gene deletion

Type: Keyphrase
Name: gene deletion
First reported Apr 16 2014 - Updated Apr 16 2014 - 1 reports

PROTALEX : "Protein a Compositions and Methods of Use" in Patent Application Approval Process

By a News Reporter-Staff News Editor at Diabetes Week -- A patent application by the inventor Mann, Paul ( Albuquerque, NM ), filed on December 5, 2013 , was made available online on April 10, 2014 , according to news reporting originating from Washington, ... [Published 4 Traders - Apr 16 2014]
First reported Apr 13 2014 - Updated Apr 13 2014 - 1 reports

Identification of Novel Genomic Aberrations in AML-M5 in a Level of Array CGH

To assess the possible existence of unbalanced chromosomal abnormalities and delineate the characterization of copy number alterations (CNAs) of acute myeloid leukemia-M5 (AML-M5), R-banding karyotype, oligonucelotide array CGH and FISH were performed ... [Published PLoS medicine - Apr 13 2014]
First reported Apr 11 2014 - Updated Apr 11 2014 - 1 reports

Biology Maybe Right, Chemistry Ridiculously Wrong

A reader sent along a puzzled note about this paper that's out in Science . It's from a large multicenter team (at least nine departments across the US, Canada, and Europe), and it's an ambitious effort to profile 3250 small molecules in a broad chemogenomics ... [Published In the Pipeline - Apr 11 2014]
First reported Apr 09 2014 - Updated Apr 09 2014 - 1 reports

Medical News Today: Scientists find link between brain development and breast cancer gene

It is well known that females with a BRCA1 gene mutation are at a much higher risk of developing breast and ovarian cancers. Now, researchers from the Salk Institute in La Jolla, CA, have discovered what they describe as a "crucial" link between brain ... [Published Medical News Today - Apr 09 2014]
Entities: BRCA1, Breast Cancer, Neuron
First reported Apr 02 2014 - Updated Apr 02 2014 - 1 reports

BACE1 ([small beta]-secretase) inhibitors for the treatment of Alzheimer's disease

BACE1 (β-secretase, memapsin 2, Asp2) has emerged as a promising target for the treatment of Alzheimer's disease. BACE1 is an aspartic protease which functions in the first step of the pathway leading to the production and deposition of amyloid-β peptide ... [Published RSC - Apr 02 2014]
First reported Apr 02 2014 - Updated Apr 02 2014 - 1 reports

NAI Alumni Seminar Series: Hopanoid Biosynthesis and Function in Methanotrophic Bacteria

Presenter: Paula Welander (Stanford University)When: April 7th, 2014 11AM PDTThe majority of life's history has been dominated by microbes whose metabolic inventions have significantly altered the Earth's surface environment and, in turn, impacted the ... [Published SpaceRef - Apr 02 2014]
First reported Mar 24 2014 - Updated Mar 25 2014 - 1 reports

FAT10 Gene Linked To Fat And Aging In Mice: Could Deleting A Fat Gene Promote Weight Loss?

Sounds like the perfect test run for a eugenics experiment: Find and delete a single gene as a way to reduce body fat while extending lifespan. Sadly or happily (depending on your point of view), science is not there yet, but many would still call the ... [Published Medical Daily - Mar 24 2014]
First reported Mar 23 2014 - Updated Mar 23 2014 - 1 reports

Selection of Higher Order Regression Models in the Analysis of Multi-Factorial Transcription Data

Many studies examine gene expression data that has been obtained under the influence of multiple factors, such as genetic background, environmental conditions, or exposure to diseases. The interplay of multiple factors may lead to effect modification ... [Published PLoS medicine - Mar 23 2014]
First reported Mar 21 2014 - Updated Mar 21 2014 - 1 reports

Ovalbumin-induced experimental allergic asthma is Toll-like receptor 2 dependent

Authors: Li, Xiaodi; Chen, Qiu; Chu, Chu; You, Haizhang; Jin, Meifang; Zhao, Xianhong; Zhu, Xueming; Zhou, Weifang; Ji, WeiSource: Allergy and Asthma Proceedings, Volume 35, Number 2, March/April 2014 , pp. e15-e20(6)Publisher: OceanSide Publications, ... [Published IngentaConnect Publication AAP - Mar 21 2014]
First reported Mar 15 2014 - Updated Mar 15 2014 - 1 reports

Could APP, Not Aβ, Explain Epileptic Activity in Alzheimer’s?

People with Alzheimer’s run a high risk for seizures, as do mice that model the disease. While Aβ has seemed the most likely cause for this neuronal hyperactivity, a study in the March 12 Journal of Neuroscience suggests that the Aβ precursor protein ... [Published Alzheimer Research Forum - Mar 15 2014]
First reported Mar 14 2014 - Updated Mar 14 2014 - 1 reports

CCR2 Gene Deletion and Pharmacologic Blockade Ameliorate a Severe Murine Experimental Autoimmune Neuritis Model of Guillain-Barré Syndrome

The molecular determinants and signaling pathways responsible for hematogenous leukocyte trafficking during peripheral neuroinflammation are incompletely elucidated. Chemokine ligand/receptor pair CCL2/CCR2 has been pathogenically implicated in the acute ... [Published PLoS medicine - Mar 14 2014]
First reported Feb 01 2014 - Updated Feb 01 2014 - 1 reports

"Non-genetically engineered produce tax credit" legislation revealing the motives of the anti-GMO movement in Hawaii -- and the environment 'aint one of them.

HOUSE OF REPRESENTATIVESH.B. NO.2187TWENTY-SEVENTH LEGISLATURE, 2014STATE OF HAWAIIA BILL FOR AN ACTRELATING TO TAXATION.BE IT ENACTED BY THE LEGISLATURE OF THE STATE OF HAWAII:     SECTION 1.  Chapter 235, Hawaii Revised Statutes, is amended by adding ... [Published GMO Pundit a.k.a. David Tribe - Feb 01 2014]
Entities: Anti-GMO, Agriculture, Taxes

Quotes

The following quote was obtained by the news editors from the background information supplied by the inventors: "Protein A is a 40,000 Da glycoprotein extracted from the cell wall of various bacteria. Bacteria use PA as a targeting and binding site for tissue attachment. Protein A has a high affinity for the Fc portion of certain immunoglobulin classes and even higher affinity for those immunoglobulins once they have bound antigen. This biochemical property of PA has been used in a large number of applications. These applications of PA reflect a use of the Fc binding properties of the molecule or PA's ability to stimulate humoral immunity in the absence of specific antigen induction (Superantigen applications)."

More Content

All (15) | News (12) | Reports (0) | Blogs (2) | Audio/Video (0) | Fact Sheets (1) | Press Releases (0)
sort by: Date | Relevance
PROTALEX : "Protein a Compositions and Methods ... [Published 4 Traders - Apr 16 2014]
Identification of Novel Genomic Aberrations in ... [Published PLoS medicine - Apr 13 2014]
Biology Maybe Right, Chemistry Ridiculously Wrong [Published In the Pipeline - Apr 11 2014]
Medical News Today: Scientists find link betwee... [Published Medical News Today - Apr 09 2014]
BACE1 ([small beta]-secretase) inhibitors for t... [Published RSC - Apr 02 2014]
NAI Alumni Seminar Series: Hopanoid Biosynthesi... [Published SpaceRef - Apr 02 2014]
FAT10 Gene Linked To Fat And Aging In Mice: Cou... [Published Medical Daily - Mar 24 2014]
Selection of Higher Order Regression Models in ... [Published PLoS medicine - Mar 23 2014]
Underlying Mechanism of Antimicrobial Activity ... [Published PLoS medicine - Mar 23 2014]
Ovalbumin-induced experimental allergic asthma ... [Published IngentaConnect Publication AAP - Mar 21 2014]
Could APP, Not Aβ, Explain Epileptic Activity i... [Published Alzheimer Research Forum - Mar 15 2014]
Monocyte Chemoattractant Protein-1 (MCP-1) Regu... [Published PLoS medicine - Mar 14 2014]
CCR2 Gene Deletion and Pharmacologic Blockade A... [Published PLoS medicine - Mar 14 2014]
"Non-genetically engineered produce tax credit"... [Published GMO Pundit a.k.a. David Tribe - Feb 01 2014]
Fact Sheet for genOway [Published Able2Act - Mar 28 2008]
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sort by: Date | Relevance
Biology Maybe Right, Chemistry Ridiculously Wrong [Published In the Pipeline - Apr 11 2014]
A reader sent along a puzzled note about this paper that's out in Science . It's from a large multicenter team (at least nine departments across the US, Canada, and Europe), and it's an ambitious effort to profile 3250 small molecules in a broad chemogenomics ...
"Non-genetically engineered produce tax credit"... [Published GMO Pundit a.k.a. David Tribe - Feb 01 2014]
HOUSE OF REPRESENTATIVESH.B. NO.2187TWENTY-SEVENTH LEGISLATURE, 2014STATE OF HAWAIIA BILL FOR AN ACTRELATING TO TAXATION.BE IT ENACTED BY THE LEGISLATURE OF THE STATE OF HAWAII:     SECTION 1.  Chapter 235, Hawaii Revised Statutes, is amended by adding ...
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