macrophage

Type: Keyphrase
Name: macrophage
First reported 3 hours ago - Updated 3 hours ago - 1 reports

Fat Damages the Lungs of Heavy Drinkers

Alcohol causes fat build-up in the lungs of rats, impairing immune function and possibly explaining why alcoholics are more likely to develop lung disease(PHILADELPHIA) – Heavy drinking damages the body in many ways. In addition to liver failure, alcoholics ... [Published Health Canal - 3 hours ago]
First reported 15 hours ago - Updated 15 hours ago - 1 reports

Biomineralized Anisotropic Gold Microplate–Macrophage Interactions Reveal Frustrated Phagocytosis-like Phenomenon: A Novel Paclitaxel Drug Delivery Vehicle

ACS Applied Materials & Interfaces DOI: 10.1021/am5 ... [Published ACS Applied Materials & Interfaces - 15 hours ago]
First reported 20 hours ago - Updated 20 hours ago - 1 reports

SignaBlok Wins $1.34M NIH Phase II Grant to Advance New Nanotechnology for Atherosclerosis Imaging

- Jul. 29, 2014 - SHREWSBURY, Mass. -- SignaBlok, Inc., a Massachusetts-based emerging biopharmaceutical company, announced today the award of a Phase II Small Business Innovation Research (SBIR) grant by the National Heart Lung and Blood Institute (NHLBI), ... [Published Prlog - 20 hours ago]
First reported Jul 29 2014 - Updated Jul 29 2014 - 1 reports

Cytokine pathway disruption in a mouse model of schizophrenia induced by Munc18-1a overexpression ...

An accumulating body of evidence points to the significance of neuroinflammation and immunogenetics in schizophrenia, and an imbalance of cytokines in the central nervous system (CNS) has been suggested to be associated with the disorder. Munc18- overexpressing ... [Published 7thSpace - Jul 29 2014]
First reported Jul 28 2014 - Updated Jul 28 2014 - 1 reports

Macrophages derived from infiltrating monocytes mediate autoimmune myelin destruction

Insight from Michael HenekaMacrophages mediate myelin destruction in multiple sclerosis (MS), but the origin of these cells (whether derived from tissue-resident microglial cells or infiltrating monocytes) has been widely debated. Now, ... [Published Journal of Experimental Medicine - Jul 28 2014]
Entities: monocyte, macrophage, myelin
First reported Jul 28 2014 - Updated Jul 28 2014 - 1 reports

Ever Wondered How Tattoos Stay Permanent? [Video]

[embedded content]Related PostsHow do tattoos manage to stay on the skin even after all the abuse us humans put our bodies through? This is an interesting question that features an even more interesting answer that those with tattoos may not even kno ... [Published 2Oceans Vibe News - Jul 28 2014]
Entities: macrophage, Abuse
First reported Jul 25 2014 - Updated Jul 25 2014 - 1 reports

Differential responses of osteoblasts and macrophages upon Staphylococcus aureus infection

Staphylococcus aureus (S. aureus) is one of the primary causes of bone infections which are often chronic and difficult to eradicate.Bacteria like S. aureus may survive upon internalization in cells and may be responsible for chronic and recurrent in ... [Published 7thSpace - Jul 25 2014]
First reported Jul 25 2014 - Updated Jul 25 2014 - 1 reports

Targeting residual risk: a new approach to treating CVD?

July 2014 Br J Cardiol 2014;21:(3) doi: 10.5837/bjc.2014.023 Authors:Alan Begg, Iain FindlayLipoproteins play a pivotal role in the development of atherosclerosis, where apolipoprotein B-containing lipoproteins are considered pro-atherogenic and high-density ... [Published British Journal of Cardiology - Jul 25 2014]
First reported Jul 24 2014 - Updated Jul 24 2014 - 1 reports

Peripheral Glia Have a Pivotal Role in the Initial Response to Axon Degeneration of Peripheral Sensory Neurons in Zebrafish

by Holly M. Pope, Mark M. VoigtAxon degeneration is a feature of many peripheral neuropathies. Understanding the organismal response to this degeneration may aid in identifying new therapeutic targets for treatment. Using a transgenic zebrafish line expressing ... [Published Plosone.org - Jul 24 2014]
Entities: Axon, Zebrafish, Neuron
First reported Jul 23 2014 - Updated Jul 24 2014 - 3 reports

Biotron's HIV drug candidate reverses impaired immune system

Singapore: Australia based Biotron's HIV drug candidate BIT225 has demonstrated its ability to reverse HIV-induced impairment of the immune system in HIV-infected subjects.HIV infection causes immune activation and inflammation, which are associated with ... [Published Bio Spectrum Asia - Jul 24 2014]
First reported Jul 24 2014 - Updated Jul 24 2014 - 1 reports

AASTROM BIOSCIENCES : Patent Application Titled "Mesenchymal Stromal Cell Populations and Methods of Making Same" Published Online

By a News Reporter-Staff News Editor at Biotech Week -- According to news reporting originating from Washington, D.C. , by NewsRx journalists, a patent application by the inventors Zeigler, Frank ( Encinitas, CA ); Bartel, Ronnda L . ( San Diego, CA ), ... [Published 4 Traders - Jul 24 2014]
First reported Jul 23 2014 - Updated Jul 23 2014 - 1 reports

What macrophage does what?

Yamasaki R, Lu H, Butovsky O, Ohno N, Rietsch AM, Cialic R, Wu PM, Doykan CE, Lin J, Cotleur AC, Kidd G, Zorlu MM, Sun N, Hu W, Liu L, Lee JC, Taylor SE, Uehlein L, Dixon D, Gu J, Floruta CM, Zhu M, Charo IF, Weiner HL, Ransohoff RM. Differential roles ... [Published Multiple Sclerosis Research - Jul 23 2014]

Quotes

"In some people autoantibodies will develop, and that's something to deal with and be aware of which we're keenly aware of and dealing with."
"The paper below tackles the thorny issue of whether someone who presents with a tumefactive lesion that turns out on biopsy not to be a tumour, but an inflammatory demyelinating lesion. Another term for these lesions is pseudotumoural; i e. the lesion mimics a tumour. The paper is trying to better define the so called clinico-pathological correlate, or more specifically the radiological-pathological correlate; i e. what features on MRI can be used to predict the underlying pathology? Seven out of 9 of the cases went onto develop MS, i e. they developed new lesions that fulfilled the McDonald diagnostic criteria for dissemination in time and space and no other aetiology could explain the presentation. One case was labelled as having acute hemorrhagic leukoencephalitis (AHLE) and another acute disseminated encephalomyelitis (ADEM). Unfortunately, the MRI findings were not specific enough to identify these latter two cases; hence there is no specific radiological-pathological correlate that can be used to help make a diagnosis. In short, this paper tells us that the MRI findings are non-specific when it comes to MS vs. ADEM/AHLE. The number of cases studied is small and hence the field may benefit from an International effort to pool cases."
"The final frontier may be strategies to access privileged spaces such as the CNS....initial efforts in this regard are likely to depend critically on animal model studies...."
Immanuel Thangaraj, Managing Director and Partner at Essex Woodlands and R-NAV Director, added, "A broad-based approach using radiopharmaceuticals would enable earlier detection and therapeutic intervention before irreversible damage occurs in joints, distinguish between autoimmune and degenerative diseases, and potentially improve patient outcomes and quality of care."

More Content

All (439) | News (386) | Reports (0) | Blogs (52) | Audio/Video (0) | Fact Sheets (1) | Press Releases (0)
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CNS Repair Requires Both Effector and Regulator... [Published Journal of Neuroscience - 22 mins ago]
100 undergraduate students present research [Published University of Kansas - 2 hours ago]
Fat Damages the Lungs of Heavy Drinkers [Published Health Canal - 3 hours ago]
Marker of Tolerance to Infection in Wild Voles:... [Published PLoS Biology - 9 hours ago]
IL-27 controls sepsis-induced impairment of lun... [Published British Journal of the Thorax - 15 hours ago]
Biomineralized Anisotropic Gold Microplate–Mac... [Published ACS Applied Materials & Interfaces - 15 hours ago]
SignaBlok Wins $1.34M NIH Phase II Grant to Adv... [Published Prlog - 20 hours ago]
Ziopharm Joins The CAR Crowd [Published Seeking Alpha - Jul 29 2014]
Clearing up debris to help repair [Published Multiple Sclerosis Research - Jul 29 2014]
Cytokine pathway disruption in a mouse model of... [Published 7thSpace - Jul 29 2014]
MRI of tumefactive lesions [Published Multiple Sclerosis Research - Jul 29 2014]
Translational challenges in targeting latent HI... [Published National AIDS Treatment Advocacy Project - Jul 29 2014]
Macrophages derived from infiltrating monocytes... [Published Journal of Experimental Medicine - Jul 28 2014]
Ever Wondered How Tattoos Stay Permanent? [Video] [Published 2Oceans Vibe News - Jul 28 2014]
A Maternal Gluten-Free Diet Reduces Inflammatio... [Published Diabetes - Jul 27 2014]
Navidea Partners with Essex Woodland's Rheumco ... [Published Pharmacy Choice - Jul 27 2014]
Neutrophils mediate blood brain barrier breakdown [Published Multiple Sclerosis Research - Jul 27 2014]
We can remove HIV from individual cells, resear... [Published Seattle Gay News - Jul 26 2014]
Epidural Decreases Endotoxin-Induced Endothelia... [Published General Medicine eJournal - Jul 25 2014]
The Role of the Circadian Clock in Rheumatoid A... [Published General Medicine eJournal - Jul 25 2014]
Differential responses of osteoblasts and macro... [Published 7thSpace - Jul 25 2014]
Health test for a broad spectrum of health prob... [Published PharmCast - Jul 25 2014]
Targeting residual risk: a new approach to trea... [Published British Journal of Cardiology - Jul 25 2014]
HIV in the Crosshairs: Researchers’ Tool Target... [Published Pharmacy Times - Jul 24 2014]
Peripheral Glia Have a Pivotal Role in the Init... [Published Plosone.org - Jul 24 2014]
Celgene's (CELG) CEO, Robert Hugin on Q2 2014 R... [Published Seeking Alpha - Jul 24 2014]
Scientists Devise Method of Snipping HIV From I... [Published POZ.com - Jul 24 2014]
Scientists 'delete' HIV from human cells [Published Bulawayo24 News - Jul 24 2014]
Biotron's HIV drug candidate reverses impaired ... [Published Bio Spectrum Asia - Jul 24 2014]
Heart Diseases Can Be Healed with Fat: Study Says [Published International Business Times Australia - Jul 24 2014]
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Blogs

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Clearing up debris to help repair [Published Multiple Sclerosis Research - Jul 29 2014]
Rajbhandari L, Tegenge MA, Shrestha S, Ganesh Kumar N, Malik A, Mithal A, Hosmane S, Venkatesan A.  Toll-like receptor 4 deficiency impairs microglial phagocytosis of degenerating axons. Glia. 2014 Jul 8. doi: 10.1002/glia.22719. [Epub ahead of print]Microglia ...
MRI of tumefactive lesions [Published Multiple Sclerosis Research - Jul 29 2014]
Did you present with tumefactive MS? #MSBlog #MSResearch "In recent years I have become interested in the science and philosophy of how we define a disease. This may seem esoteric to you, but it is not and it has many practical implications. For example, ...
Neutrophils mediate blood brain barrier breakdown [Published Multiple Sclerosis Research - Jul 27 2014]
Aubé B, Lévesque SA, Paré A, Chamma E, Kébir H, Gorina R, Lécuyer MA, Alvarez JI, De Koninck Y, Engelhardt B, Prat A, Côté D, Lacroix S. Neutrophils Mediate Blood-Spinal Cord Barrier Disruption in Demyelinating Neuroinflammatory Diseases.  J Immunol. ...
What macrophage does what? [Published Multiple Sclerosis Research - Jul 23 2014]
Yamasaki R, Lu H, Butovsky O, Ohno N, Rietsch AM, Cialic R, Wu PM, Doykan CE, Lin J, Cotleur AC, Kidd G, Zorlu MM, Sun N, Hu W, Liu L, Lee JC, Taylor SE, Uehlein L, Dixon D, Gu J, Floruta CM, Zhu M, Charo IF, Weiner HL, Ransohoff RM. Differential roles ...
Mechanisms Linking Peridontitis and Atheroscler... [Published Fight Aging! - Jul 22 2014]
Chronic infection and inflammation of the gums, peridontitis , is associated with increased risk of atherosclerosis , a clogging of the arteries. This is because inflammation spreads beyond the mouth, and the process of inflammation in artery walls ...
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