immunomodulation

Entity type image
Type: Keyphrase
Name: immunomodulation
First reported May 08 2013 - Updated May 08 2013 - 1 reports

UPDATE 1-Actelion gets go-ahead to continue new drug trial

* Selexipag is new drug for pulmonary arterial hypertension* Final results due by mid 2014* Actelion looking for alternatives to main drug Tracleer (Adds details, background)ZURICH, May 8 (Reuters) - Actelion should continue a late-stage study into a ... [Published Reuters - May 08 2013]
First reported May 08 2013 - Updated May 08 2013 - 1 reports

Combined Donor Simvastatin and Methylprednisolone Treatment Prevents Ischemia-Reperfusion Injury in Rat Cardiac Allografts Through Vasculoprotection and Immunomodulation

Background: Ischemia-reperfusion injury (IRI) and allograft dysfunction remain as two of the major clinical challenges after heart transplantation. Here, we investigated the effect of donor treatment with simvastatin and methylprednisolone on microvascular ... [Published Transplantation - May 08 2013]
First reported Apr 25 2013 - Updated Apr 25 2013 - 1 reports

Drug Research: Data from University Medical Center Provide New Insights into Drug Research

Today's Medical & Research NewsDrug Research2013 APR 25 -- By a News Reporter-Staff News Editor at Biotech Week -- Investigators publish new report on Drug Research. According to news reporting originating in Groningen, Netherlands, by NewsRx journalists, ... [Published NewsRX - Apr 25 2013]
First reported Apr 19 2013 - Updated Apr 19 2013 - 1 reports

Findings from University of Ulm Provides New Data about Orthopedics

(NewsRx) -- By a News Reporter-Staff News Editor at Health & Medicine Week -- Current study results on Orthopedics have been published. According to news reporting out of Ulm, Germany, by NewsRx editors, research stated, "Confirming clinical evidence, ... [Published NewsRX - Apr 19 2013]

Quotes

According to the news editors, the research concluded: "These data support the safety and efficacy of the MRI tracer for clinical tracking of human stem cells."
According to the news editors, the research concluded: "These findings suggest that the CD4 T cell-mediated masking effects of the immunogenicity of tumor-associated antigens are qualitatively and quantitatively different depending on the individual antigens."
Thirdly, it has been taught that non-neuronal cells are less sensitive to botulinum toxin (US 2005/0031648 at para 191) and that, "as the toxin concentration is raised, non-cholinergic sympathetic neurons, chromaffin cells and other cell types can take up a botulinum toxin and show reduced exocytosis." It is well known to one skilled in the art that injections of higher concentrations of toxin are associated with a higher incidence of local side effects...
"In a further aspect, the invention provides any of the methods described herein, wherein said CTLA4 antagonist is administered in combination with an IL-6 antagonist (i e. an agent that results in IL-6 blockade). In some embodiments, said IL-6 antagonist is administered prior to the CTLA4 antagonist. In some embodiments, the IL-6 antagonist is administered, and then a CTLA4 antagonist is administered if the serum CRP concentration is determined to be less than an amount that is from 1 to 2 times the upper limit of normal as determined by an assay method used to measure the serum CRP concentration. In one embodiment, such amount is 2.0, 1.9, 1.8, 1.7, 1.6, 1.5, 1.4, 1.3, 1.2, 1.1, or 1.0 times the upper limit of normal as determined by an assay method used to measure the serum CRP concentration. In one embodiment, said IL-6 antagonist is an anti-IL-6 antibody, or antigen-binding portion thereof. In another embodiment, said IL-6 antagonist is an anti-IL-6 receptor antibody or antigen-binding portion thereof."

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All (25) | News (22) | Reports (1) | Blogs (1) | Audio/Video (0) | Fact Sheets (0) | Press Releases (1)
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Potent Suppression of Kv1.3 Potassium Channel a... [Published Elites TV - 14 hours ago]
Stem Cell Research: Researchers at Department o... [Published NewsRX - May 20 2013]
Immunization: Study Results from Kyushu Univers... [Published NewsRX - May 20 2013]
Treating neoplasms with neurotoxin [Published PharmCast - May 19 2013]
Medicinal Mushrooms: Natural Supplement for Dia... [Published Positive Health - May 16 2013]
Patent Issued for Cancer Treatment [Published Equities.com - May 15 2013]
U.S. Patents Awarded to Inventors in New Jersey... [Published Equities.com - May 11 2013]
AASTROM BIOSCIENCES INC - 10-Q - Management's D... [Published Pharmacy Choice - May 09 2013]
UPDATE 1-Actelion gets go-ahead to continue new... [Published Reuters - May 08 2013]
Combined Donor Simvastatin and Methylprednisolo... [Published Transplantation - May 08 2013]
Melanomas: Ludwig presents advancements in immu... [Published NewsRX - Apr 27 2013]
SCYNEXIS Presents SCY-635 Data on HCV at Intern... [Published Business Wire - Apr 25 2013]
Active Biotech and Ipsen update the analysis pl... [Published Live-PR.com - Apr 25 2013]
Drug Research: Data from University Medical Cen... [Published NewsRX - Apr 25 2013]
Findings from University of Ulm Provides New Da... [Published NewsRX - Apr 19 2013]
The Tricky Business of Treating Massive Hemorrhage [Published Pharmacy Practice News - Apr 18 2013]
What Will It Take For Stem Cell Companies To Cl... [Published Seeking Alpha - Apr 17 2013]
Investing in Biotech Stem Cell Research Companies [Published Market Oracle - Apr 17 2013]
Genomic Sequence and Virulence of Clonal Isolat... [Published Elites TV - Apr 15 2013]
Ringing Cedars Oil Natural Treatment for Gastro... [Published PRWeb - Apr 01 2013]
Research and Markets: Transfusion Therapy: Clin... [Published Yahoo! Finance - Mar 11 2013]
Rituximab for Chronic Fatigue Syndrome: Jumping... [Published Science-Based Medicine - Jan 08 2013]
Immunosuppressive polypeptides and nucleic acids [Published PharmCast - Oct 25 2012]
Inhibitors of TGF-R signaling for treatment of ... [Published PharmCast - Oct 21 2012]
Chimeric immunomodulatory compounds and methods... [Published PharmCast - Aug 03 2012]
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Rituximab for Chronic Fatigue Syndrome: Jumping... [Published Science-Based Medicine - Jan 08 2013]
Now that the XMRV myth has been put to rest ,  patients with Chronic Fatigue Syndrome (CFS) are no longer jumping the gun  to demand anti-retroviral treatments. But they are jumping the gun in new ways, based on very preliminary data coming out of ...
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SCYNEXIS Presents SCY-635 Data on HCV at Intern... [Published Business Wire - Apr 25 2013]
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