Cell Lines

Type: Keyphrase
Name: Cell Lines
First reported 3 hours ago - Updated 2 hours ago - 1 reports

Scientists map the 'editing marks' on fly, worm, human genomes

The genome we inherited from our parents shapes many aspects of our lives. But in addition to our genome we have an epigenome that is set during development, but can be altered by our lifestyle habits and environmental exposuresand perhaps by those of ... [Published Bio-Medicine - 3 hours ago]
First reported 6 hours ago - Updated 6 hours ago - 1 reports

Pfizer buys into Cambridge life science innovation

Stem cell technology pioneer, DefiniGEN Ltd has joined the Pfizer-inspired European Bank for induced pluripotent stem cells (EBiSC) consortium.The consortium comprises 26 partners, and has been newly-formed with support from the Innovative Medicines Initiative ... [Published Business Weekly UK - 6 hours ago]
First reported 11 hours ago - Updated 11 hours ago - 1 reports

Malignancy-associated metabolic profiling of human glioma cell lines using 1H NMR spectroscopy

Ambiguity in malignant transformation of glioma has made prognostic diagnosis very challenging. Tumor malignant transformation is closely correlated with specific alterations of the metabolic profile.Exploration of the underlying metabolic alterations ... [Published 7thSpace - 11 hours ago]
First reported 19 hours ago - Updated 19 hours ago - 1 reports

MicroRNA-1246 enhances migration and invasion through CADM1 in hepatocellular carcinoma

Research articleZhao Sun , Changting Meng , Shihua Wang , Na Zhou , Mei Guan , Chunmei Bai , Shan Lu , Qin Han and Robert Chunhua ZhaoBMC Cancer 2014, 14 :616doi:10.1186/1471-2407-14-616Published: 27 August 2014Abstract (provisional) BackgroundThe aberrant ... [Published BMC - 19 hours ago]
First reported Aug 26 2014 - Updated Aug 26 2014 - 2 reports

Breakthrough antibacterial approach could resolve serious skin infections

( DOE/Los Alamos National Laboratory ) In several cases, scientists found an ionic liquid was more efficacious on a pathogenic biofilm than a standard bleach treatment and exhibited minimal cytotoxicity effects on human cell lines (unlike bleach). This ... [Published Infrosoft - Aug 26 2014]
First reported Aug 26 2014 - Updated Aug 26 2014 - 1 reports

Do Breast Cancer Cell Lines Provide a Relevant Model of the Patient Tumor Methylome?

by Leslie M. Cope, Mary Jo Fackler, Zoila Lopez-Bujanda, Antonio C. Wolff, Kala Visvanathan, Joe W. Gray, Saraswati Sukumar, Christopher B. UmbrichtIt is well documented that tumor cells undergo dramatic genetic and epigenetic changes during initial establishment ... [Published Plosone.org - Aug 26 2014]
First reported Aug 26 2014 - Updated Aug 26 2014 - 1 reports

Small Cell Lung Cancer Oncogene Discovered

the Cancer Therapy Advisor take:According to new findings published in the Journal of Thoracic Oncology, a somatic mutation at amino acid 918 in the rearranged during transfection (RET M918T) protein has been found in small cell lung cancer (SCLC).Researchers ... [Published Chemotherapy Advisor - Aug 26 2014]
First reported Aug 26 2014 - Updated Aug 26 2014 - 1 reports

Pharmaceutical composition with antibody that binds to heat shock protein 27(HSP270) and method for promoting wound healing

The present invention relates to a pharmaceutical composition for promoting angiogenesis, containing an antibody that specifically binds to heat shock protein (HSP) 27. In addition, the present invention relates to a pharmaceutical composition containing ... [Published Free Patents Online - Aug 26 2014]
First reported Aug 26 2014 - Updated Aug 26 2014 - 1 reports

Identification of structural features in chemicals associated with cancer drug response: a systematic data-driven analysis

Motivation: Analysis of relationships of drug structure to biological response is key to understanding off-target and unexpected drug effects, and for developing hypotheses on how to tailor drug therapies. New methods are required for integrated analyses ... [Published Bioinformatics - Aug 26 2014]
First reported Aug 26 2014 - Updated Aug 26 2014 - 1 reports

Cell lines for expressing enzyme useful in the preparation of amidated products

Cell lines are provided for expressing peptidylglycine alpha-amidating monooxygenase (PAM), or one of its two catalytic domains. High levels of enzyme expression are achieved while utilizing a non-animal source, low protein tissue culture medium. A robust ... [Published Free Patents Online - Aug 26 2014]
Entities: Cell Lines, Enzyme, AMIDE
First reported Aug 26 2014 - Updated Aug 26 2014 - 1 reports

Productivity augmenting protein factor, novel cell lines and uses thereof

The present invention provides a method for preparing a non-adenoviral target virus or target proteins utilizing a potent expression cell line having stably integrated into its genome a gene encoding a specific heterologous regulator protein. ... [Published Free Patents Online - Aug 26 2014]
First reported Aug 25 2014 - Updated Aug 25 2014 - 1 reports

An integrated analysis of the SOX2 microRNA response program in human pluripotent and nullipotent stem cell lines

Research articleSebastian F Vencken , Praveen Sethupathy , Gordon Blackshields , Cathy Spillane , Salah Elbaruni , Orla Sheils , Michael F Gallagher and John J O¿LearyBMC Genomics 2014, 15 :711doi:10.1186/1471-2164-15-711Published: 25 August 2014Abstract ... [Published BMC - Aug 25 2014]

Quotes

...Steve Bagshaw, Chief Executive Officer, FUJIFILM Diosynth Biotechnologies. He adds "Being similar to our existing bioreactors means they will fit seamlessly into our facilities. Having identical single-use operations on both sides of the Atlantic offers our customers flexibility and easy access to global markets. Combined with the expertise of our process development scientists to produce high-titer cell lines, our focus on single-use bioreactor technology for cell culture processes is world class."
"We went from two billion reads in research we published in 2011, to 20 billion reads today," says Celniker. "As a result, we found that the transcriptome is much more extensive and complex than previously thought. It has more long non-coding RNAs and more promoters."
...into prevention, diagnostics, and therapeutics for patients," said Kathy Hudson, Ph D , NIH deputy director for science, outreach, and policy. "The collective knowledge achieved through data sharing benefits researchers and patients alike, but it must be done carefully. The GDS policy outlines the responsibilities of investigators and institutions that are using the data and also encourages researchers to get consent from participants for future unspecified use of their genomic data."
"They're giving a drug to a whole person; they're not just giving it to their tumor cells," she said. "If you're going to alter the level of gene activation, you need to think about what could be the impact on other cells." This is where model organisms could be a big help, Elgin said

More Content

All (771) | News (663) | Reports (0) | Blogs (95) | Audio/Video (0) | Fact Sheets (4) | Press Releases (5)
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Liver ATF4 Upregulation Common to Many of the R... [Published Fight Aging! - 1 hour ago]
G Protein Beta 5 Is Targeted to D2-Dopamine Rec... [Published Plosone.org - 1 hour ago]
Scientists map the ‘editing marks’ on fly, worm... [Published WUSTL Science & Technology News - 2 hours ago]
Scientists Say New Antibacterial Approach Could... [Published PT Community - 2 hours ago]
Fujifilm Diosynth Biotechnologies Expands Cell ... [Published American Pharmaceutical Outsourcing - 2 hours ago]
Scientists map the 'editing marks' on fly, worm... [Published Bio-Medicine - 3 hours ago]
Expanding ENCODE [Published The Scientist - 3 hours ago]
The Jak2 Small Molecule Inhibitor, G6, Reduces ... [Published Plosone.org - 4 hours ago]
Encyclopedia of how genomes function gets much ... [Published EurekAlert! - 5 hours ago]
NIH Publishes Finalized Policy on Genomic Data ... [Published Genetic Engineering News - 5 hours ago]
Ionic Liquids Penetrate Skin, Bust Biofilms [Published Genetic Engineering News - 5 hours ago]
Encyclopedia of How Genomes Function Gets Much ... [Published Ein News - 6 hours ago]
Scientists map the 'editing marks' on fly, worm... [Published EurekAlert! - 6 hours ago]
Pfizer buys into Cambridge life science innovation [Published Business Weekly UK - 6 hours ago]
NIH issues finalized policy on genomic data sha... [Published Medical Xpress - 6 hours ago]
Exome Sequencing: Selective Characterisation of... [Published Pharmaceutical Technology - 8 hours ago]
Catalent and Minomic Collaborate to Bring New P... [Published Bio-Medicine - 11 hours ago]
Malignancy-associated metabolic profiling of hu... [Published 7thSpace - 11 hours ago]
MicroRNA-1246 enhances migration and invasion t... [Published BMC - 19 hours ago]
Cell Culture Market Worth $24,574 Million by 2018 [Published SBWire - Aug 26 2014]
Breakthrough antibacterial approach could resol... [Published Infrosoft - Aug 26 2014]
Biocontrol of Aspergillus Species on Peanut Ker... [Published Plosone.org - Aug 26 2014]
Breakthrough antibacterial approach could resol... [Published Bio-Medicine - Aug 26 2014]
Breakthrough antibacterial approach could resol... [Published EurekAlert! - Aug 26 2014]
Do Breast Cancer Cell Lines Provide a Relevant ... [Published Plosone.org - Aug 26 2014]
Small Cell Lung Cancer Oncogene Discovered [Published Chemotherapy Advisor - Aug 26 2014]
Peptidylarginine deiminase IV promotes the deve... [Published 7thSpace - Aug 26 2014]
Nurturing a new crop of nanomaterial specialists [Published The Chemical Institute of Canada - Aug 26 2014]
Pharmaceutical composition with antibody that b... [Published Free Patents Online - Aug 26 2014]
Identification of structural features in chemic... [Published Bioinformatics - Aug 26 2014]
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Blogs

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Liver ATF4 Upregulation Common to Many of the R... [Published Fight Aging! - 1 hour ago]
There are a score or more ways to reliably slow aging in mice , methods that include a few classes of drug, various single gene alterations, and calorie restriction . The most exceptional of these methods extends life by 60% or so, but most are in ...
Scientists map the ‘editing marks’ on fly, worm... [Published WUSTL Science & Technology News - 2 hours ago]
iStock and Creative CommonsD. melanogaster, the fruit fly, (top) has served for more than 100 years as a model for human biology, while the transparent worm C. elegans (bottom) is a comparative newcomer with a 40-year service record.   The genome ...
Anti-Choice Leaders Denounce The Ice Bucket Cha... [Published Slate - The XX Factor - Aug 22 2014]
The exploding popularity of the " ice bucket challenge "—where people record themselves dumping ice water over their heads to raise money to fight the neurogenerative disorder ALS—has inevitably  attracted people who want to hijack the issue for their ...
Skip RNA Purification and Still Receive Awesome... [Published Canadian BioTechnologist2.0 - Aug 20 2014]
Bio-Rad Laboratories announced the launch of new rapid cell lysis kits that allow researchers to obtain reverse transcription quantitative PCR (RT-qPCR) data directly from cultured cells without the need for a separate RNA purification step. Bio-Rad’s ...
Medical marijuana and the new herbalism, part 2... [Published ScienceBlogs : Combined Feed - Aug 18 2014]
About five weeks ago a month ago, I finally wrote the post I had been promising to write for months before about medical marijuana . At the time, I also promised that there would be follow-up posts. Like Dug the Dog seeing a squirrel, I kept running ...
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Press Releases

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Global Cell-based Assays (Reagents & Assay Kits... [Published GlobeNewswire: Acquisitions News - Jul 15 2014]
Independent Investigators Present Non-Clinical ... [Published GlobeNewswire: Acquisitions News - Apr 10 2014]
Celldex Therapeutics Establishes Preclinical Pr... [Published GlobeNewswire: Acquisitions News - Apr 07 2014]
Sigma® Life Science Launching Genetically-Modif... [Published PR Newswire - Jan 17 2014]
Absorption Systems Awarded Japanese Patent for ... [Published PR Newswire - Dec 17 2013]
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