DNA Methylation

Type: Keyphrase
Name: DNA Methylation
First reported 11 hours ago - Updated 6 hours ago - 1 reports

Could a blood test screen for suicide risk?

11:00am Thursday 31st July 2014 content supplied byRead more about getting help if you're feeling suicidal .Where did the story come from?The study was carried out by researchers from Johns Hopkins University School of Medicine and Johns Hopkins Bloomberg ... [Published This is Oxfordshire - 11 hours ago]
First reported 8 hours ago - Updated 8 hours ago - 1 reports

Genome-Wide Analysis in Human Colorectal Cancer Cells Reveals Ischemia-Mediated Expression of Motility Genes via DNA Hypomethylation

by Karolina Skowronki, Joseph Andrews, David I. Rodenhiser, Brenda L. CoomberDNA hypomethylation is an important epigenetic modification found to occur in many different cancer types, leading to the upregulation of previously silenced genes and loss of ... [Published Plosone.org - 8 hours ago]
First reported Jul 31 2014 - Updated 10 hours ago - 1 reports

How black truffles deal with the jumpers in their genome

PUBLIC RELEASE DATE: 30-Jul-2014The black truffle uses reversible epigenetic processes to regulate its genes, and adapt to changes in its surroundings. The 'methylome' - a picture of the genome regulation taking place in the truffle, is published in the ... [Published EurekAlert! - Jul 31 2014]
First reported 21 hours ago - Updated 21 hours ago - 1 reports

Findings from Spanish National Cancer Research Center Provide New Insights into DNA Research (DNA methylation profiling of well-differentiated...

Findings from Spanish National Cancer Research Center Provide New Insights into DNA Research (DNA methylation profiling of well-differentiated thyroid cancer uncovers markers of recurrence free survival)By a News Reporter-Staff News Editor at Cancer Weekly ... [Published 4 Traders - 21 hours ago]
First reported Jul 30 2014 - Updated Jul 30 2014 - 1 reports

Whole-genome bisulfite sequencing of multiple individuals reveals complementary roles of promoter ...

DNA methylation is an important type of epigenetic modification involved in gene regulation. Although strong DNA methylation at promoters is widely recognized to be associated with transcriptional repression, many aspects of DNA methylation remain not ... [Published 7thSpace - Jul 30 2014]
First reported Jul 29 2014 - Updated Jul 29 2014 - 1 reports

Women who smoke while pregnant could alter their children's genes

The largest study of its kind has shown that smoking during pregnancy could cause epigenetic changes in the fetus, resulting in birth defects and health problems later in life. Christina Markunas of the National Institute of Environmental Health Sciences ... [Published Medical Xpress - Jul 29 2014]
First reported Jul 29 2014 - Updated Jul 29 2014 - 1 reports

[News] Epigenetic test for breast cancer

A new study has identified a blood-based epigenetic signature associated with breast cancer risk and mortality. The findings show the potential for an epigenetic test that could eventually be used to predict the development of breast cancer. The researchers ... [Published Lancet Oncology - Jul 29 2014]
First reported Jul 29 2014 - Updated Jul 29 2014 - 1 reports

Current and upcoming approaches to exploit the reversibility of epigenetic mutations in breast ...

DNA methylation and histone modifications are important epigenetic modifications associated with gene (dys)regulation. The epigenetic modifications are balanced by epigenetic enzymes, so-called writers and erasers, such as DNA (de)methylases and histone ... [Published 7thSpace - Jul 29 2014]
First reported Jul 28 2014 - Updated Jul 28 2014 - 1 reports

Measuring whole genome methylation via oxygen channelling chemistry

Successful use of demethylating drugs in cancers underscores the need to analyse whole genome DNA methylation in the clinic. Unfortunately, current methods are difficult to perform and require large amounts of DNA input. Herein we describe the first application ... [Published RSC - Jul 28 2014]
First reported Jul 27 2014 - Updated Jul 27 2014 - 2 reports

Epigenetic changes can drive cancer study shows

A mouse model has been created providing the first in vivo evidence that epigenetic alterations alone can cause cancer. Epigenetic alterations don't change the DNA sequence but how it is 'read.' In particular, DNA methylation, the addition of a methy ... [Published BioPortfolio - Jul 27 2014]
First reported Jul 27 2014 - Updated Jul 27 2014 - 1 reports

New plans for hemophilia patients

Clearing cells to preventcervical cancerA study describes a novel approach to preventing cervical cancer based on findings showing successful reduction in the risk of cervical cancer after removal of a discrete population of cells in the cervix.The findings ... [Published Iran Daily - Jul 27 2014]
First reported Jul 25 2014 - Updated Jul 26 2014 - 2 reports

Study Shows Epigenetic Changes Can Drive Cancer

Houston -- Cancer has long been thought to be primarily a genetic disease, but in recent decades scientists have come to believe that epigenetic changes – which don't change the DNA sequence but how it is 'read' – also play a role in cancer. In particular ... [Published ScienceNewsline - Jul 26 2014]

Quotes

"People with certain gene mutation 'may be more likely to end their life'" reports the Mail Online...
...According to news originating from Madrid, Spain , by NewsRx correspondents, research stated, "Thyroid cancer is a heterogeneous disease with several subtypes characterized by cytological, histological and genetic alterations, but the involvement of epigenetics is not well understood. Here, we investigated the role of aberrant DNA methylation in the development of well-differentiated thyroid tumors."
Dr Gavin Kelsey , said: "Our work provides a proof-of-principle that large-scale, single-cell epigenetic analysis is achievable to help us understand how epigenetic changes control embryonic development. The application of single-cell approaches to epigenetic understanding goes far beyond basic biological research. Future clinical applications could include the analysis of individual cancer cells to provide clinicians with the information to tailor treatments, and improvements in fertility treatment by understanding the potential for epigenetic errors in assisted reproduction technologies."
Dr Simone Ottonello, from the University of Parma, Italy says: "If extended to black truffles from different geographic areas, epigenomic analyses, such as the one described in this work, may shed light on the relationships between DNA methylation and transposon-mediated genome shaping, intraspecific variability and commercially relevant organoleptic traits such as aroma and color"

More Content

All (184) | News (146) | Reports (0) | Blogs (36) | Audio/Video (0) | Fact Sheets (0) | Press Releases (2)
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Genome-Wide Analysis in Human Colorectal Cancer... [Published Plosone.org - 8 hours ago]
5meCpG Epigenetic Marks Neighboring a Primate-C... [Published Plosone.org - 9 hours ago]
DNA changes linked to health effects of childho... [Published 92.9 WLMI - 9 hours ago]
Could a blood test screen for suicide risk? [Published This is Oxfordshire - 11 hours ago]
Findings from Spanish National Cancer Research ... [Published 4 Traders - 21 hours ago]
Researchers at Southwest University for Nationa... [Published Industrial Info Financials - Jul 31 2014]
New technique maps life's effects on our DNA [Published HispanicBusiness.com - Jul 31 2014]
How black truffles deal with the jumpers in the... [Published EurekAlert! - Jul 31 2014]
Blood Test for a Suicide-Risk Gene Proposed [Published Genetic Engineering News - Jul 30 2014]
How a Simple Blood Test Could Predict Suicide Risk [Published MSNBC Newsweek - Jul 30 2014]
DNA hypermethylation of the forkhead box protei... [Published British Journal of Dermatology - Jul 30 2014]
Common dysregulation network in the human prefr... [Published Molecular Systems Biology - Jul 30 2014]
How Smoking Can Affect Your Baby's DNA [Published Image Magazine - Jul 30 2014]
Mitosis Offers Opportunity to Alter Cell Fate [Published PLoS Biology - Jul 30 2014]
23andMe Gets $1.4m from NIH, Publishes Parkinso... [Published Bio-IT World - Jul 30 2014]
Whole-genome bisulfite sequencing of multiple i... [Published 7thSpace - Jul 30 2014]
Women who smoke while pregnant could alter thei... [Published Medical Xpress - Jul 29 2014]
Current and upcoming approaches to exploit the ... [Published 7thSpace - Jul 29 2014]
Dynamic changes of 5hmC in T-cell differentiati... [Published PNAS - Jul 29 2014]
[News] Epigenetic test for breast cancer [Published Lancet Oncology - Jul 29 2014]
Largest Meta-GWAS Yet Uncovers New Genetic Link... [Published Alzheimer Research Forum - Jul 28 2014]
Measuring whole genome methylation via oxygen c... [Published RSC - Jul 28 2014]
Mechanism by Which Child Abuse Influences Adult... [Published Psych Central - Jul 28 2014]
Epigenetic changes can drive cancer study shows [Published BioPortfolio - Jul 27 2014]
New plans for hemophilia patients [Published Iran Daily - Jul 27 2014]
Epigenetic Engineering: Silencing A Gene Can Ca... [Published International Business Times UK - Jul 27 2014]
Child Abuse Affects Gene Responsible For Stress... [Published International Business Times UK - Jul 27 2014]
Study Shows Epigenetic Changes Can Drive Cancer [Published ScienceNewsline - Jul 26 2014]
Epigenetic Changes Can Cause Cancer [Published The Scientist - Jul 25 2014]
Study shows epigenetic changes can drive cancer [Published EurekAlert! - Jul 25 2014]
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Blogs

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Modulation of Age- and Cancer-Associated DNA Me... [Published Full Text Reports... - Jul 09 2014]
Modulation of Age- and Cancer-Associated DNA Methylation Change in the Healthy Colon by Aspirin and Lifestyle Source: Journal of the National Cancer Institute Background Aberrant DNA methylation in gene promoters is associated with aging and cancer, but ...
A Selection of Recent Progress in Cell Biotechn... [Published Fight Aging! - Jul 02 2014]
To a large degree the future of medicine is the future of control over cells. Plus some other stuff around the edges relating to clearing up after cells, removing some of the metabolic waste and misfolded proteins that they can't deal with. These ...
Extreme HOT regions are CpG-dense promoters in ... [Published Genome Research current issue - Jul 01 2014]
Most vertebrate promoters lie in unmethylated CpG-dense islands, whereas methylation of the more sparsely distributed CpGs in the remainder of the genome is thought to contribute to transcriptional repression. Nonmethylated CG dinucleotides are recognized ...
The effect of genotype and in utero environment... [Published Genome Research current issue - Jul 01 2014]
Integrating the genotype with epigenetic marks holds the promise of better understanding the biology that underlies the complex interactions of inherited and environmental components that define the developmental origins of a range of disorders. The ...
What’s going on with Robert O. Young? [Respectf... [Published ScienceBlogs : Combined Feed - Jul 01 2014]
There is no doubt in my mind that Robert O. Young is among the worst cancer quacks I have ever encountered. I’ve never been able to figure out how he manages to continue to practice after over 20 years, given the egregiousness of his quackery. Indeed, ...
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Press Releases

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Karyopharm Announces Initiation of a Phase 1 St... [Published GlobeNewswire: Acquisitions News - Apr 15 2014]
DBV Technologies and CEA conclude a scientific ... [Published GlobeNewswire: Advertising News - Apr 09 2014]
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