BRCA1

Type: Keyphrase
Name: BRCA1
First reported 4 hours ago - Updated 4 hours ago - 1 reports

"Breast cancer gene" lawyers launch appeal to High court

Cancer advocates will appeal to the High Court to overturn a controversial decision that human genes can be controlled by private companies.Two weeks ago a full bench of the Federal Court . Late on Tuesday Maurice Blackburn lawyers launched an application ... [Published Brisbane Times - 4 hours ago]
First reported 6 hours ago - Updated 6 hours ago - 1 reports

Australian court finds human gene mutation to be patentable

A full panel of the Federal Court of Australia has upheld its earlier ruling that an isolated but naturally occurring nucleic acid, BRCA1, can be patented. ). The decision stands in contrast to the U.S. Supreme Court’s conclusion in Association for Molecular ... [Published Lexology - 6 hours ago]
First reported 20 hours ago - Updated 6 hours ago - 2 reports

Drug trial raises hope for BRCA carriers

TRIALS of a new anti breast cancer drug have raised hopes that women with a high chance of the disease have an alternative to preventive mastectomies.MELBOURNE researchers are studying if a medication used for osteoporosis can switch off the cancer-causing ... [Published Tasmania Mercury - 6 hours ago]
First reported 12 hours ago - Updated 8 hours ago - 2 reports

Ovarian Cancer Awareness Month

September is .For years, ovarian cancer was known as the “silent” cancer because it rarely produced any symptoms, and many women didn’t find out they had it until the cancer was very advanced. Now, however, doctors have identified specific signs that ... [Published Elkhart Truth - 8 hours ago]
First reported Sep 16 2014 - Updated Sep 16 2014 - 1 reports

Pathway Genomics Debuts BreastTrue High Risk Panel

Pathway Genomics Corp. reported it has launched BreastTrue High Risk Panel, a blood or saliva next-generation sequencing test with deletion/duplication analysis to detect mutations in seven high-risk breast cancer susceptibility genes, including BRCA1, ... [Published Individual.com - Sep 16 2014]
First reported Sep 15 2014 - Updated Sep 15 2014 - 5 reports

PALB2 Study: Researchers and Patients Must 'Pal' for Progress

By Judy E. Garber, MD, MPHSeptember 15, 2014, Volume 5, Issue 15The recent publication by Antoniou et al on risk of breast cancer in PALB2 carriers, 1 reviewed in this issue of The ASCO Post (page 47), is a contribution to the interesting history of the ... [Published The ASCO Post - Sep 15 2014]
First reported Sep 15 2014 - Updated Sep 15 2014 - 1 reports

'Angelina Jolie effect' credited for increase in cancer screenings

In her May 2013 op-ed piece for the NY Times , Angelina Jolie urged women to become informed and consider their options for taking preventative measures against cancer. The 39-year-old revealed that she had undergone a double mastectomy as a result of ... [Published Mother Nature Network - Sep 15 2014]
First reported Sep 15 2014 - Updated Sep 15 2014 - 1 reports

Management of the Patient With Postpartum Breast Cancer

1. Lambe M, Hsieh C, Trichopoulos D, et al. Transient increase in the risk of breast cancer after giving birth. N Engl J Med. 1994;331:5-9.2. Albrektsen G, Heuch I, Hansen S, Kvale G. Breast cancer risk by age at birth, time since birth and time intervals ... [Published Cancernetwork.com - Sep 15 2014]
First reported Sep 15 2014 - Updated Sep 15 2014 - 1 reports

2014 Lasker Award

By The ASCO PostSeptember 15, 2014, Volume 5, Issue 15Figures:Mary-Claire King, PhDThe Albert and Mary Lasker Foundation has announced Mary-Claire King, PhD, of the University of Washington, Seattle, will receive the 2014 Lasker~Koshland Special Achievement ... [Published The ASCO Post - Sep 15 2014]
First reported Sep 15 2014 - Updated Sep 15 2014 - 1 reports

'She must have a spine of steel'

This is the first of six finalists in the Bell Tea/Herald on Sunday Getting On With It search for special, ordinary people.Ta'aloga Crichton, an Auckland social worker and finalist in the Bell Tea getting on with it promotion. Photo / Fiona Goodall /Nominations ... [Published New Zealand Herald - Sep 15 2014]
First reported Sep 12 2014 - Updated Sep 12 2014 - 3 reports

Myriad Publishes myRisk Hereditary Cancer Study

In a new study published in the journal Cancer , the myRisk hereditary cancer test by Myriad Genetics Inc, Salt Lake City, was shown to improve the detection of cancer-causing mutations by 46% in patients with breast cancer.In the study, researchers at ... [Published Clinical Lab Products - Sep 12 2014]
First reported Sep 11 2014 - Updated Sep 12 2014 - 2 reports

Genetic Testing For BRCA Is A Personal Decision

Earlier this week, geneticist Mary-Claire King received a much-deserved Lasker Foundation award for contributions to medical science. Most famously, Dr. King led a research team that identified the first breast cancer risk-conferring gene, BRCA-1 . Those ... [Published Forbes.com - Sep 12 2014]

Quotes

"Rather, the court held that Myriad was entitled to a patent for an isolated nucleic acid that is artificial and 'leads to an economically useful result – the treatment of breast and ovarian cancer'" she said
...potentially inside my children, it gives us a lot of hope for what the future holds," said Ms Barter, who at 25 opted to have both breasts removed. "It might be five or ten years but it could potentially be for my daughter and that's something that is incredible. "Imagine one day when my daughter goes and has a gene testing and I can say to her `you don't have to worry, you can have an injection and it will be all fine'. "That's really amazing for a mum to think that." Dr Sheau Wen Lok, associate investigator of the research study, said as far as the research team is aware it's the first time this drug has been trialled in humans for this purpose. The research team previously discovered that a cell type - called "progenitor" cells - in normal breast tissue appears to be the culprit cell that leads to cancer in BRCA1 carriers. The current study will test if denosumab can turn off the progenitor cells. For BRCA carriers, risk reducing options including screening, prophylactic surgery or regularly taking a drug called tamoxifen, which has been shown to cause bothersome side effects for some women. "This drug we are working on does have its side effects but it has a different side effect profile to tamoxifen," Dr Lok said. "It possibly will offer another option for women." Researchers are looking for 30 women who are BRCA carriers who are planning to undergo a risk-reducing mastectomy or are prepared to undergo two breast biopsies."
"This work says that if you have a predisposition to getting cancer, wounding might enhance the chance that it will develop" says cell biologist Anthony Oro of Stanford University School of Medicine.”
...risk panel is a necessity to effectively serve physicians and their patients," said Jim Plante, Pathway Genomics' founder and CEO, in a release. "Our mission is clear and precise. We exist to provide the most accurate and comprehensive genetic tests to the medical community, and we will continue to innovate."

More Content

All (391) | News (340) | Reports (0) | Blogs (51) | Audio/Video (0) | Fact Sheets (0) | Press Releases (0)
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"Breast cancer gene" lawyers launch appeal to H... [Published Brisbane Times - 4 hours ago]
Australian court finds human gene mutation to b... [Published Lexology - 6 hours ago]
Drug trial raises hope for BRCA carriers [Published Tasmania Mercury - 6 hours ago]
Ovarian Cancer Awareness Month [Published Elkhart Truth - 8 hours ago]
So You Think You Can't … Stay Up-to-Date on Bre... [Published Healthywomen.org - 10 hours ago]
Fred Hutch (@HutchinsonCtr) Expert Available to... [Published Newswise - 12 hours ago]
Drug gives new breast cancer hope [Published Herald Sun - 20 hours ago]
Mammography False Alarms Linked with Later Tumo... [Published Mercola - Sep 16 2014]
Pathway Genomics Debuts BreastTrue High Risk Panel [Published Individual.com - Sep 16 2014]
PALB2 Study: Researchers and Patients Must 'Pal... [Published The ASCO Post - Sep 15 2014]
On a day when Apple sidesteps healthcare techno... [Published American Enterprise Institute - Sep 15 2014]
'Angelina Jolie effect' credited for increase i... [Published Mother Nature Network - Sep 15 2014]
Management of the Patient With Postpartum Breas... [Published Cancernetwork.com - Sep 15 2014]
News of Mutations in PALB2 Gene Raising Risk of... [Published The ASCO Post - Sep 15 2014]
Study Quantifies Risk of Hereditary Breast Canc... [Published The ASCO Post - Sep 15 2014]
'Offer breast cancer risk gene screening to eve... [Published BioNews - Sep 15 2014]
Rochester Hills breast cancer survivor joins lo... [Published Oakland Press - Sep 15 2014]
2014 Lasker Award [Published The ASCO Post - Sep 15 2014]
Go Under the Microscope to Find Out the Facts A... [Published 4 Traders - Sep 15 2014]
Here's Something You May Not Want To Know About... [Published Austin American Statesman - Sep 15 2014]
Here's Something You May Not Want To Know About... [Published Forbes.com - Sep 15 2014]
BeiGene Receives Clinical Milestone Payment for... [Published BioPortfolio - Sep 15 2014]
Journalist Amy Robach calls supports more breas... [Published Times Union - Sep 15 2014]
'She must have a spine of steel' [Published New Zealand Herald - Sep 15 2014]
Lumpectomy 'as effective as double mastectomy' [Published Nursing Times - Sep 14 2014]
ALDH1A1 Maintains Ovarian Cancer Stem Cell-Like... [Published Plosone.org - Sep 13 2014]
*The Queen of DNA* [Published Jerusalem Post - Sep 13 2014]
Angelina Jolie was hospitalized for anorexia an... [Published Examiner.com - Sep 13 2014]
The patent gene debate: who owns your genes? [Published Digital Journal - Sep 13 2014]
Myriad Publishes myRisk Hereditary Cancer Study [Published Clinical Lab Products - Sep 12 2014]
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Should All Women Be Screened for BRCA1 and BRCA2? [Published MedPageToday.com - medical news plus CME for ph ... - Sep 12 2014]
(MedPage Today) -- A 2014 Lasker Award winner is calling for all women to be screened for BRCA1 and BRCA2 mutations, following a study showing that many women carry such mutations despite having no family history of breast or ovarian cancer. ...
Australian Court Disagrees With US: Claim Genes... [Published Techdirt - Sep 09 2014]
Last year, the Supreme Court made an important ruling in the Myriad Genetics case, effectively saying that genes aren't patentable , even if you can separate them out from the rest of a strand of DNA. Myriad Genetics had isolated two key genes related ...
Australia: Myriad Gene Patents Look Good [Published Patent Law Blog (Patently-O) - Sep 07 2014]
Guest post by Ben McEniery.  McEniery is a Senior Lecturer in Law at the Queensland University of Technology and a Barrister who specialises in Intellectual Property Law matters. On Friday the Full Court of the Federal Court of Australia in  D’Arcy ...
Australian gene-patent case dismissed [Published nature.com blogs - Sep 05 2014]
Originally posted on - blogs by NPG staff An Australian federal court has thrown out an lawsuit challenging a patent on the cancer-associated gene BRCA1. The decision, issued 5 September, is the latest setback for patient advocates who argue that ...
The ‘Angelina Jolie Effect’: More Women Now Con... [Published Think Progress - Sep 05 2014]
This March 8, 2012 file photo shows actress Angelina Jolie at the Women in the World Summit in New York. Jolie says that she has had a preventive double mastectomy after learning she carried a gene that made it extremely likely she would get breast ...
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