Hazard Ratio

Type: Keyphrase
Name: Hazard Ratio
First reported Aug 28 2014 - Updated Aug 28 2014 - 1 reports

Association of Nucleos(t)ide Analogue Therapy With Reduced Risk of Hepatocellular Carcinoma in Patients With Chronic Hepatitis B-A Nationwide Cohort Study

"In conclusion, nucleos(t)ide analogue use is associated with reduced risk of HCC in CHB patients. Age, sex, liver cirrhosis, and diabetes mellitus modify this association. More studies are needed to explore the wider use of nucleos(t)ide analogues for ... [Published National AIDS Treatment Advocacy Project - Aug 28 2014]
First reported Aug 28 2014 - Updated Aug 28 2014 - 1 reports

Long-Term Prognosis of Patients with Carbon Monoxide Poisoning: A Nationwide Cohort Study

by Chien-Cheng Huang, Min-Hsien Chung, Shih-Feng Weng, Chih-Chiang Chien, Shio-Jean Lin, Hung-Jung Lin, How-Ran Guo, Shih-Bin Su, Chien-Chin Hsu, Chi-Wen JuanBackgroundCarbon monoxide poisoning (COP) often produces severe complications and can be fatal. ... [Published Plosone.org - Aug 28 2014]
First reported Aug 25 2014 - Updated Aug 25 2014 - 1 reports

Analytic strategy can cut bias in large observational studies

(HealthDay)—In multicenter observational studies, bias from variability in treatment selection between clinical centers can be reduced by matching recalibrated propensity scores within clinical centers, according to a study published online Aug. 12 in ... [Published Medical Xpress - Aug 25 2014]
First reported Aug 25 2014 - Updated Aug 25 2014 - 1 reports

A Molecular Prognostic Model Predicts Esophageal Squamous Cell Carcinoma Prognosis

by Hui-Hui Cao, Chun-Peng Zheng, Shao-Hong Wang, Jian-Yi Wu, Jin-Hui Shen, Xiu-E Xu, Jun-Hui Fu, Zhi-Yong Wu, En-Min Li, Li-Yan XuBackgroundEsophageal squamous cell carcinoma (ESCC) has the highest mortality rates in China. The 5-year survival rate of ... [Published Plosone.org - Aug 25 2014]
First reported Aug 25 2014 - Updated Aug 25 2014 - 1 reports

Osteoporosis frailty index may predict health risks in women

The frailty index was a predictor of falls, fractures, overnight hospitalization and death in women with osteoporosis, according to study results.Researchers culled data on 3,985 women older than 55 years enrolled in the Hamilton Cohort of the Global ... [Published Orthopedics Today - Aug 25 2014]
Entities: Osteoporosis, Index, Risk
First reported Aug 22 2014 - Updated Aug 23 2014 - 1 reports

Deletion predicts survival in advanced non-small cell lung cancer

PUBLIC RELEASE DATE: 22-Aug-2014DENVER – Bcl-2-like protein 11 (BIM) deletion in advanced non-small cell lung cancer (NSCLC) is associated with shorter progression free survival (PFS) in epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor ... [Published EurekAlert! - Aug 22 2014]
First reported Aug 21 2014 - Updated Aug 21 2014 - 1 reports

Study design implications of death and hospitalization as endpoints in idiopathic pulmonary fibrosis

Background:   The feasibility of an interventional clinical trial in idiopathic pulmonary fibrosis (IPF) using death and hospitalization as primary endpoints is an area of uncertainty. This manuscript aims to illustrate the impact of cohort enrichment ... [Published CHEST - Aug 21 2014]
First reported Aug 21 2014 - Updated Aug 21 2014 - 1 reports

Treatments for Idiopathic Pulmonary Fibrosis

Dr. King and colleagues reply: Ohkubo and colleagues inquire about acute exacerbations of idiopathic pulmonary fibrosis. In the ASCEND trial, we did not evaluate acute exacerbations because of the challenges associated with its diagnosis 1 and the low ... [Published New England Journal of Medicine - Aug 21 2014]
First reported Aug 14 2014 - Updated Aug 14 2014 - 1 reports

One-Time Sigmoidoscopy Cuts Colorectal Cancer Recurrence

Share this article:Screening, with or without fecal occult blood testing, tied to reduced CRC versus no screening.Once-only flexible sigmoidoscopy screening, with or without fecal occult blood testing (FOBT), is associated with reduced colorectal cancer ... [Published Chemotherapy Advisor - Aug 14 2014]
First reported Aug 10 2014 - Updated Aug 10 2014 - 1 reports

Psychiatric problems are more common in MSers

Brenner P et a. Psychiatric diagnoses, medication and risk for disability pension in multiple sclerosis patients; a population-based register study. PLoS One. 2014 Aug 5;9(8):e104165. doi: 10.1371/journal.pone.0104165. eCollection 2014. Background:Psychiatric ... [Published Multiple Sclerosis Research - Aug 10 2014]
First reported Aug 10 2014 - Updated Aug 10 2014 - 2 reports

Optimal starting point for antiretroviral HIV treatment in a town in Cameroon: a randomised ...

Optimal starting point for antiretroviral treatment (ART) has been uncertain.Methods: Parallel group, single blind, randomised controlled study of adult HIV positive patients consulting at the Protestant Hospital, Ngaoundere, Cameroon in 2007-8. Simple ... [Published 7thSpace - Aug 10 2014]
First reported Aug 07 2014 - Updated Aug 07 2014 - 1 reports

An approach to trial design and analysis in the era of non-proportional hazards of the treatment ...

Most randomized controlled trials with a time-to-event outcome are designed and analysed under theproportional hazards assumption, with a target hazard ratio for the treatment effect in mind. However,the hazards may be non-proportional.We address how ... [Published 7thSpace - Aug 07 2014]

Quotes

"Iron deficiency has recently been reported as a frequent co-morbidity in heart failure and has been associated with impaired functional capacity, poor quality of life, and increased mortality, irrespective of the presence of anaemia. Therefore, correction of iron deficiency itself should be considered an attractive therapeutic target in this population."
Findings from the PARADIGM-HF trial, published simultaneously in the New England Journal of Medicine, "are extraordinarily powerful and compelling; they are destined to change the management of patients with chronic heart failure for years to come" said Milton Packer, MD, co-primary author of the study from University of Texas Southwestern Medical Center, in Dallas, Texas USA
"The main take-home points are that a simple set of predictors can identify those with type 1 diabetes who are at the greatest risk for all the major"
...E Clarson, MBChB, from the ResearchResearch Institute for Primary Care & Health Sciences at Keele University in the United Kingdom, and colleagues. "Although gout is traditionally thought of as an intermittent inflammatory condition, recent ultrasound studies have identified persistent subclinical inflammation in the intercritical period between acute attacks. It has been hypothesised that the combination of persistent inflammation and hyperuricaemia may potentiate or synergise CHD development."

More Content

All (327) | News (294) | Reports (0) | Blogs (33) | Audio/Video (0) | Fact Sheets (0) | Press Releases (0)
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Novartis drug shows promise on heart failure [Published Boston Globe - 58 mins ago]
New heart failure drug shows promise [Published Minneapolis Star Tribune - 4 hours ago]
Intravenous iron supplement can improve quality... [Published News-Medical.Net - 15 hours ago]
Investigational LCZ696 drug: A real breakthroug... [Published News-Medical.Net - 15 hours ago]
Model Predicts Complications in Type 1 Diabetes [Published General Medicine eJournal - Aug 29 2014]
Gout Linked to Increased Vascular Disease Risk [Published Diabetes Care - Aug 29 2014]
Risks of Antiepileptic Drugs During Pregnancy [Published General Medicine eJournal - Aug 29 2014]
Diabetes update: Key research at 2014 ADA meeting [Published Pharmacist.com - Aug 29 2014]
Study suggests contaminated blood cultures cont... [Published IVTEAM - Aug 29 2014]
Vaccine boosts advanced NSCLC patient survival [Published News-Medical.Net - Aug 28 2014]
Stereotactic radiosurgery feasible for multiple... [Published News-Medical.Net - Aug 28 2014]
Association of Nucleos(t)ide Analogue Therapy W... [Published National AIDS Treatment Advocacy Project - Aug 28 2014]
Ablynx's (ABLYF) CEO Edwin Moses on Q2 2014 Res... [Published Seeking Alpha - Aug 28 2014]
[18F]-Fluorodeoxyglucose Positron Emission Tomo... [Published Plosone.org - Aug 28 2014]
Long-Term Prognosis of Patients with Carbon Mon... [Published Plosone.org - Aug 28 2014]
The Long-Term Consequences of Preeclampsia [Published Theheart.org - Aug 28 2014]
Mortality of HIV patients in the ICU [Published Critical Care - Aug 28 2014]
Study Data from Chi-Mei Medical Center Update K... [Published 4 Traders - Aug 28 2014]
Long-term Risks for Kidney Donors [Published Theheart.org - Aug 28 2014]
Prognostic Value of Epidermal Growth Factor Rec... [Published Plosone.org - Aug 27 2014]
Contaminated Heparin and Outcomes after Cardiac... [Published Plosone.org - Aug 27 2014]
Which Cancer Patients Should Have Ovary Cryopre... [Published Diabetes Care - Aug 27 2014]
Vision problems for older adults can dim life e... [Published Health Canal - Aug 27 2014]
Genentech receives FDA approval for cervical ca... [Published Individual.com - Aug 27 2014]
Is UK obesity fuelling an increase in 10 cancers? [Published Nursing Times - Aug 27 2014]
Quantifying late gadolinium enhancement on CMR ... [Published 7thSpace - Aug 27 2014]
Enzalutamide for Patients with Metastatic Castr... [Published Chemotherapy Advisor - Aug 26 2014]
No Anticoagulation Option for VTE Prevention? T... [Published General Medicine eJournal - Aug 26 2014]
Vitamin D Deficiency and Rituximab-Mediated Cyt... [Published American Journal of Public Health - Aug 26 2014]
Aspirin Treatment and Outcomes After Percutaneo... [Published Journal of the American College of Cardiology - Aug 26 2014]
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Blogs

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Study: Use of methylphenidate-based ADHD medica... [Published SharpBrains - Aug 20 2014]
ADHD medication enhances the risk of heart problems in children (Science Nordic): “The risk of developing heart problems is twice as big for children taking medicine for Attention Deficit-Hyperactivity Disorder (ADHD) when compared to children not ...
Evidence and colorectal screening policy: a mis... [Published The Incidental Economist (Posts) - Aug 14 2014]
From JAMA, “ Effect of Flexible Sigmoidoscopy Screening on Colorectal Cancer Incidence and Mortality “: Importance: Colorectal cancer is a major health burden. Screening is recommended in many countries. Objective: To estimate the effectiveness of ...
Psychiatric problems are more common in MSers [Published Multiple Sclerosis Research - Aug 10 2014]
Brenner P et a. Psychiatric diagnoses, medication and risk for disability pension in multiple sclerosis patients; a population-based register study. PLoS One. 2014 Aug 5;9(8):e104165. doi: 10.1371/journal.pone.0104165. eCollection 2014. Background:Psychiatric ...
Takeda Receives Positive CHMP Opinions for Labe... [Published Nycomed News RSS feed - Jul 29 2014]
ZURICH, July 29, 2014 – Takeda Pharmaceuticals International GmbH (“Takeda”) today announced that the Committee for Medicinal Products for Human Use (CHMP) of the European Medicines Agency (EMA) has issued positive opinions for updates ...
A Biotech Stock Is Up Nearly 300% After Announc... [Published Clusterstock - Jul 23 2014]
Shares of Puma Biotechnology are up 296% right now. On Tuesday evening, the company announced encouraging results from its recent breast cancerdrug  trial. "[A] clinical trial of its experimental drug blocked the return of breast cancer in women ...
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