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Publication: Bio Techniques

First reported May 18 2013 - Updated May 18 2013 - 1 reports

No Consensus on Incidental Findings

A leading medical organization’s new policy states that patients should be informed of incidental genetic findings regardless of their desire to know. Not all experts agree. Find out why…As exemplified this week by Angelina Jolie’s soul-baring op-ed in ... [Published Bio Techniques - May 18 2013]

Entities: George Annas, Informed Consent, Susan Wolf, Genomics

First reported May 15 2013 - Updated May 16 2013 - 1 reports

Embryonic Stem Cells Get Personal

For the first time, scientists have successfully created human embryonic stem cells using somatic cell nuclear transfer. Find out how...Scientists have created viable human embryonic stem cells (ESCs) by transferring the nucleus of a skin fibroblast cell ... [Published Bio Techniques - May 15 2013]

Entities: Embryonic Stem Cell, Nucleus, Donor

First reported May 15 2013 - Updated May 15 2013 - 1 reports

Is Noncoding DNA Required for Complex Life?

Noncoding DNA makes up only 3% of the carnivorous bladderwort plant genome. So does that prove that noncoding DNA is unnecessary for complex life? Find out...Since scientists first discovered that more than 95% of the human genome was made up of non-coding ... [Published Bio Techniques - May 15 2013]

Entities: DNA, Genome, Utricularia, Natural Selection, Non-coding DNA

First reported May 13 2013 - Updated May 13 2013 - 1 reports

Building Stronger Bones in a Dish

Bone substitutes engineered from human-induced pluripotent stem cells could lead to new bone repair treatments. Could lab-grown bone one day find a place under your skin?Most of us have had to deal with a broken bone or two in our day. Usually these ... [Published Bio Techniques - May 13 2013]

Entities: Grafting, pluripotent, Tissue Engineering, Phenotype

First reported May 10 2013 - Updated May 10 2013 - 1 reports

Profile of Bruce Beutler

Bruce Beutler's research into the basis of innate immunity and his elucidation of the functional roles of many different proteins involved in the immune response caught our attention. Curious to know more, BioTechniques contacted him to find out about ... [Published Bio Techniques - May 10 2013]

Entities: Bruce A Beutler, Receptor, immune response, Lipase

First reported May 10 2013 - Updated May 10 2013 - 1 reports

A convenient and efficient purification method for chemically labeled oligonucleotides

1WCU Department of Biophysics and Chemical Biology, Seoul National University, Korea2Department of Chemistry, Seoul National University, Korea3EMBL, Structural and Computational Biology Unit, Heidelberg, Germany4Biomedical Research Institute, Korea Institute ... [Published Bio Techniques - May 10 2013]

Entities: DNA, Hydrophobic, Chromatography, Aqueous, Chemical

First reported May 10 2013 - Updated May 10 2013 - 1 reports

The chemist in the kitchen

“Food is fuel. You get picky about what you put in the tank, your engine is gonna die. Now shut up and eat your garbage.” —Django the rat, to his son Remy, in Pixar's RatatouilleIf you haven't seen Ratatouille, put down this journal, fire up iTunes, and ... [Published Bio Techniques - May 10 2013]

Entities: Metabolite, Nutrition, Nutritional Genomics, Nutrigenetics

First reported May 10 2013 - Updated May 10 2013 - 1 reports

Citations

The menu of site-directed mutagenesis offerings just gained a little flavor—MISO (multichange isothermal) mutagenesis. The technique is described in the recently launched journal ACS Synthetic Biology. It was developed out of the frustrations authors ... [Published Bio Techniques - May 10 2013]

Entities: Mutagenesis, Plasmid, Isothermal, Nanoparticle, Polymerase Chain Reaction

First reported May 10 2013 - Updated May 10 2013 - 1 reports

The Write Way

Several year ago when I joined BioTechniques as editor-in-chief, we launched two main editorial initiatives. First, publish techniques that would immediately enhance the research efforts of a wide range of scientists. Second, assist authors in communicating ... [Published Bio Techniques - May 10 2013]

Entities: Distillation, Speculations, Interaction

First reported May 10 2013 - Updated May 10 2013 - 1 reports

Primer design

This month's question from the Molecular Biology Forums (online at molecularbiology.forums.biotechniques.com) comes from the “Real-Time qPCR/qRT-PCR Methods” section. Entries have been edited for concision and clarity. Mentions of specific products and ... [Published Bio Techniques - May 10 2013]

Entities: Annealing, Nucleotide, Polymerase

First reported May 10 2013 - Updated May 10 2013 - 2 reports

BioSpotlight

Protein microarrays are an increasingly popular tool for detecting proteins and antibodies as well as probing their interactions. Investigators usually detect interactions on protein arrays using fluorescently labeled secondary antibodies followed by ... [Published Bio Techniques - May 10 2013]

Entities: agonist, thrombocyte, Antibody, Protein

First reported May 10 2013 - Updated May 10 2013 - 1 reports

Quantifying antibody binding on protein microarrays using microarray nonlinear calibration

Protein microarrays are useful tools for simultaneously assessing antibody reactivity against a large number of targets using only a minute amount of sample. This multiplex capability makes microarrays attractive for evaluating antibody specificity and ... [Published Bio Techniques - May 10 2013]

Entities: Antibody, Protein, Calibration, Plasmid

Quotes

..."I think we chose the right strain of Wolbachia and the right mosquito species to try it in," said Xi. "I chose this strain because the first step is to start with something easier to control and to manipulate, then we'll move to a more difficult one."

Malaria-Proof Mosquitoes [Published Bio Techniques - May 10 2013]

"It's paradoxical that we don't yet have this," Harvard geneticist George Church says on the project's fundraising page. "Biology is very energy efficient and energy packets are more dense than batteries. Even a weakly glowing flower would be a great icon."

Glowing Plants: Coming to a Garden near You [Published Bio Techniques - May 09 2013]

...They reasoned that dPCR does seem to have legs as a technique and that certain dogmatic ideas about the process are already becoming set in stone. "We are very much trying to, at an early stage, get people thinking about the benefits of dPCR, while still remembering there are some limitations, and most importantly, that you need to prove to yourself that the technique is working well enough, rather than just assuming it's fine" says Huggett

MIQE qPCR Guidelines, Three Years Later [Published Bio Techniques - May 01 2013]

"Our technique provides an unbiased picture of the proteins that cells secrete to communicate with each other upon activation" said Felix Meissner, lead author of a paper in the April 26 issue of Science that describes the new method (1)

Decoding Covert Cell Signals [Published Bio Techniques - Apr 29 2013]

More Content

sort by: Date \| Relevance
No Consensus on Incidental Findings [Published Bio Techniques - May 18 2013]
Embryonic Stem Cells Get Personal [Published Bio Techniques - May 15 2013]
Is Noncoding DNA Required for Complex Life? [Published Bio Techniques - May 15 2013]
Building Stronger Bones in a Dish [Published Bio Techniques - May 13 2013]
BioSpotlight [Published Bio Techniques - May 10 2013]
The Write Way [Published Bio Techniques - May 10 2013]
Citations [Published Bio Techniques - May 10 2013]
Profile of Bruce Beutler [Published Bio Techniques - May 10 2013]
The chemist in the kitchen [Published Bio Techniques - May 10 2013]
Primer design [Published Bio Techniques - May 10 2013]
Quantifying antibody binding on protein microar... [Published Bio Techniques - May 10 2013]
Pairwise agonist scanning-flow cytometry (PAS-F... [Published Bio Techniques - May 10 2013]
A convenient and efficient purification method ... [Published Bio Techniques - May 10 2013]
Lane-by-lane sequencing using Illumina's Genome... [Published Bio Techniques - May 10 2013]
Malaria-Proof Mosquitoes [Published Bio Techniques - May 10 2013]
Glowing Plants: Coming to a Garden near You [Published Bio Techniques - May 09 2013]
Genital Herpes under Surveillance [Published Bio Techniques - May 09 2013]
Liquid-Handling Face-Off [Published Bio Techniques - May 07 2013]
Expression analysis of rare cellular subsets: d... [Published Bio Techniques - May 04 2013]
More Precise, Cheaper GMO Analysis via dPCR [Published Bio Techniques - May 03 2013]
New Subtypes of Endometrial Cancer [Published Bio Techniques - May 02 2013]
HIV Technician Faked PCR Results [Published Bio Techniques - May 01 2013]
MIQE qPCR Guidelines, Three Years Later [Published Bio Techniques - May 01 2013]
Decoding Covert Cell Signals [Published Bio Techniques - Apr 29 2013]
Quantum Physicists Get Dirty [Published Bio Techniques - Apr 25 2013]
New Deal for Researcher Found Guilty of Misconduct [Published Bio Techniques - Apr 22 2013]
Once Thought Extinct, Coelacanth Now Has Genome... [Published Bio Techniques - Apr 18 2013]
History Lessons [Published Bio Techniques - Apr 12 2013]
Optimized Blocking Of Porous Nitrocellulose Fil... [Published Bio Techniques - Apr 12 2013]
A cell-free assay to determine the stoichiometr... [Published Bio Techniques - Apr 12 2013]