immunomodulation

Type: Keyphrase
Name: immunomodulation
First reported Oct 08 2014 - Updated Oct 08 2014 - 1 reports

Enhancing immunomodulation on innate immunity by shape transition among RNA triangle, square and pentagon nanovehicles

Modulation of immune response is important in cancer immunotherapy, vaccine adjuvant development and inflammatory or immune disease therapy. Here we report the development of new immunomodulators via control of shape transition among RNA triangle, square ... [Published Bionity.com - Oct 08 2014]
First reported Oct 07 2014 - Updated Oct 07 2014 - 1 reports

Genetically Engineered Lactococcus lactis Protect against House Dust Mite Allergy in a BALB/c Mouse Model

by Chunqing Ai, Qiuxiang Zhang, Chengcheng Ren, Gang Wang, Xiaoming Liu, Fengwei Tian, Jianxin Zhao, Hao Zhang, Yong Q. Chen, Wei ChenBackgroundMucosal vaccine based on lactic acid bacteria is an attractive concept for the prevention and treatment of ... [Published Plosone.org - Oct 07 2014]
First reported Oct 07 2014 - Updated Oct 07 2014 - 1 reports

Global Tissue Engineering and Organ Regeneration Market - Global Industry Analysis and Forecast to 2019

Albany, NY -- (SBWIRE) -- 10/07/2014 -- Tissue engineering and organ regeneration market encompasses those products used in medicine. The application of these new age biomaterials include burn treatment or wound care, orthopaedics, urological products, ... [Published Reliance Trust - Oct 07 2014]
First reported Oct 04 2014 - Updated Oct 04 2014 - 1 reports

Paricalcitol Reduces Peritoneal Fibrosis in Mice through the Activation of Regulatory T Cells and Reduction in IL-17 Production

by Guadalupe T. González-Mateo, Vanessa Fernández-Míllara, Teresa Bellón, Georgios Liappas, Marta Ruiz-Ortega, Manuel López-Cabrera, Rafael Selgas, Luiz S. AroeiraFibrosis is a significant health problem associated with a chronic inflammatory reaction. ... [Published Plosone.org - Oct 04 2014]
First reported Oct 01 2014 - Updated Oct 01 2014 - 1 reports

Adoption of stem cell therapy is driving growth in the global regenerative medicine market

Regenerative medicines have the unique ability to repair, replace and regenerate tissues and organs, affected due to some injury, disease or due to natural aging process.Posted via Industry Today. Are you into it? Follow us on Twitter @IndustryTodayAdvancement ... [Published Industry Today - Oct 01 2014]
First reported Sep 27 2014 - Updated Sep 27 2014 - 1 reports

Influenza Vaccination of Pregnant Women and Protection of Their Infants

Pregnant women are designated as a priority group for seasonal influenza vaccination by the World Health Organization (WHO)1 because of their heightened susceptibility to severe influenza from the second trimester to the early postpartum period.2,3 Since ... [Published NEJM Articles Most Widely Covered in the Press - Sep 27 2014]
First reported Sep 24 2014 - Updated Sep 25 2014 - 2 reports

Research Data from Revivicor Update Understanding of Xenografts (Genetically engineered pigs and target-specific immunomodulation provide significant...

Research Data from Revivicor Update Understanding of Xenografts (Genetically engineered pigs and target-specific immunomodulation provide significant graft survival and hope for clinical cardiac xenotransplantation) By a News Reporter-Staff News Editor ... [Published Town Hall - Sep 25 2014]
First reported Sep 23 2014 - Updated Sep 23 2014 - 1 reports

YopM as delivery vehicle for cargo molecules and as biological therapeutic for immunomodulation of inflammatory reactions

The present invention relates to the use of Yersinia outer protein M (YopM), a YopM fragment, or a YopM variant, which is capable of autopenetrating the cell membrane and of integrating into the cell cytosol without the requirement of additional factors ... [Published Free Patents Online - Sep 23 2014]
First reported Sep 18 2014 - Updated Sep 18 2014 - 1 reports

Connecting the Lab and the Clinic in Regenerative Medicine

An interview with the director of the Translational Tissue Engineering Center at Johns Hopkins University School of Medicine can be found at the Methuselah Foundation blog : We named it the Translational Tissue Engineering Center because we're focused ... [Published Fight Aging! - Sep 18 2014]
First reported Sep 17 2014 - Updated Sep 17 2014 - 2 reports

Researchers from University of Wisconsin Detail Findings in Stem Cells (Biomaterial-Mesenchymal Stem Cell Constructs for Immunomodulation in...

Researchers from University of Wisconsin Detail Findings in Stem Cells (Biomaterial-Mesenchymal Stem Cell Constructs for Immunomodulation in Composite Tissue Engineering) (Biomaterial-Mesenchymal Stem Cell Constructs for Immunomodulation in ...) By a ... [Published Wall Street Business Network - Sep 17 2014]
First reported Sep 15 2014 - Updated Sep 15 2014 - 1 reports

Form: Non-technical summaries granted during 2013: volume 37

The following projects are listed in volume 37 of 2013:cortical networks underlying primate choice (covering prefrontal cortex, neuronal networks, electrophysiology, lesions, non-human primate) physician aided reconstitution of immune system (covering ... [Published HM Treasury - Sep 15 2014]
First reported Sep 04 2014 - Updated Sep 05 2014 - 1 reports

Influenza Vaccination of Pregnant Women and Protection of Their Infants

Pregnant women are designated as a priority group for seasonal influenza vaccination by the World Health Organization (WHO) because of their heightened susceptibility to severe influenza from the second trimester to the early postpartum period. Since ... [Published The New England Journal of Medicine: Obstetrics ... - Sep 04 2014]

Quotes

"We don't have oral cladribine, but that doesn't mean to say you can't use it. What we are suggesting is going back to the subcutaneous formulation that is licensed for treating hairy cell leukaemia. I have uploaded the Royal London Hospital's protocol for your information. We tend to use it patients with relapsing secondary-progressive disease who have failed other therapies, for whom we don't have a licensed therapy. However, in resource poor countries and environments where you can't access licensed DMTs I would use it in active MSers as a first second or third line therapy. It is clear from the CIS or ORACLE study that the sooner you use cladribine the better the outcome. The main safety signal is infection, particularly herpes infections and low white blood counts. For the herpes infections you need to be vigilant and treat them with anti-virals. In subjects who are seronegative for VZV (varicella-zoster virus) they should be vaccinated against the virus before starting cladribine. In countries with a high background rate of tuberculosis it is important to screen for, and exlcude ative or latent, TB infection. The lymphopaenia (low lymphocyte counts) can be managed by strict redosing guidelines. Please note I would suggest using cladribine as we use alemtuzumab, i e. as an induction agent. I would only give two years of treatment and then monitor to see if there is any breakthrough disease before administering further courses."
"In recent years, with a focus on the above-described functions of NKT cells, a therapeutic drug of cancer, which contains .alpha.-GalCer as an active ingredient, has been developed. However, NKT cells activated by the administration of .alpha.-GalCer produce IFN-.gamma., which is a cytokine useful for the cancer treatment and inducing immunostimulatory activity, as well as simultaneously produce IL-4, which is a cytokine inducing an immunosuppressive action. As a result, the effects of both are cancelled each other, posing the problem of a lack of effect on cancer treatment."

More Content

All (43) | News (36) | Reports (0) | Blogs (6) | Audio/Video (0) | Fact Sheets (0) | Press Releases (1)
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OffLabel: cladribine [Published Multiple Sclerosis Research - Oct 19 2014]
Patent Issued for Synthetic Glycolipid and Use [Published 4 Traders - Oct 15 2014]
Avian Influenza. The use of herbal antivirals a... [Published Engormix.com - Oct 14 2014]
Feel great all summer long [Published All4Women - Oct 14 2014]
Differential Expression of Collectins in Human ... [Published Plosone.org - Oct 10 2014]
Enhancing immunomodulation on innate immunity b... [Published Bionity.com - Oct 08 2014]
Acacetin Blocks Kv1.3 Channels and Inhibits Hum... [Published Sexual Development - Oct 07 2014]
Genetically Engineered Lactococcus lactis Prote... [Published Plosone.org - Oct 07 2014]
Global Tissue Engineering and Organ Regeneratio... [Published Reliance Trust - Oct 07 2014]
Immunotoxicology Research Fellow [Published PharmaDiversity - Oct 07 2014]
Big Risk, Big Reward In This Biotech [Published Seeking Alpha - Oct 06 2014]
Molecular Immunotoxicology [Published Research and Markets - Oct 04 2014]
Paricalcitol Reduces Peritoneal Fibrosis in Mic... [Published Plosone.org - Oct 04 2014]
Nutraceuticals International Group ~ NaturSYN Line [Published Natural Products Industry Insider - Oct 02 2014]
Adoption of stem cell therapy is driving growth... [Published Industry Today - Oct 01 2014]
Influenza Vaccination of Pregnant Women and Pro... [Published NEJM Articles Most Widely Covered in the Press - Sep 27 2014]
Meta-analysis: anti-TNF therapy deemed safe for... [Published Medical Xpress - Sep 26 2014]
Research Data from Revivicor Update Understandi... [Published Town Hall - Sep 25 2014]
Research Data from Revivicor Update Understandi... [Published HispanicBusiness.com - Sep 24 2014]
Investigators at Multiple Sclerosis Research Ce... [Published HispanicBusiness.com - Sep 24 2014]
YopM as delivery vehicle for cargo molecules an... [Published Free Patents Online - Sep 23 2014]
DBV Technologies Announces Primary Endpoint Met... [Published BusinessWeek - Sep 22 2014]
Blood Transfusions & Infection Risk [Published Physicians Weekly - Sep 19 2014]
Connecting the Lab and the Clinic in Regenerati... [Published Fight Aging! - Sep 18 2014]
Curie-Cancer, Inventiva partners in epigenetics... [Published Center Watch - Sep 18 2014]
Researchers from University of Wisconsin Detail... [Published Wall Street Business Network - Sep 17 2014]
Researchers from University of Wisconsin Detail... [Published HispanicBusiness.com - Sep 17 2014]
NEKTAR THERAPEUTICS : Patent Issued for Oligome... [Published 4 Traders - Sep 17 2014]
Risk Factors for Surgical Site Infection Follow... [Published Journal of Bone and Joint Surgery - Sep 17 2014]
HDL Cholesterol and CVD Mortality in Hemodialys... [Published General Medicine eJournal - Sep 17 2014]
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Blogs

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OffLabel: cladribine [Published Multiple Sclerosis Research - Oct 19 2014]
Cladribine is my fourth off label DMT for treating MS in resource poor environments. #MSBlog #MSResearch #OffLabel "This post is the fourth in a series of posts to try and help neurologists who treat MS in healthcare environments where they cannot access ...
Influenza Vaccination of Pregnant Women and Pro... [Published NEJM Articles Most Widely Covered in the Press - Sep 27 2014]
Pregnant women are designated as a priority group for seasonal influenza vaccination by the World Health Organization (WHO)1 because of their heightened susceptibility to severe influenza from the second trimester to the early postpartum period.2,3 Since ...
Connecting the Lab and the Clinic in Regenerati... [Published Fight Aging! - Sep 18 2014]
An interview with the director of the Translational Tissue Engineering Center at Johns Hopkins University School of Medicine can be found at the Methuselah Foundation blog : We named it the Translational Tissue Engineering Center because we're focused ...
Influenza Vaccination of Pregnant Women and Pro... [Published The New England Journal of Medicine: Obstetrics ... - Sep 04 2014]
Pregnant women are designated as a priority group for seasonal influenza vaccination by the World Health Organization (WHO) because of their heightened susceptibility to severe influenza from the second trimester to the early postpartum period. Since ...
[Editorial] Skin cancer: prevention is better t... [Published The Lancet - Aug 08 2014]
Skin cancer is now the most commonly diagnosed cancer in the USA with about 5 million people treated every year. In Germany, the Federal Statistics Bureau reported last week that treatment for skin cancer in hospital has risen more than that for any other ...
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Press Releases

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Scientific guideline: Draft concept paper on gu... [Published EMA Ongoing public consultations - Aug 01 2014]
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