lysosome

Type: Keyphrase
Name: lysosome
First reported 3 hours ago - Updated 3 hours ago - 1 reports

FDA Hosts Drug Development Meeting for Neurologic Manifestations of Inborn Metabolism Errors

The FDA will listen to real-world experiences of patients living with metabolic diseases such as phenylketonuria, Wilson’s disease and lysosomal storage disorders at a June 10 meeting on patient-focused drug development for neurologic manifestations of ... [Published FDA News - 3 hours ago]
First reported Apr 23 2014 - Updated Apr 23 2014 - 1 reports

How Cells Take Out the Trash

Autophagy consists of a collection of cellular housecleaning processes responsible for recycling damaged cellular components. It is known to relate to longevity, as demonstrated in numerous animals studies in which aging is slowed via genetic or ... [Published Fight Aging! - Apr 23 2014]
First reported Apr 23 2014 - Updated Apr 23 2014 - 1 reports

TFE3 Promotes Autophagy

Autophagy is the name given to a collection of processes that recycle damaged cellular components and unwanted or harmful molecules. Materials flagged for recycling are engulfed by one of the cell's lysosomes and then dismantled inside it. Greater ... [Published Fight Aging! - Apr 23 2014]
First reported Apr 21 2014 - Updated Apr 22 2014 - 2 reports

How Cells Take Out the Trash

Contact InformationAvailable for logged-in reporters onlyNewswise — As people around the world mark Earth Day (April 22) with activities that protect the planet, our cells are busy safeguarding their own environment.To keep themselves neat, tidy and above ... [Published Newswise - Apr 22 2014]
Entities: lysosome, Protein, Enzyme, Cancer
First reported Apr 22 2014 - Updated Apr 22 2014 - 1 reports

Improved Reagents for Newborn Screening of Mucopolysaccharidosis Types I, II, and VI by Tandem Mass Spectrometry

Tandem mass spectrometry for the multiplex and quantitative analysis of enzyme activities in dried blood spots on newborn screening cards has emerged as a powerful technique for early assessment of lysosomal storage diseases. Here we report the design ... [Published Analytical Chemistry - Apr 22 2014]
First reported Apr 21 2014 - Updated Apr 21 2014 - 2 reports

Synageva BioPharma Release: LAL Deficiency Disease Review Published In Atherosclerosis

LEXINGTON, Mass.--(BUSINESS WIRE)--Synageva BioPharma Corp. (Synageva) (NASDAQ:GEVA), a biopharmaceutical company developing therapeutic products for rare diseases, today announced the publication of an overview of lysosomal acid lipase deficiency (LAL ... [Published BioSpace - Apr 21 2014]
First reported Apr 07 2014 - Updated Apr 07 2014 - 2 reports

Magnetized Nanoparticles Destroy Specific Cancer Cells

By Joel LindseyA team of researchers working at Lund University in Sweden is developing a cancer-fighting treatment that uses spinning nanoparticles to destroy cancer cells.“The clever thing about the technique is that we can target selected cells without ... [Published Medical Design Online - Apr 07 2014]
First reported Apr 03 2014 - Updated Apr 04 2014 - 4 reports

Nanoparticles cause cancer cells to self-destruct

Representational picture“The interesting thing about the technique is that we can target selected cells without harming surrounding tissue. There are many ways to kill cells, but this method is contained and remote controlled," said Professor Erik Renstrom ... [Published Jagran Post - Apr 04 2014]
First reported Mar 31 2014 - Updated Apr 01 2014 - 2 reports

Chemical Probe Profiles Organelle Activity

A team of scientists from Pacific Northwest National Laboratory synthesized a chemical activity-based probe (ABP) that can provide new information about how living cells function. The new ABP is designed to enter a living cell without interacting with ... [Published Laboratory Equipment - Apr 01 2014]
First reported Mar 28 2014 - Updated Mar 29 2014 - 2 reports

Repeated hUCB injections may improve prognosis of children with deadly inherited disorder

Putnam Valley, NY. (Mar. 28 2014) New insight has been gained into treating an inherited disorder that creates serious neurological and behavioral disabilities in children and usually leads to death in the teen years.In a recent study into the effects ... [Published Bio-Medicine - Mar 28 2014]
First reported Mar 27 2014 - Updated Mar 28 2014 - 2 reports

biOasis awarded patent allowances for Lysosomal Storage Disease therapeutic in Europe and Canada

Biopharmaceutical company biOasis Technologies (TSX VENTURE:BTI)(Other OTC:BIOAF) disclosed on Thursday the receipt of notices of allowance from the European and Canadian Patent offices for its patent application titled, "Use of P97 as an Enzyme Delivery ... [Published Individual.com - Mar 28 2014]
Entities: lysosome, Patent, Enzyme
First reported Mar 27 2014 - Updated Mar 27 2014 - 2 reports

Studies from Sapienza University Reveal New Findings on Biochemistry and Biophysics

By a News Reporter-Staff News Editor at Life Science Weekly -- Research findings on Life Science Research are discussed in a new report. According to news reporting from Rome, Italy, by NewsRx journalists, research stated, "Here we present a quantitative ... [Published HispanicBusiness.com - Mar 27 2014]

Quotes

...According to news originating from Dublin, Ireland , by NewsRx correspondents, research stated, "Nanoparticle properties, such as small size relative to large highly modifiable surface area, offer great promise for neuro-therapeutics and nanodiagnostics. A fundamental understanding and control of how nanoparticles interact with the blood-brain barrier (BBB) could enable major developments in nanomedical treatment of previously intractable neurological disorders, and help ensure that nanoparticles not intended to reach the brain do not cause adverse effects."
...Zeljko Reiner, M D , Director, University Hospital Center, School of Medicine, University of Zagreb, Zagreb, Croatia, and lead author of the study. "Since dyslipidemia is a common clinical manifestation of LAL Deficiency that is shared among other cardiovascular, liver and metabolic diseases and has been associated with accelerated development of atherosclerosis, cardiovascular disease and premature mortality, it is important that physicians remain vigilant to avoid mis- or under-diagnosing this disease. This review paper provides recommendations to lipidologists, endocrinologists, cardiologists, and hepatologists on how to recognize and definitively diagnose individuals with LAL Deficiency using a dried-blood spot test."
...According to news reporting out of Anhui , People's Republic of China , by NewsRx editors, research stated, "Polyphosphoesters with repeating phosphoester linkages in the backbone can be easily functionalized, are biodegradable and potentially biocompatible, and may be potential candidates as polymer carriers of drug conjugates. Here, the efficacy of a polyphosphoester drug conjugate as an anticancer agent in vivo is assessed for the first time."
...According to news originating from Rochester, Minnesota , by NewsRx correspondents, research stated, "The blood-brain barrier (BBB) presents a major challenge to effective treatment of neurological disorders, including lysosomal storage diseases (LSDs), which frequently present with life-shortening and untreatable neurodegeneration. There is considerable interest in methods for intravenous delivery of lysosomal proteins across the BBB but for the most part, levels achievable in the brain of mouse models are modest and increased lifespan remains to be demonstrated."

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All (238) | News (194) | Reports (0) | Blogs (39) | Audio/Video (0) | Fact Sheets (0) | Press Releases (4)
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FDA Hosts Drug Development Meeting for Neurolog... [Published FDA News - 3 hours ago]
Findings from University College Dublin Broaden... [Published HispanicBusiness.com - 9 hours ago]
The YXXPhi motif within the severe acute respir... [Published 7thSpace - 10 hours ago]
CNS Axons Globally Increase Axonal Transport af... [Published Journal of Neuroscience - 22 hours ago]
Synageva BioPharma Corp. Publishes LAL Deficien... [Published Individual.com - 22 hours ago]
Researchers' Work from University of Science an... [Published HispanicBusiness.com - Apr 24 2014]
Rare Diseases: From Newborns to Nonagenarians [Published General Medicine eJournal - Apr 23 2014]
How Cells Take Out the Trash [Published Fight Aging! - Apr 23 2014]
TFE3 Promotes Autophagy [Published Fight Aging! - Apr 23 2014]
Burot: The hidden beach paradise of Calatagan [Published Loqal - Apr 22 2014]
How Cells Take Out the Trash [Published Newswise - Apr 22 2014]
The Role of the Niemann-Pick Disease, Type C1 P... [Published PLoS medicine - Apr 22 2014]
E50K-OPTN-Induced Retinal Cell Death Involves t... [Published PLoS medicine - Apr 22 2014]
Improved Reagents for Newborn Screening of Muco... [Published Analytical Chemistry - Apr 22 2014]
BioMarin Pharmaceutical Down 19.0% Since SmarTr... [Published Comtex SmarTrend - Apr 22 2014]
Working to Remove the Heaps of Unburnable Cellu... [Published Fight Aging! - Apr 21 2014]
Synageva BioPharma Release: LAL Deficiency Dise... [Published BioSpace - Apr 21 2014]
Synageva announces publication of LAL Deficienc... [Published News-Medical.Net - Apr 21 2014]
LAL Deficiency Disease Review Published in Athe... [Published CNBC - Apr 21 2014]
LAL Deficiency Disease Review Published in Athe... [Published Business Wire Health News - Apr 21 2014]
Methods and compositions for treating brain dis... [Published PharmCast - Apr 21 2014]
Testosterone Therapy in Hypogonadal Men and LAM... [Published General Medicine eJournal - Apr 17 2014]
Airway Levels of YKL-40 Reflect Inflammation in CF [Published General Medicine eJournal - Apr 17 2014]
Researchers from Mayo Clinic Detail Findings in... [Published HispanicBusiness.com - Apr 17 2014]
New Findings from Massachusetts Institute of Te... [Published HispanicBusiness.com - Apr 17 2014]
Patent Issued for Methods and Compositions for ... [Published HispanicBusiness.com - Apr 16 2014]
New Transport Vesicles Findings from Tel Aviv U... [Published HispanicBusiness.com - Apr 16 2014]
Postdoctoral Fellow, Drug Safety Research & Dev... [Published PharmaDiversity - Apr 16 2014]
2014-2015 Genzyme/ACMG Foundation Medical Genet... [Published 4 Traders - Apr 16 2014]
QUIDEL : Patent Issued for Methods of Use for a... [Published 4 Traders - Apr 16 2014]
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Blogs

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How Cells Take Out the Trash [Published Fight Aging! - Apr 23 2014]
Autophagy consists of a collection of cellular housecleaning processes responsible for recycling damaged cellular components. It is known to relate to longevity, as demonstrated in numerous animals studies in which aging is slowed via genetic or ...
TFE3 Promotes Autophagy [Published Fight Aging! - Apr 23 2014]
Autophagy is the name given to a collection of processes that recycle damaged cellular components and unwanted or harmful molecules. Materials flagged for recycling are engulfed by one of the cell's lysosomes and then dismantled inside it. Greater ...
Working to Remove the Heaps of Unburnable Cellu... [Published Fight Aging! - Apr 21 2014]
Every cell in your body is a busy factory, constantly engaged in turning raw materials into complex proteins via the processes of gene expression , following the blueprints in your DNA . The source of much of the necessary supply of raw materials is ...
LAL Deficiency Disease Review Published in Athe... [Published Business Wire Health News - Apr 21 2014]
LEXINGTON, Mass.--(BUSINESS WIRE)--Synageva BioPharma Corp. (Synageva) (NASDAQ:GEVA), a biopharmaceutical company developing therapeutic products for rare diseases, today announced the publication of an overview of lysosomal acid lipase deficiency (LAL ...
BDP WEEK 2014: Antibody Drug Conjugates [Published Future of BioPharma - Apr 16 2014]
There was a heavy concentration of talks on antibody drug conjugates the last two days of BDP Week, so much so that the speakers soon started to either refer to the previous talks when relevant or promote an upcoming talk that was going to provide ...
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Press Releases

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Amicus Therapeutics Announces Presentations and... [Published GlobeNewswire: Acquisitions News - Jan 30 2014]
Ultragenyx Announces Initiation of Phase 1/2 St... [Published GlobeNewswire: Acquisitions News - Dec 04 2013]
BioMarin Stock Trading Halted Today [Published GlobeNewswire: Acquisitions News - Nov 19 2013]
FDA Posts Briefing Documents for Advisory Commi... [Published GlobeNewswire: Advertising News - Nov 15 2013]
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