BRCA1

Type: Keyphrase
Name: BRCA1
First reported 10 hours ago - Updated 4 hours ago - 2 reports

Researchers to study mechanisms of hard-to-solve, hereditary breast cancer to find treatment option

Mutations in the BRCA1 gene can lead to breast cancer, which can be detected using mammography.ROANOKE, Va., July 29, 2014 – Deborah Kelly and Zhi Sheng , assistant professors at the Virginia Tech Carilion Research Institute, recently received a grant ... [Published Virginia Tech - 4 hours ago]
First reported 17 hours ago - Updated 17 hours ago - 1 reports

PARP inhibitor possible addition to pancreatic cancer treatment regimen

the Cancer Therapy Advisor take:Of all the solid tumors, locally advanced pancreatic cancer has the lowest 5-year survival rate, at 4%. Since tumors usually involve vital blood vessels, patients with this disease are seldom candidates for surgery.Although ... [Published Chemotherapy Advisor - 17 hours ago]
First reported 17 hours ago - Updated 17 hours ago - 1 reports

Coregulation of FANCA and BRCA1 in human cells

Fanconi anemia (FA) is a genetically heterogeneous syndrome associated with increased cancer predisposition. The underlying genes govern the FA pathway which functions to protect the genome during the S-phase of the cell cycle.While upregulation of FA ... [Published 7thSpace - 17 hours ago]
First reported Jul 25 2014 - Updated Jul 25 2014 - 1 reports

Duo bonded by brave breast decision

Yasmin Grigaliunas and Elise Worthington have been nominated for medals for their work raising awareness of genetic cancers, and the BRCA1 gene. Picture: Tara Croser Source: News Limited FACED with the prospect of a cancer diagnosis because of an extensive ... [Published Brisbane Courier-Mail - Jul 25 2014]
First reported Jul 24 2014 - Updated Jul 24 2014 - 2 reports

The Genetics Of Mental Health

Jane C. Hu presents new research that found “autism is 55 percent heritable,” which is higher than previously thought:The most surprising finding in this study is that the genetic risk for autism lies mostly in variations of common genes, and not specific ... [Published Atlantic Monthly - Jul 24 2014]
First reported Jul 23 2014 - Updated Jul 23 2014 - 1 reports

Women With BRCA Mutations Report Significant Side Effects Following Risk-Reducing Salpingo-Oophorectomy

By The ASCO PostJuly 25, 2014, Volume 5, Issue 12Figures:Susan Domchek, MDOur work highlights the need for novel strategies to prevent breast and ovarian cancer. Despite the efficacy of oophorectomy, given the negative impact [on quality of life], we ... [Published The ASCO Post - Jul 23 2014]
First reported Jul 23 2014 - Updated Jul 23 2014 - 1 reports

Adding MRI Beneficial for Screening High-Risk Breast Cancer

An annual screening for breast cancer using a combination of magnetic resonance imaging (MRI) and mammography could be an effective program for high-risk women, particularly those who are known BRCA mutation carriers. These are the results of the Ontario ... [Published Diagnostic Imaging - Jul 23 2014]
First reported Jul 23 2014 - Updated Jul 23 2014 - 1 reports

Long-term prospective clinical follow-up after BRCA1/2 presymptomatic testing: BRCA2 risks higher than in adjusted retrospective studies

AbstractBackground The risks of breast cancer associated with BRCA1 and BRCA2 mutations vary considerably across studies but few have assessed prospective risks, which are likely to provide more reliablerisk estimates for women undergoing presymptomatic ... [Published Journal of Medical Genetics - Jul 23 2014]
Entities: BRCA2, BRCA1, Breast Cancer, Risk
First reported Jul 22 2014 - Updated Jul 22 2014 - 1 reports

Forum Post: Brca 1 positive at 22!

For people who have, or might have, the BRCA1 or BRCA2 gene, whether they have cancer or not. Discuss your worries about the increased risk of breast and ovarian cancer, and share experiences of things like genetic testing or risk-reducing surgery.Brca ... [Published Macmillan Cancer Support - Jul 22 2014]
First reported Jul 22 2014 - Updated Jul 22 2014 - 1 reports

Making Health Care System More Efficient Subject Of Forum

HARTFORD -- A forum on health care Monday had a "best of times, worst of times" feel.Some members of the panel convened by U.S. Rep. John Larson spoke of the tremendous explosion of knowledge and innovation that is dramatically remaking the health care ... [Published Hartford Courant - Jul 22 2014]
First reported Jul 22 2014 - Updated Jul 22 2014 - 1 reports

Cancer Syndromes and Family History

Dr. Shoba KankipatiMajority of Cancer is sporadic, which means that it occurs without known family history. However there are specific cancer syndromes that can occur in multiple family members at an early age and can be related to a genetic mutation. ... [Published The Valley Sentinel - Jul 22 2014]
First reported Jun 30 2014 - Updated Jun 30 2014 - 4 reports

Simple Blood Test Could Predict Breast Cancer Years In Advance

By In an ongoing project at University College London (UCL), researchers may have identified an epigenetic signature in the blood of some women that could be an accurate predictor of certain types of breast cancer.The researchers have focused on looking ... [Published Medical Design Online - Jun 30 2014]

Quotes

The study's lead researcher, Dr. Todd Tuttle, said, "We found fairly convincing evidence that there really is no meaningful long-term survival benefit for the vast majority of women with breast cancer by having their opposite breast removed."
...strategic action that will further enhance our long-term growth prospects," said Richard A Gonzalez, chairman and chief executive officer, AbbVie. "Last month, we raised our 2014 earnings-per-share guidance, reflecting strong underlying business performance. We continue to expect positive trends for the second half of the year, as well as additional progress from our pipeline, including the expected U S approval of our interferon-free HCV combination."
...) "Just 10 years ago, the cost of sequencing the BRCA1 gene was over $4,000,'' he said. "We can easily sequence 400 genes for about the same price and at much deeper coverage."
...Tuli, MD, PhD, a radiation oncologist in the Department of Radiation Oncology and a member of the Samuel Oschin Comprehensive Cancer Institute. "Coupled with this research treatment, we are also looking to identify patient biomarkers, or molecular signatures, that may provide clues to how, and why, some patients respond better than others."

More Content

All (273) | News (230) | Reports (0) | Blogs (43) | Audio/Video (0) | Fact Sheets (0) | Press Releases (0)
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Double mastectomies offer almost no survival be... [Published Natural News - 3 hours ago]
Researchers to study mechanisms of hard-to-solv... [Published Virginia Tech - 4 hours ago]
[News] Epigenetic test for breast cancer [Published Lancet Oncology - 10 hours ago]
PARP inhibitor possible addition to pancreatic ... [Published Chemotherapy Advisor - 17 hours ago]
Coregulation of FANCA and BRCA1 in human cells [Published 7thSpace - 17 hours ago]
Why early detection is key in breast cancer pre... [Published Nigeria Daily Independent - Jul 27 2014]
Duo bonded by brave breast decision [Published Brisbane Courier-Mail - Jul 25 2014]
AbbVie Reports Second-Quarter 2014 Financial Re... [Published Scottrade - Jul 25 2014]
The Genetics Of Mental Health [Published Atlantic Monthly - Jul 24 2014]
The Genetics Of Mental Health [Published The Daily Dish | By Andrew Sullivan - Jul 24 2014]
Women With BRCA Mutations Report Significant Si... [Published The ASCO Post - Jul 23 2014]
Genes That Influence Puberty Identified; May Me... [Published Medical Daily - Jul 23 2014]
Adding MRI Beneficial for Screening High-Risk B... [Published Diagnostic Imaging - Jul 23 2014]
Health: The facts about breast cancer gene testing [Published Body And Soul - Jul 23 2014]
Long-term prospective clinical follow-up after ... [Published Journal of Medical Genetics - Jul 23 2014]
Forum Post: Brca 1 positive at 22! [Published Macmillan Cancer Support - Jul 22 2014]
Making Health Care System More Efficient Subjec... [Published Hartford Courant - Jul 22 2014]
Patent-Eligible Subject Matter in the United St... [Published JD Supra - Jul 22 2014]
Study: U.S. SC rulings pose challenge to some i... [Published The Southeast Texas Record - Jul 22 2014]
Unique study focuses on combined treatment appr... [Published EurekAlert! - Jul 22 2014]
New genetic loci associated with breast cancer ... [Published Ecancer Medicalscience - Jul 22 2014]
Cancer Syndromes and Family History [Published The Valley Sentinel - Jul 22 2014]
How a Celebrity's Breast Health Disclosure Matters [Published Yahoo! News - Jul 21 2014]
Personalized prostate cancer screening among me... [Published BMC - Jul 21 2014]
Autism Linked to Common Genes [Published Slate Magazine - Jul 21 2014]
Most Women Who Have Double Mastectomy Don’t Nee... [Published Epoch Times - Jul 21 2014]
Fact-based film on cancer breakthrough to premi... [Published Madison Eagle - Jul 19 2014]
The Sitdown: Kim Metcalfe, PR exec opts for dou... [Published Chicago Sun-Times - Jul 19 2014]
Laboratory Corporation of America Holdings' (LH... [Published Seeking Alpha - Jul 18 2014]
Absence of BRCA/FMR1 Correlations in Women with... [Published Plosone.org - Jul 18 2014]
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sort by: Date | Relevance
The Genetics Of Mental Health [Published The Daily Dish | By Andrew Sullivan - Jul 24 2014]
Jane C. Hu presents new research that found “autism is 55 percent heritable,” which is higher than previously thought: The most surprising finding in this study is that the genetic risk for autism lies mostly in variations of common genes, and not ...
Hobby Lobby's Not Alone: Here are 4 of the High... [Published MoJo Articles | Mother Jones - Jul 03 2014]
On Monday, the Supreme Court ruled that most private companies can decline to cover their employees' contraception for religious reasons. This verdict is wildly controversial as a piece of legal reasoning—but its scientific logic is wanting, as well. ...
Breast cancer blood test in development would p... [Published National Post - Top Stories - Jun 27 2014]
A simple blood test which predicts a woman’s likelihood of suffering breast cancer is being developed by scientists. For the first time, researchers have identified a way of discovering whether a woman is at risk even if she has no genetic predisposition. ...
Patent Parameters [Published Patently BIOtech - Jun 24 2014]
Supreme Court Finds Naturally Occurring DNA to Be Patent Ineligible Last summer, the Supreme Court issued its decision in Association for Molecular Pathology v. Myriad Genetics, Inc., which concerned the patent eligibility of the BRCA1 and BRCA2 genes. ...
Patent Parameters [Published I Am Biotech - Jun 24 2014]
Supreme Court Finds Naturally Occurring DNA to Be Patent Ineligible Last summer, the Supreme Court issued its decision in Association for Molecular Pathology v. Myriad Genetics, Inc., which concerned the patent eligibility of the BRCA1 and BRCA2 genes. ...
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