing Medical University [The expression of angiotensin-converting enzyme 2-angiotensin-(1-7)-Mas receptor axis are upregulat

By a News Reporter-Staff News Editor at Life Science Weekly -- Researchers detail new data in Stroke. According to news reporting originating from Nanjing, People's Republic of China, by NewsRx correspondents, research stated, "There is now unequivocal ... [Published NewsRX - Aug 04 2014]

Quotes

The researchers concluded that "LCZ696 was superior to enalapril in reducing the risks of death, and of hospitalisation for heart failure."
Moreover, a study published in the Journal of Agricultural and Food Chemistry in June 2013 found that a compound present in asparagus, 2 "-hydroxynicotianamine, could inhibit angiotensin-converting enzyme activity in the kidneys, thus "preventing hypertension and preserving renal function." (4)"
"The purpose of using a drug like this isn't to make people feel better," says Dr. Packer. "The major benefit is that the natural course of the disease is changed. I don't think it changes the natural history of heart failure - I know it does."
"By demonstrating a very significant reduction in cardiovascular deaths while improving quality of life, Novartis' new heart failure medicine, LCZ696, represents one of the most important cardiology advances of the last decade" said David Epstein, division head, Novartis Pharmaceuticals

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All (67) | News (57) | Reports (0) | Blogs (10) | Audio/Video (0) | Fact Sheets (0) | Press Releases (0)
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Novartis' Game Changer: When Failure Turns To S... [Published Forbes.com - 2 hours ago]
Heart failure drug could 'cut deaths by a fifth' [Published Cotswold Journal - 21 hours ago]
Three foods that can treat kidney disease and b... [Published Natural News - 21 hours ago]
New drug '20% more effective than ACE inhibitor... [Published Medical News Today - 22 hours ago]
Novartis' New Heart Drug Reduces Cardiovascular... [Published RTTNews.com - Aug 30 2014]
MUSC researchers part of breakthrough drug for ... [Published Charleston Post and Courier - Aug 30 2014]
Novartis' new heart failure medicine LCZ696 cut... [Published Scottrade - Aug 30 2014]
Angiotensin–Neprilysin Inhibition versus Enalap... [Published The New England Journal of Medicine: Cardiology - Aug 30 2014]
Risk Factors for Developing Hyponatremia in Thy... [Published Plosone.org - Aug 29 2014]
Kidney Fibrosis Treatment Market Segment Foreca... [Published MyNewsDesk - Aug 28 2014]
Agents for Atrial Fibrillation Prevention After... [Published General Medicine eJournal - Aug 28 2014]
Pulmonary Hypertension With COLD and Pulmonary ... [Published General Medicine eJournal - Aug 28 2014]
Investigators at Institute for Molecular Biotec... [Published HispanicBusiness.com - Aug 28 2014]
Antihypertensive Medication Classes Used among ... [Published Plosone.org - Aug 25 2014]
Biolab offers CVD panel testing for genetic mut... [Published Albawaba - Aug 25 2014]
Pharmacists reminded to look out for risky comb... [Published Pharmaceutical Journal - Aug 22 2014]
Apotex Inc. v. UCB, Inc. (Fed. Cir. 2014) [Published JD Supra - Aug 20 2014]
US pharmacist-led intervention improves adheren... [Published Pharmaceutical Journal - Aug 20 2014]
Can Statins Help Treat Ebola? [Published AllAfrica.com - Aug 20 2014]
Biomarkers in Heart Failure: A Call to Arms [Published Theheart.org - Aug 19 2014]
BNF updates advice on dual blockade and ivabrad... [Published Pharmaceutical Journal - Aug 19 2014]
Pfizer Updates on Lyrica Studies Conducted in C... [Published Individual.com - Aug 19 2014]
Early sign of kidney disease often ignored, stu... [Published Milwaukee Times - Aug 18 2014]
Statin drugs may help fight Ebola [Published Examiner.com - Aug 18 2014]
Could statins help treat Ebola? [Published AMERICAblog News| A great nation deserves the t ... - Aug 18 2014]
The Emerging Role of Epigenetics in Cardiovascu... [Published Theheart.org - Aug 18 2014]
Prescription meds increase risk of falls [Published 6minutes.net.au - Aug 18 2014]
Can statins help treat Ebola? [Published H5N1 - Aug 16 2014]
Do Your ACE Inhibitor Meds Make You Cough? [Published DailyMe.Com - Aug 15 2014]
Prescription meds raise risk of falls in elderl... [Published Pharmacy News - Aug 14 2014]
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sort by: Date | Relevance
Angiotensin–Neprilysin Inhibition versus Enalap... [Published The New England Journal of Medicine: Cardiology - Aug 30 2014]
Angiotensin-converting–enzyme (ACE) inhibitors have been the cornerstone of the treatment for heart failure and a reduced ejection fraction for nearly 25 years, since enalapril was shown to reduce the risk of death in two trials. Long-term treatment with ...
Could statins help treat Ebola? [Published AMERICAblog News| A great nation deserves the t ... - Aug 18 2014]
In an article in the New York Times , two physicians propose using drugs that are currently available to treat Ebola. Ebola causes a derangement in endothelial cells (cells lining blood vessels), and this can lead to decreased ability of the patient’s ...
Can statins help treat Ebola? [Published H5N1 - Aug 16 2014]
Via The New York Times, an op-ed by two American professors of medicine: Can Statins Help Treat Ebola? Excerpt:This week, the World Health Organization endorsed the use of experimental drugs in the fight against the Ebola epidemic in West Africa. That ...
Symplmed Completes Ownership of Perindopril Fra... [Published Business Wire Technology News - Jul 18 2014]
CINCINNATI--(BUSINESS WIRE)--Symplmed announced today that it has acquired U.S. rights to ACEON® (perindopril erbumine tablets), an angiotensin converting enzyme (ACE) inhibitor approved to treat patients with high blood pressure (hypertension) and reduce ...
Symplmed Completes Ownership of Perindopril Fra... [Published Business Wire Health News - Jul 18 2014]
CINCINNATI--(BUSINESS WIRE)--Symplmed announced today that it has acquired U.S. rights to ACEON® (perindopril erbumine tablets), an angiotensin converting enzyme (ACE) inhibitor approved to treat patients with high blood pressure (hypertension) and reduce ...
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