G-CSF

Type: Keyphrase
Name: G-CSF
Publicerad 22 hours ago - uppdaterad 22 hours ago - 1 rapporter

Leaders in Research & Scientific Sessions

There are a number of perennial destinations for the molecular imaging set that deliver cutting-edge research and promote clinical discussion, but, for many clinicians and researchers, the Society of Nuclear Medicine and Molecular Imaging’s Annual Meeting ... [Published MolecularImaging.net - 22 hours ago]
Publicerad Sep 16 2014 - uppdaterad Sep 16 2014 - 1 rapporter

Penticton family fights to recover cancer drug costs

PENTICTON, BC – Shortly after their son’s first birthday, Aaron and Ana Moen received the devastating news that their boy has cancer.Aeson Moen is now 17-months old and entering his fifth cycle of chemotherapy this week.But the treatment doesn’t end ... [Published Global News Canada - Sep 16 2014]
Publicerad Sep 08 2014 - uppdaterad Sep 08 2014 - 1 rapporter

Ex Vivo Expansion of Hematopoietic Stem and Progenitor Cells

Reuters Health InformationBy Will Boggs MDSeptember 08, 2014NEW YORK (Reuters Health) - Researchers have found a new method to expand hematopoietic stem and progenitor cells ex vivo without genetic modification."We have now developed a novel approach ... [Published Diabetes Care - Sep 08 2014]
Publicerad Sep 02 2014 - uppdaterad Sep 02 2014 - 1 rapporter

Mobilization of healthy donors with plerixafor affects the cellular composition of T-cell receptor ...

HLA-haploidentical hematopoietic stem cell transplantation (HSCT) is suitable for patients lacking related or unrelated HLA-matched donors. Herein, we investigated whether plerixafor (MZ), as an adjunct to G-CSF, facilitated the collection of mega-doses ... [Published 7thSpace - Sep 02 2014]
Publicerad Sep 02 2014 - uppdaterad Sep 02 2014 - 1 rapporter

Granulocyte colony-stimulating factor off-target effect on nerve outgrowth promotes prostate cancer development - Abstract

The hematopoietic growth factor granulocyte colony-stimulating factor (G-CSF) has a role in proliferation, differentiation and migration of the myeloid lineage and in mobilizing hematopoietic stem and progenitor cells into the bloodstream.However, G-CSF ... [Published UroToday - Sep 02 2014]
Publicerad Aug 29 2014 - uppdaterad Aug 29 2014 - 1 rapporter

Mutation disables innate immune system

A Ludwig Maximilian University of Munich team has shown that defects in the JAGN1 gene inhibit the function of a specific type of white blood cells, and account for a rare congenital immune deficiency that increases vulnerability to life-threatening ... [Published Medical Xpress - Aug 29 2014]
Publicerad Aug 28 2014 - uppdaterad Aug 28 2014 - 1 rapporter

Green Cross Neulapeg biosimilar approved in South Korea

South Korea’s Green Cross says that the country’s Ministry of Food and Drug Safety has granted marketing authorization for Neulapeg (pegteograstim), a treatment for abnormally low level of neutrophils in patient undergoing chemotherapy.Neulapeg is a biosimilar ... [Published Pharma Letter - Aug 28 2014]
Publicerad Aug 27 2014 - uppdaterad Aug 27 2014 - 1 rapporter

South Korean FDA Approval For Green Cross’ Neulapeg®

Tech & PharmaAugust 27, 2014Green Cross receives regulatory approval for its once-per-cycle dose neutropenia drug, Neulapeg®.AsianScientist (Aug. 27, 2014) – Green Cross, a South Korean biopharmaceutical company, has been granted South Korea’s Ministry ... [Published Asian Scientist - Aug 27 2014]
Publicerad Aug 26 2014 - uppdaterad Aug 26 2014 - 1 rapporter

G-CSF therapy improved survival in patients with alcoholic hepatitis

Patients with severe alcoholic hepatitis treated with standard therapy plus granulocyte colony-stimulating factor had a greater survival rate after therapy compared with those treated without it, according to data from a recent study.Forty-six patients ... [Published Orthopedics Today - Aug 26 2014]
Publicerad Aug 22 2014 - uppdaterad Aug 22 2014 - 1 rapporter

Anti-Obesity Effects of Granulocyte-Colony Stimulating Factor in Otsuka-Long-Evans-Tokushima Fatty Rats

by Yonggu Lee, Yi-Sun Song, Cheng-Hu Fang, Byung-Im So, Jun-Young Park, Hyun-Woo Joo, In-Hwa Park, Guang-Yin Shen, Jeong-Hun Shin, Hyuck Kim, You-Heon Ahn, Kyung-Soo KimGranulocyte-colony stimulating factor (G-CSF) has molecular structures and intracellular ... [Published Plosone.org - Aug 22 2014]
Entiteter: G-CSF, Anti-Obesity, Rats
Publicerad Aug 21 2014 - uppdaterad Aug 21 2014 - 1 rapporter

Abbott To Develop Portable Blood Tests For Concussions

Summary Abbott joined forces with the United States Department of Defense for developing portable blood tests for concussions. The tests will help Abbott generate significant revenues not only from the military personnel, but also from civilian people ... [Published Seeking Alpha - Aug 21 2014]
Publicerad Aug 15 2014 - uppdaterad Aug 15 2014 - 2 rapporter

Japan Recommends Long-Acting G-CSF Filgrastim

Article # 28140814010Posted: Aug. 15, 2014 2:35 AM GMTExecutive SummaryJapan recommended for approval two pharmaceutical products on August 8, including the new long-acting G-CSF formulation G-Lasta (genetic recombinant pegfilgrastim) from Kyowa Hakko ... [Published Health News Daily - Aug 15 2014]

Citat

"The process of clinical development relates to creating a GMP-compliant process and scaled-up production of cells and proteins," Dr. Refaeli said. "In addition, we will need some toxicology studies on larger animals (dogs or pigs) for the proteins in order to obtain FDA approval to commence first-in-human clinical trials."
The senior investigator of the study Prof. Dr. Martin Witzenrath from Charité - Universitätsmedizin Berlin, concluded: "These first results in animal models are very promising. NOX-D19 seems to effectively neutralize C5a and have an effect on the overwhelming immune response that leads to unnecessary damage. NOX-D19 could thus give protection against lung and extra-pulmonary organ failure in pneumococcal pneumonia-induced sepsis and may offer an important adjuvant treatment strategy for improved survival in pneumococcal sepsis."
Single-dose MZ was given to 30 ` "poor mobilizers? (PM) failing to attain ?40 CD34+ HSCs/?L after 4 daily G-CSF doses and/or with predicted apheresis yields ?12.0x106 CD34+ cells/kg recipient?s body weight."
"Jagunal homolog 1 is a critical regulator of neutrophil function in fungal host defense." Gerald Wirnsberger, et al. Nature Genetics (2014) DOI: 10.1038/ng.3070...

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Leaders in Research & Scientific Sessions [Published MolecularImaging.net - 22 hours ago]
Penticton family fights to recover cancer drug ... [Published Global News Canada - Sep 16 2014]
IL-10 and NOS2 Modulate Antigen-Specific Reacti... [Published Plosone.org - Sep 12 2014]
Paying it forward on ‘orphan disease’ Fanconi A... [Published Philippine Daily Inquirer - Sep 11 2014]
Filgrastim BLA Approval Nears; Hospitals Ready? [Published Pharmacy Practice News - Sep 09 2014]
Ex Vivo Expansion of Hematopoietic Stem and Pro... [Published Diabetes Care - Sep 08 2014]
Two Presentations at International Conferences ... [Published PipelineReview - Sep 04 2014]
Mobilization of healthy donors with plerixafor ... [Published 7thSpace - Sep 02 2014]
Granulocyte colony-stimulating factor off-targe... [Published UroToday - Sep 02 2014]
Mutation disables innate immune system [Published Medical Xpress - Aug 29 2014]
Early Activation of MAP Kinases by Influenza A ... [Published Plosone.org - Aug 28 2014]
Green Cross Neulapeg biosimilar approved in Sou... [Published Pharma Letter - Aug 28 2014]
South Korean FDA Approval For Green Cross’ Neul... [Published Asian Scientist - Aug 27 2014]
G-CSF therapy improved survival in patients wit... [Published Orthopedics Today - Aug 26 2014]
Anti-Obesity Effects of Granulocyte-Colony Stim... [Published Plosone.org - Aug 22 2014]
Abbott To Develop Portable Blood Tests For Conc... [Published Seeking Alpha - Aug 21 2014]
Deprived TLR9 Expression in Apparently Healthy ... [Published Plosone.org - Aug 19 2014]
Stem Cell Transplantation [Published Multiple Sclerosis Research - Aug 17 2014]
Japan Recommends Long-Acting G-CSF Filgrastim [Published Health News Daily - Aug 15 2014]
Japan Recommends Long-Acting G-CSF Filgrastim [Published BioPortfolio - Aug 15 2014]
Combinatorial G-CSF/AMD3100 Treatment in Cardia... [Published Plosone.org - Aug 14 2014]
Sandoz International’s Zarxio on Path to Become... [Published BioPortfolio - Aug 12 2014]
Intracutaneous paste composition [Published PharmCast - Aug 12 2014]
Autologous hematopoietic stem cell transplantat... [Published Multiple Sclerosis Journal RSS feed -- OnlineFi ... - Jul 30 2014]
US FDA accepts Sandoz biologics license applica... [Published PharmaBiz - Jul 25 2014]
Research and Markets: World Market for Biosimil... [Published Business Wire Health News - Jul 23 2014]
The World Market for Biosimlars (EPO, G-CSF, HG... [Published PR Newswire: Entertainment & Media - Jul 21 2014]
Research and Markets: The World Market for Bios... [Published Business Wire Health News - Jun 06 2014]
Neumedicines Publishes Data Demonstrating that ... [Published GlobeNewswire: Sports News - Jun 02 2014]
Compositions and methods of vascular injury repair [Published PharmCast - May 16 2014]
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Stem Cell Transplantation [Published Multiple Sclerosis Research - Aug 17 2014]
Autologous hematopoietic stem cell transplantat... [Published Multiple Sclerosis Journal RSS feed -- OnlineFi ... - Jul 30 2014]
Research and Markets: World Market for Biosimil... [Published Business Wire Health News - Jul 23 2014]
The World Market for Biosimlars (EPO, G-CSF, HG... [Published PR Newswire: Entertainment & Media - Jul 21 2014]
Research and Markets: The World Market for Bios... [Published Business Wire Health News - Jun 06 2014]
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Pressreleaser

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Neumedicines Publishes Data Demonstrating that ... [Published GlobeNewswire: Sports News - Jun 02 2014]
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