Publication: Fight Aging!

First reported Apr 18 2014 - Updated 19 hours ago - 1 reports

Turning Cells into Programmable Medical Devices

Targeted delivery of drugs and proteins to modify metabolism and cell behavior may in the future be accomplished by engineered cells. Cells already do a great many useful things, so why reinvent the wheel when there is existing machinery that can be ... [Published Fight Aging! - Apr 18 2014]
First reported Apr 18 2014 - Updated Apr 19 2014 - 1 reports

Somatic Cell Nuclear Transfer Achieved in Adult Human Cells

The future of cell therapies includes regenerative treatments and tissue engineering , as well as many other possibilities, but it all depends on the development of highly efficient, low-cost ways to generate a ready supply of cells of any given type ... [Published Fight Aging! - Apr 18 2014]
First reported Apr 18 2014 - Updated Apr 18 2014 - 1 reports

Is Parkinson's an Autoimmune Disease?

This is an interesting view on the later stages Parkinson's disease that seems fairly orthogonal to the present mainstream focus on α-synuclein and its removal : The cause of neuronal death in Parkinson's disease is still unknown, but a new study ... [Published Fight Aging! - Apr 18 2014]
First reported Apr 18 2014 - Updated Apr 18 2014 - 1 reports

The Crossroads for Human Longevity

In these years we stand at the crossroads for human longevity. A long, slow, and largely unintentional upward trend in health and life expectancy has been running for near two hundred years now, caused by increases in wealth and technological progress, ... [Published Fight Aging! - Apr 18 2014]
First reported Apr 17 2014 - Updated Apr 17 2014 - 1 reports

A Midlife Crisis for the Mitochondrial Free Radical Theory of Aging

Here is an open access paper that covers some of the challenges that have faced the interpretation of just how and why it is that mitochondria have an important role in the aging process . The mitochondrial free radical theory of aging has been broadly ... [Published Fight Aging! - Apr 17 2014]
First reported Apr 17 2014 - Updated Apr 17 2014 - 1 reports

Public Views on the Future of Technology

A few things are of interest in this survey, with one being that a majority of people don't like specific instances of societal change resulting from technological advances if asked about them, which isn't much of a surprise given human nature. Another ... [Published Fight Aging! - Apr 17 2014]
First reported Apr 16 2014 - Updated Apr 16 2014 - 1 reports

An Update on DNA Methylation Patterns as a Biomarker of Aging

The research community is very interested in a reliable method of measuring biological age: not how old you are in years, but how far along you are in the aging process, how much damage has accumulated in cells and macromolecules and how well or poorly ... [Published Fight Aging! - Apr 16 2014]
First reported Apr 16 2014 - Updated Apr 16 2014 - 1 reports

A Canine Longitudinal Aging Study Proposed

As noted below researchers are making an effort to establish the basis for a comprehensive study of aging in longer-lived species. Most present work on aging in mammals takes place in mice and rats, and while there are many similarities between mice ... [Published Fight Aging! - Apr 16 2014]
First reported Apr 16 2014 - Updated Apr 16 2014 - 1 reports

A Decellularized Oesophagus Demonstrated in Rats

Researchers here make use of the process of decellularization to match a donor organ to the recipient. In the ideal procedure, donor cells are removed and the remaining extracellular matrix of the organ is repopulated with the recipient's cells, ... [Published Fight Aging! - Apr 16 2014]
First reported Apr 15 2014 - Updated Apr 15 2014 - 1 reports

What is Robust Mouse Rejuvenation, and Why Should We Care?

SENS, the Strategies for Engineered Negligible Senescence is a detailed research plan for developing the means to prevent and reverse degenerative aging by repairing its causes. SENS assembles the list of causes from the present scientific consensus ... [Published Fight Aging! - Apr 15 2014]
First reported Apr 15 2014 - Updated Apr 15 2014 - 1 reports

More Evidence of the Inverse Relationship Between Dementia and Cancer Mortality

It is perhaps unexpected that incidence of dementia and incidence of cancer seem to have a robust inverse relationship , one that has shown up in multiple different study populations. In general we think of aging as a global phenomenon in the body ... [Published Fight Aging! - Apr 15 2014]
Entities: Cancer, Dementia, Mortality
First reported Apr 15 2014 - Updated Apr 15 2014 - 1 reports

The Fragile Elderly Hip

Here is an open access review that looks at what is known of the proximate mechanisms that cause increasing fragility of bone with advancing age. These are not the root causes, but it remains to be determined how exactly the laundry list of primary ... [Published Fight Aging! - Apr 15 2014]

Quotes

...Robert Lanza , chief scientific officer at Advanced Cell Technology , says that was an important step, but not ideal for medical purposes. "There are many diseases, whether it's diabetes, Alzheimer's or Parkinson's disease , that usually increase with age" Lanza says...
...thought that neurons are protected from attacks from the immune system, in part, because they do not display antigens on their cell surfaces. "That idea made sense because, except in rare circumstances, our brains cannot make new neurons to replenish ones killed by the immune system. But, unexpectedly, we found that some types of neurons can display antigens."
...The platform is also highly modular, enabling the biosensors to be customized to recognize factors of relevance to various patients' needs. "By linking the output of these biosensors to genetic programs, one can build in a certain logical command, such as 'turn the output gene on when you sense this factor but not that factor In that way, you could program a cell-based therapy to specify which cells it should kill."
"Dogs offer tremendous potential as a model system for human aging. They share many genetic characteristics with humans that let us combine traditional demographic and epidemiological approaches with new techniques like comparative genomics . Unlike any other model system for aging, dogs share our environment and, increasingly, our health care options. Once developed, a canine model holds enormous promise, and we expect it to have a significant impact on aging research."

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sort by: Date | Relevance
Somatic Cell Nuclear Transfer Achieved in Adult... [Published Fight Aging! - Apr 18 2014]
Is Parkinson's an Autoimmune Disease? [Published Fight Aging! - Apr 18 2014]
Turning Cells into Programmable Medical Devices [Published Fight Aging! - Apr 18 2014]
The Crossroads for Human Longevity [Published Fight Aging! - Apr 18 2014]
A Midlife Crisis for the Mitochondrial Free Rad... [Published Fight Aging! - Apr 17 2014]
Public Views on the Future of Technology [Published Fight Aging! - Apr 17 2014]
An Update on DNA Methylation Patterns as a Biom... [Published Fight Aging! - Apr 16 2014]
A Canine Longitudinal Aging Study Proposed [Published Fight Aging! - Apr 16 2014]
A Decellularized Oesophagus Demonstrated in Rats [Published Fight Aging! - Apr 16 2014]
What is Robust Mouse Rejuvenation, and Why Shou... [Published Fight Aging! - Apr 15 2014]
More Evidence of the Inverse Relationship Betwe... [Published Fight Aging! - Apr 15 2014]
The Fragile Elderly Hip [Published Fight Aging! - Apr 15 2014]
Commercial Blood Factories Lie Ahead [Published Fight Aging! - Apr 14 2014]
Learning to Reverse Aspects of Cell Aging By Ob... [Published Fight Aging! - Apr 14 2014]
TRF2 as a Potential Biomarker of Cellular Senes... [Published Fight Aging! - Apr 14 2014]
SENS Research Foundation Newsletter, April 2014 [Published Fight Aging! - Apr 11 2014]
Nose Reconstruction With Tissue Engineered Cart... [Published Fight Aging! - Apr 11 2014]
Creation of Functional Tissue Engineered Vaginas [Published Fight Aging! - Apr 11 2014]
No One Cares About Research Funding [Published Fight Aging! - Apr 10 2014]
Sensory Neuron Function and Calorie Restriction... [Published Fight Aging! - Apr 10 2014]
Stem Cells Show Promise in Stroke Treatment [Published Fight Aging! - Apr 10 2014]
Reversal of Hepatocyte Senescence [Published Fight Aging! - Apr 09 2014]
Cryonics in Canada [Published Fight Aging! - Apr 09 2014]
Theorizing on Mitochondria and Iron Homeostasis... [Published Fight Aging! - Apr 09 2014]
D-Glucosamine as an Example of Calorie Restrict... [Published Fight Aging! - Apr 08 2014]
Thymus Regeneration Demonstrated via Increased ... [Published Fight Aging! - Apr 08 2014]
On Body Temperature and Pace of Aging [Published Fight Aging! - Apr 08 2014]
More Attention for "Death is Wrong" [Published Fight Aging! - Apr 08 2014]
Targeting Cancer With Magnetic Nanoparticles [Published Fight Aging! - Apr 07 2014]
Arguing for More Research into Parabiosis Effects [Published Fight Aging! - Apr 07 2014]
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sort by: Date | Relevance
Somatic Cell Nuclear Transfer Achieved in Adult... [Published Fight Aging! - Apr 18 2014]
The future of cell therapies includes regenerative treatments and tissue engineering , as well as many other possibilities, but it all depends on the development of highly efficient, low-cost ways to generate a ready supply of cells of any given type ...
Is Parkinson's an Autoimmune Disease? [Published Fight Aging! - Apr 18 2014]
This is an interesting view on the later stages Parkinson's disease that seems fairly orthogonal to the present mainstream focus on α-synuclein and its removal : The cause of neuronal death in Parkinson's disease is still unknown, but a new study ...
Turning Cells into Programmable Medical Devices [Published Fight Aging! - Apr 18 2014]
Targeted delivery of drugs and proteins to modify metabolism and cell behavior may in the future be accomplished by engineered cells. Cells already do a great many useful things, so why reinvent the wheel when there is existing machinery that can be ...
The Crossroads for Human Longevity [Published Fight Aging! - Apr 18 2014]
In these years we stand at the crossroads for human longevity. A long, slow, and largely unintentional upward trend in health and life expectancy has been running for near two hundred years now, caused by increases in wealth and technological progress, ...
A Midlife Crisis for the Mitochondrial Free Rad... [Published Fight Aging! - Apr 17 2014]
Here is an open access paper that covers some of the challenges that have faced the interpretation of just how and why it is that mitochondria have an important role in the aging process . The mitochondrial free radical theory of aging has been broadly ...
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