fibroblast

Type: Keyphrase
Name: fibroblast
First reported 3 hours ago - Updated 3 hours ago - 1 reports

A Critical Role for the mTORC2 Pathway in Lung Fibrosis

by Wenteh Chang, Ke Wei, Lawrence Ho, Gerald J. Berry, Susan S. Jacobs, Cheryl H. Chang, Glenn D. RosenA characteristic of dysregulated wound healing in IPF is fibroblastic-mediated damage to lung epithelial cells within fibroblastic foci. In these foci, ... [Published Plosone.org - 3 hours ago]
First reported 15 hours ago - Updated 15 hours ago - 1 reports

Silab Debuts Anti-Aging Solution

Elasticity loss and tissue stiffening are signs of aging resulting from glycation. To fight against these occurrences, Silab offers Deglysome, a double effect active ingredient capable of limiting cellular and tissue damages caused by glycation and Advanced ... [Published Happi - 15 hours ago]
First reported 21 hours ago - Updated 21 hours ago - 1 reports

Regenerative Medicine Makes Old Immune Organ Young Again

By , Ph.D.The desire to culture replacement organs for damaged or diseased ones has been a significant driving force since regenerative medicine’s infancy. Now, for the first time, University of Edinburgh researchers have regrown a thymus in a living ... [Published Medical Design Online - 21 hours ago]
First reported 21 hours ago - Updated 21 hours ago - 1 reports

Enzymatic Oxidation of Cholesterol: Properties and Functional Effects of Cholestenone in Cell Membranes

by Maarit Neuvonen, Moutusi Manna, Sini Mokkila, Matti Javanainen, Tomasz Rog, Zheng Liu, Robert Bittman, Ilpo Vattulainen, Elina IkonenBacterial cholesterol oxidase is commonly used as an experimental tool to reduce cellular cholesterol content. That ... [Published Plosone.org - 21 hours ago]
First reported Aug 26 2014 - Updated Aug 26 2014 - 1 reports

Scientists Grow Functional Organ From Scratch, As Transplantation Gives Way To Engineering

The esteemed astronomer Carl Sagan once said, “If you wish to make an apple pie from scratch, you must first invent the universe.” He wasn’t hyperbolizing, necessarily — “from scratch” implies a sort of initial creation. But what would the late scientist ... [Published Medical Daily - Aug 26 2014]
First reported Aug 26 2014 - Updated Aug 26 2014 - 1 reports

Pharmaceutical or cosmetic composition containing nicotinic acid adenine dinucleotide phosphate or derivative thereof

Provided are a method of preparing a zinc oxide nanostructure electrode and a method of preparing a dye-sensitized solar cell using the same. The present invention relates to a use of nicotinic acid adenine dinucleotide phosphate or a derivative thereof ... [Published Free Patents Online - Aug 26 2014]
First reported Aug 26 2014 - Updated Aug 26 2014 - 1 reports

Research and Markets: OpportunityAnalyzer: Diabetic Foot Ulcers - Opportunity Analysis and Forecasts to 2017 - Event-Driven Update

Research and MarketsFor the past 15 years, Regranex (becaplermin) has been the only pharmacologic wound-healing agent available; however, it is rarely used due a perceived lack of efficacy.The DFU market is now set to enter an exciting phase with the ... [Published Stock Nod - Aug 26 2014]
First reported Aug 25 2014 - Updated Aug 25 2014 - 5 reports

Transplant of Lab-Tweaked Cells Generates Working Organ

Various types of cells have been developed in the laboratory, raising hopes that transplantable organs could be developed outside the body. Still, a much-desired goal—the generation of fully functional laboratory-grown organs—has yet to be achieved. Not ... [Published Genetic Engineering News - Aug 25 2014]
First reported Aug 25 2014 - Updated Aug 25 2014 - 1 reports

Polysaccharide-Based Networks from Homogeneous Chitosan-Tripolyphosphate Hydrogels: Synthesis and Characterization

Polysaccharide networks, in the form of hydrogels and dried membranes based on chitosan and on the cross-linker tripolyphosphate (TPP), were developed using a novel approach. TPP was incorporated into chitosan by slow diffusion to favor a controlled gelation. ... [Published Biomacromolecules - Aug 25 2014]
First reported Aug 25 2014 - Updated Aug 25 2014 - 1 reports

Stem Cells and Growth Factors: What You Should Know

Editor's note: This is the edited version of an article that originally ran in the April 2014 issue of Skin Inc. magazine. All rights reserved.The use of stem cells in skin care and esthetic medicine has generated a lot of excitement. However, there remains ... [Published Global Cosmetic Industry Magazine - Aug 25 2014]
First reported Aug 25 2014 - Updated Aug 25 2014 - 1 reports

Surface-Initiated Hyperbranched Polyglycerol as an Ultralow-Fouling Coating on Glass, Silicon, and Porous Silicon Substrates

Anionic ring-opening polymerization of glycidol was initiated from activated glass, silicon, and porous silicon substrates to yield thin, ultralow-fouling hyperbranched polyglycerol (HPG) graft polymer coatings. Substrates were activated by deprotonation ... [Published ACS Applied Materials & Interfaces - Aug 25 2014]
First reported Aug 21 2014 - Updated Aug 21 2014 - 1 reports

Rosiglitazone Inhibits TGF-β 1 Induced Activation of Human Tenon Fibroblasts via p38 Signal Pathway

by Yong-Heng Luo, Ping-Bo Ouyang, Jiao Tian, Xiao-Jian Guo, Xuan-Chu DuanPurposeTransdifferentiation of human Tenon fibroblasts to myofibroblasts and subsequent deposition of extracellular matrix is a key step in the scarring after glaucoma filtration ... [Published Plosone.org - Aug 21 2014]

Quotes

...In both cases, the results were identical, as Professor Erben explains: "The absorption of in the kidneys increased significantly. This led to an increase in blood pressure and to a rapid expansion in the size of the heart muscle."
"The ability to grow replacement organs from cells in the lab is one of the 'holy grails' in regenerative medicine. But the size and complexity of lab-grown organs has so far been limited,” said Clare Blackburn, professor from the Medical Research Council’s Centre for Regenerative Medicine at the University of Edinburgh and lead researcher of the study, in a recent press release . “By directly reprogramming cells we've managed to produce an artificial cell type that, when transplanted, can form a fully organised and functional organ. This is an important first step towards the goal of generating a clinically useful artificial thymus in the lab."
"It remains to be seen whether, in the long term, cells generated using direct reprogramming will be able to maintain their specialized form and avoid problems such as tumor formation" Dr. Paolo de Coppi, a researcher of regenerative therapies, told the BBC
...happens after injury, perhaps we can use some sort of chemical or drug to restore regeneration and make muscle instead of scar," Hatzopoulos said. "We think there is an opportunity here to improve the way we treat people who come into the clinic after myocardial infarction."

More Content

All (422) | News (376) | Reports (0) | Blogs (42) | Audio/Video (0) | Fact Sheets (1) | Press Releases (3)
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Proinflammation of Aging Central Arteries: A Mi... [Published Sexual Development - 1 hour ago]
Folate Ligand Anchored Liquid Crystal Microdrop... [Published Langmuir - 1 hour ago]
A Critical Role for the mTORC2 Pathway in Lung ... [Published Plosone.org - 3 hours ago]
Fetal Myelomeningocele Closure: Technical Consi... [Published Sexual Development - 7 hours ago]
Origin of myofibroblasts and cellular events tr... [Published Kidney International - 8 hours ago]
Paradoxical mineral nutrients [Published Hospital Pharmacy Europe - 10 hours ago]
Cell Assays – Present & Future (Part Two) [Published Select Science - 12 hours ago]
Silab Debuts Anti-Aging Solution [Published Happi - 15 hours ago]
Metastatic tumor evolution and organoid modelin... [Published 7thSpace - 19 hours ago]
Regenerative Medicine Makes Old Immune Organ Yo... [Published Medical Design Online - 21 hours ago]
Enzymatic Oxidation of Cholesterol: Properties ... [Published Plosone.org - 21 hours ago]
Biocontrol of Aspergillus Species on Peanut Ker... [Published Plosone.org - Aug 26 2014]
Scientists Grow Functional Organ From Scratch, ... [Published Medical Daily - Aug 26 2014]
Researchers Find That Coronary Arteries can Pro... [Published MedIndia - Aug 26 2014]
How Scientists Grew a New Organ Inside a Mouse'... [Published Motherboard Magazine - Aug 26 2014]
Thymus gland grown from reprogrammed cells in lab [Published Fierce Biotech Research - Aug 26 2014]
Scientists have grown a fully functional organ ... [Published Examiner.com - Aug 26 2014]
Research and Markets: OpportunityAnalyzer: Diab... [Published Stock Nod - Aug 26 2014]
OpportunityAnalyzer: Diabetic Foot Ulcers - Opp... [Published Individual.com - Aug 26 2014]
Scientists grow fully functional organ from tra... [Published Noodls - Aug 26 2014]
Sorrento Awarded NIH Grant to Advance Immunothe... [Published ADVFN India - Aug 26 2014]
RepliCel Announces 2014 Second Quarter Financia... [Published Fat Pitch Financials - Aug 26 2014]
Immune organ made from lab cells [Published OnMedicanet - Aug 26 2014]
Pharmaceutical or cosmetic composition containi... [Published Free Patents Online - Aug 26 2014]
Head nodule causes significant trauma [Published Australian Doctor - Aug 26 2014]
Nuclear Glycolytic Enzyme Enolase of Toxoplasma... [Published Plosone.org - Aug 25 2014]
Polysaccharide-Based Networks from Homogeneous ... [Published Biomacromolecules - Aug 25 2014]
Stem Cells and Growth Factors: What You Should ... [Published Global Cosmetic Industry Magazine - Aug 25 2014]
Transplant of Lab-Tweaked Cells Generates Worki... [Published Genetic Engineering News - Aug 25 2014]
Surface-Initiated Hyperbranched Polyglycerol a... [Published ACS Applied Materials & Interfaces - Aug 25 2014]
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Blogs

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Growing a New Thymus From Engineered Cells [Published Fight Aging! - Aug 25 2014]
The thymus is vital to generation of new immune cells , and the fact that it atrophies early in life, turning a river of new cells into a trickle, is one of the factors placing an effective cap on the adult immune cell population. In part because ...
Ebola 2014: An evolving epidemic [Published H5N1 - Aug 18 2014]
Thanks to Greg Folkers for sending the link to this report in Annals of Internal Medicine: Ebola Hemorrhagic Fever in 2014: The Tale of an Evolving EpidemicEbola. Excerpt:The current outbreak, which began in December 2013 and is the largest ever, was ...
Proteins critical to wound healing identified [Published WUSTL Medicine & Healthcare News - Aug 18 2014]
Rei Nakamura, PhD Pictured are normal blood vessels of a mouse’s retina. Mice missing two important proteins of the vascular system develop normally and appear healthy in adulthood, as long as they don’t become injured. If they do, their wounds don’t ...
Extract from GM Red Sage Accelerates Burn Wound... [Published CropBiotech Update - Aug 13 2014]
The human acidic fibroblast growth factor 1 (FGF-1) plays a role in angiogenesis and tissue repair. Red sage (Salvia miltiorrhiza) is an herb medicine used in traditional Chinese treatment of various diseases. Dehu Liu, from the Chinese Academy of Agricultural ...
Are Th22 cells the reason why beta interferon m... [Published Multiple Sclerosis Research - Aug 11 2014]
Rolla S, Bardina V, De Mercanti S, Quaglino P, Palma RD, Gned D, Brusa D, Durelli L, Novelli F, Clerico M.  Th22 cells are expanded in multiple sclerosis and are resistant to IFN-β  J Leukoc Biol. 2014 Aug. pii: jlb.5A0813-463RR. [Epub ahead of print]Th1 ...
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Press Releases

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Blueprint Medicines Presents Positive Data on F... [Published GlobeNewswire: Acquisitions News - Apr 07 2014]
Blueprint Medicines to Present on the First Iso... [Published GlobeNewswire: Acquisitions News - Mar 24 2014]
Alpha and Omega Gene Therapy Eye Cream's Scient... [Published PR Newswire - Dec 19 2013]
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