DNA Methylation

Type: Keyphrase
Name: DNA Methylation
First reported Aug 18 2014 - Updated Aug 18 2014 - 1 reports

DNA methylation involved in Alzheimer’s disease

Related Biotechnology, Pharmaceutical and Healthcare NewsFirst large-scale study using EWAS to look at brain’s chromosomal […]Original Article: NEXT ARTICLE More From BioPortfolio on "DNA methylation involved in Alzheimer’s disease"Search BioPortfol ... [Published BioPortfolio - Aug 18 2014]
First reported Aug 18 2014 - Updated Aug 18 2014 - 1 reports

Targeted gene suppression by inducing de no DNA methylation in the gene promoter

Targeted gene silencing is an important approach in both drug development and basic research. However, the selection of a potent suppressor has become a significant hurdle to implementing maximal gene inhibition for this approach.We attempted to construct ... [Published 7thSpace - Aug 18 2014]
First reported Aug 18 2014 - Updated Aug 18 2014 - 3 reports

DNA methylation in brain 'linked to Alzheimer's disease'

Ratings require JavaScript to be enabled. DNA methylation - the biochemical alteration of the building blocks of DNA - can indicate whether DNA is biologically active within a region of the human genome. Now, researchers at Brigham and Women's ... [Published Medical News Today - Aug 18 2014]
First reported Aug 18 2014 - Updated Aug 18 2014 - 1 reports

The Emerging Role of Epigenetics in Cardiovascular Disease

Abbott, A. (2010) Project set to map marks on genome. Nature 463: 596–597.Abi Khalil, C., Roussel, R., Mohammedi, K., Danchin, N. and Marre, M. (2012) Cause-specific mortality in diabetes: recent changes in trend mortality. Eur J Prev Cardiol 19: 374 ... [Published Theheart.org - Aug 18 2014]
First reported Aug 18 2014 - Updated Aug 18 2014 - 1 reports

Epigenomic alterations in Alzheimer disease(Nature Neuroscience)

Specific epigenetic changes - a mechanism by which environmental factors may influence gene expression - in the brain of Alzheimer disease (AD) patients correlate with the pathological symptoms of the disease. These findings, reported in two independent ... [Published Natureasia.com - Aug 18 2014]
First reported Aug 17 2014 - Updated Aug 17 2014 - 1 reports

DNA Methylation Modifications Associated with Chronic Fatigue Syndrome

By Wilfred C. de Vega et al.AbstractChronic Fatigue Syndrome (CFS), also known as myalgic encephalomyelitis, is a complex multifactorial disease that is characterized by the persistent presence of fatigue and other particular symptoms for a minimum of ... [Published Pro Health Network - Aug 17 2014]
First reported Aug 15 2014 - Updated Aug 15 2014 - 1 reports

In silico analysis identifies novel restriction enzyme combinations that expand reduced ...

Epigenetics is the study of gene expression changes that are not caused by changes in the deoxyribonucleic acid (DNA) sequence. DNA methylation is an epigenetic mark occurring in C-phosphate-G sites (CpGs) that leads to local or regional gene expression ... [Published 7thSpace - Aug 15 2014]
First reported Aug 15 2014 - Updated Aug 15 2014 - 1 reports

UAB Studies Epigenetic Effects of Sunlight Exposure

Sunlight exposure has been shown to affect epigenetic processes like DNA methylation across several human cell-types, including T-lymphocytes. Since DNA methylation can establish gene expression profiles and affect human health, the role of sunlight exposure ... [Published Noodls - Aug 15 2014]
First reported Aug 15 2014 - Updated Aug 15 2014 - 1 reports

Natrium Fluoride Influences Methylation Modifications and Induces Apoptosis in Mouse Early Embryos

This study epigenetically examined the effect of fluoride on early embryos of Kunming mice administered with 0, 20 (low), 60 (medium), and 120 mg/L (high) sodium fluoride (NaF). The results showed that NaF repressed oocyte maturation, fertilization and ... [Published Environmental Science & Technology - Aug 15 2014]
First reported Aug 14 2014 - Updated Aug 14 2014 - 1 reports

Genomic Distribution of H3K9me2 and DNA Methylation in a Maize Genome

by Patrick T. West, Qing Li, Lexiang Ji, Steven R. Eichten, Jawon Song, Matthew W. Vaughn, Robert J. Schmitz, Nathan M. SpringerDNA methylation and dimethylation of lysine 9 of histone H3 (H3K9me2) are two chromatin modifications that can be associated ... [Published Plosone.org - Aug 14 2014]
First reported Aug 13 2014 - Updated Aug 14 2014 - 2 reports

Genetic Blood Test Could Predict Suicide Risk

A chemical alteration in a single human gene linked to stress reactions could give doctors a simple blood test to reliably predict a person’s risk of attempting suicide.The discovery suggests that changes in a gene involved in the function of the brain's ... [Published Lab Medica - Aug 13 2014]
First reported Aug 03 2014 - Updated Aug 04 2014 - 4 reports

Researchers find potential new predictor of stress-related illnesses

PUBLIC RELEASE DATE: 3-Aug-2014SAN ANTONIO (Aug. 2, 2014) ― Scientists studying depression in teens have discovered that subtle changes in a gene can predict how the brain reacts to stress, which can cause such health issues as depression, post-traumatic ... [Published EurekAlert! - Aug 04 2014]

Quotes

"What makes these results so intriguing is that these epigenetic changes could be passed on from mother to child, resulting in these children potentially having future issues and sensitivities around opioid and other addictive substances" said Elisha Wachman, MD, a staff neonatologist at BMC and assistant professorprofessor of pediatrics at BUSM
"It appears that these DNA methylation changes may play a role in the onset of Alzheimer's disease" says Dr. De Jager
Further, "because these findings are also found in the subset of subjects that are not cognitively impaired at the time of death, it appears that these DNA methylation changes may play a role in the onset of Alzheimer's disease" said De Jager...
Fox said, "I don't think you can do that without enabling legislation. I'm not aware of any Town in North Carolina that has done that." She said it may be done in other states, but not in North Carolina

More Content

All (200) | News (159) | Reports (0) | Blogs (39) | Audio/Video (0) | Fact Sheets (0) | Press Releases (2)
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Integrating Multi-Omics for Uncovering the Arch... [Published Plosone.org - 9 hours ago]
In-utero methadone or subutex exposure could al... [Published Medical Xpress - 15 hours ago]
Dysregulated transcriptional and post-translati... [Published 7thSpace - 21 hours ago]
A Method to Evaluate Genome-Wide Methylation in... [Published Plosone.org - Aug 19 2014]
DNA methylation involved in Alzheimer’s disease [Published BioPortfolio - Aug 18 2014]
Targeted gene suppression by inducing de no DNA... [Published 7thSpace - Aug 18 2014]
DNA methylation in brain 'linked to Alzheimer's... [Published Medical News Today - Aug 18 2014]
DNA methylation involved in Alzheimer's disease... [Published DailyMe.Com - Aug 18 2014]
How early changes in DNA methylation affects Al... [Published Sify - Aug 18 2014]
The Emerging Role of Epigenetics in Cardiovascu... [Published Theheart.org - Aug 18 2014]
Epigenomic alterations in Alzheimer disease(Nat... [Published Natureasia.com - Aug 18 2014]
DNA Methylation Modifications Associated with C... [Published Pro Health Network - Aug 17 2014]
DNA methylation involved in Alzheimer's disease [Published Bio-Medicine - Aug 17 2014]
DNA methylation involved in Alzheimer's disease [Published Medical Xpress - Aug 17 2014]
Carolina Beach Council Considers Single Use Pla... [Published Island Gazette Online - Aug 16 2014]
In silico analysis identifies novel restriction... [Published 7thSpace - Aug 15 2014]
UAB Studies Epigenetic Effects of Sunlight Expo... [Published Noodls - Aug 15 2014]
Natrium Fluoride Influences Methylation Modifi... [Published Environmental Science & Technology - Aug 15 2014]
Genomic Distribution of H3K9me2 and DNA Methyla... [Published Plosone.org - Aug 14 2014]
Considerations when investigating lncRNA functi... [Published Elifesciences - Aug 14 2014]
Pleiotropic Effects of a Methyl Donor Diet in a... [Published Plosone.org - Aug 14 2014]
Researchers from Salk Institute for Biological ... [Published 4 Traders - Aug 14 2014]
Genetic Blood Test Could Predict Suicide Risk [Published Lab Medica - Aug 13 2014]
Could a blood test screen for suicide risk? [Published Nursing Times - Aug 13 2014]
Placental FKBP5 Genetic and Epigenetic Variatio... [Published Plosone.org - Aug 12 2014]
Two-Part Series to Explore Use of Biomarkers in... [Published OncLive - Aug 12 2014]
Cologuard Receives FDA Nod for CRC Diagnosis [Published American Journal of Managed Care - Aug 12 2014]
High-throughput DNA analysis shows the importan... [Published 7thSpace - Aug 12 2014]
Africans Asked To Be Aware Of Their Health [Published Spy Ghana - Aug 12 2014]
FDA Approves Cologuard for Colorectal Cancer Sc... [Published American Journal of Public Health - Aug 12 2014]
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Blogs

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Scientists discover how ‘jumping genes’ help bl... [Published UCLA Newsroom - Aug 05 2014]
Black truffles have a syrupy sweet flavor and are highly prized in haute cuisine. A study by an international team of scientists sheds new light on their unique pattern of DNA methylation, a biochemical process. ...
The dynamics of DNA methylation fidelity during... [Published Genome Research current issue - Aug 01 2014]
The faithful transmission of DNA methylation patterns through cell divisions is essential for the daughter cells to retain a proper cell identity. To achieve a comprehensive assessment of methylation fidelity, we implemented a genome-scale hairpin bisulfite ...
Nucleosome repositioning links DNA (de)methylat... [Published Genome Research current issue - Aug 01 2014]
During differentiation of embryonic stem cells, chromatin reorganizes to establish cell type-specific expression programs. Here, we have dissected the linkages between DNA methylation (5mC), hydroxymethylation (5hmC), nucleosome repositioning, and binding ...
Interplay of TRIM28 and DNA methylation in cont... [Published Genome Research current issue - Aug 01 2014]
Reverse transcription-derived sequences account for at least half of the human genome. Although these retroelements are formidable motors of evolution, they can occasionally cause disease, and accordingly are inactivated during early embryogenesis through ...
Modulation of Age- and Cancer-Associated DNA Me... [Published Full Text Reports... - Jul 09 2014]
Modulation of Age- and Cancer-Associated DNA Methylation Change in the Healthy Colon by Aspirin and Lifestyle Source: Journal of the National Cancer Institute Background Aberrant DNA methylation in gene promoters is associated with aging and cancer, but ...
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Press Releases

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Karyopharm Announces Initiation of a Phase 1 St... [Published GlobeNewswire: Acquisitions News - Apr 15 2014]
DBV Technologies and CEA conclude a scientific ... [Published GlobeNewswire: Advertising News - Apr 09 2014]
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