Metastasis

Type: Keyphrase
Name: Metastasis
First reported 5 hours ago - Updated 5 hours ago - 1 reports

Scientists In Belgium May Have Just Figured Out How To Stop Cancer From Spreading

Around 90% of deaths from cancer are caused by metastasis - when cancer cells change and move to other parts of the body. This research could mark a sea change in cancer research.Produced by Reuters and Matt JohnstonFollow BI Video ... [Published Business Insider - 5 hours ago]
Entities: Cancer, Belgium, Metastasis
First reported 6 hours ago - Updated 6 hours ago - 1 reports

A DNA aptamer to c-Met inhibits cancer cell migration

Chem. Commun. , 2014, Advance ArticleDOI : 10.1039/C4CC06016D, Communication R. Ueki, S. SandoCLN0003_SL1, an optimized 50-mer DNA aptamer, suppressed the metastasis-related behaviour of cancer cells. This aptamer may be a promising molecular platform ... [Published RSC - 6 hours ago]
Entities: DNA, Metastasis, Tumor
First reported 8 hours ago - Updated 8 hours ago - 2 reports

Belgian Scientists Claim Success in Blocking Tumour Metastasis

It's one of humanity's greatest battles - the fight against cancer. For some it's a death sentence, but new ways of combating tumours are constantly evolving, and scientists at the Université Cathol ... [Published KTVU - 8 hours ago]
Entities: Metastasis, Tumor, Blocking
First reported 12 hours ago - Updated 10 hours ago - 1 reports

Silence Therapeutics interims chart a period of significant progress

’ () interim results statement charts a period in which the group strengthened its financial base, while making significant progress developing its drug candidate and delivery technology.A key milestone was raising £11.4mln, which has allowed the group ... [Published Proactive Investors.co.uk - 12 hours ago]
First reported 11 hours ago - Updated 11 hours ago - 1 reports

Migrastatin analogs and uses thereof

The present invention provides compounds having formula (I): and additionally provides methods for the synthesis thereof, compositions thereof, and methods for the use thereof in the treatment of various disorders including cancer, metastasis and disorders ... [Published Free Patents Online - 11 hours ago]
First reported 18 hours ago - Updated 18 hours ago - 1 reports

Mitogen-activated protein kinase kinase 4 (MAP2K4) promotes human prostate cancer metastasis - Abstract

Prostate cancer (PCa) is the second leading cause of cancer death in the US.Death from PCa primarily results from metastasis. Mitogen-activated protein kinase kinase 4 (MAP2K4) is overexpressed in invasive PCa lesions in humans, and can be inhibited by ... [Published UroToday - 18 hours ago]
First reported Sep 15 2014 - Updated Sep 15 2014 - 1 reports

UK Study Identifies Molecule That Induces Cancer-killing Protein

LEXINGTON, Ky. (Sept. 8, 2014) – A new study by University of Kentucky researchers has identified a novel molecule named Arylquin 1 as a potent inducer of Par-4 secretion from normal cells. Par-4 is a protein that acts as a tumor suppressor, killing cancer ... [Published ScienceNewsline - Sep 15 2014]
First reported Sep 15 2014 - Updated Sep 15 2014 - 1 reports

Novel theory slows cancer growth

Prohibiting the protein ’Ral’ can actively slow the growth of tumours, new research suggests.A group of scientists from the University of Colorado Cancer Center (UCCC) has used computer modelling technology to examine the structure of the Ral protein ... [Published Laboratorytalk - Sep 15 2014]
Entities: Protein, Cancer, Molecule, Tumor
First reported Sep 15 2014 - Updated Sep 15 2014 - 1 reports

Discovery and characterization of small molecules that target the GTPase Ral

The Ras-like GTPases RalA and RalB are important drivers of tumour growth and metastasis. Chemicals that block Ral function would be valuable as research tools and for cancer therapeutics. Here we used protein structure analysis and virtual screening ... [Published BioPortfolio - Sep 15 2014]
First reported Sep 14 2014 - Updated Sep 14 2014 - 1 reports

Mesothelial Cells Promote Ovarian Cancer Metastasis: Study

Ovarian cancer readily spreads to abdominal organs, which are covered by a layer of cells called the mesothelium and less than half of the women diagnosed with ovarian cancer will survive beyond 5 years.Ovarian cancer cells that breach the mesothelium ... [Published MedIndia - Sep 14 2014]
First reported Sep 14 2014 - Updated Sep 14 2014 - 1 reports

New drug blocks gene driving cancer growth

Related Biotechnology, Pharmaceutical and Healthcare NewsWhen active, the protein called Ral can drive tumor growth and metastasis in several human cancers including pancreatic, prostate, lung, colon and bladder. Unfortunately, drugs that block its activity ... [Published BioPortfolio - Sep 14 2014]
First reported Sep 14 2014 - Updated Sep 14 2014 - 2 reports

Nature: New drug blocks gene driving cancer growth

When active, the protein called Ral can drive tumor growth and metastasis in several human cancers including pancreatic, prostate, lung, colon and bladder. Unfortunately, drugs that block its activity are not available. A study published today in the ... [Published Digital Journal - Sep 14 2014]

Quotes

"The primary goal of this phase I clinical trial is to evaluate whether cirmtuzumab is a safe and well-tolerated cancer stem cell-targeted agent in patients with CLL" said Jamieson, chief of the Division of Regenerative Medicine, associate professorprofessor of medicine, director of stem cell research at UC San Diego...
"This work says that if you have a predisposition to getting cancer, wounding might enhance the chance that it will develop" says cell biologist Anthony Oro of Stanford University School of Medicine.”
"Our problem today is not the amount of smart probes or radiotracers," she said. "Our biggest challenge is that we really do not have a sufficient number of oncology imaging people who truly understand what radiation therapy is and how cancer should be imaged."
...Joerg Moeller, Member of the Bayer HealthCare Executive Committee and Head of Global Development. "The initiation of a Phase III clinical trial for ODM-201 marks the starting point for a potential new treatment option for patients whose cancer has not yet spread. This is an important milestone for Bayer in our ongoing effort to meet the unmet needs of men affected by prostate cancer."

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Novel drug targeting leukemia cells enters clin... [Published EurekAlert! - 2 hours ago]
New Appointment to the Scientific Advisory Comm... [Published CW 50 Detroit - 2 hours ago]
Scientists In Belgium May Have Just Figured Out... [Published Business Insider - 5 hours ago]
A DNA aptamer to c-Met inhibits cancer cell mig... [Published RSC - 6 hours ago]
Biomarkers Could Determine Treatment for Esopha... [Published American Journal of Managed Care - 7 hours ago]
Belgian Scientists Claim Success in Blocking Tu... [Published KTVU - 8 hours ago]
Belgian scientists claim success in blocking tu... [Published Yahoo! Maktoob News - 8 hours ago]
Belgian scientists claim success in blocking tu... [Published Reuters Video: Technology - 8 hours ago]
Mammography False Alarms Linked with Later Tumo... [Published Mercola - 10 hours ago]
UPDATE - Silence Therapeutics interims chart a ... [Published Proactiveinvestors United Kingdom RSS feed - 10 hours ago]
ASTRO: Imaging, radiation oncology increasingly... [Published Aunt Minnie - 11 hours ago]
Migrastatin analogs and uses thereof [Published Free Patents Online - 11 hours ago]
Silence Therapeutics interims chart a period of... [Published Proactive Investors.co.uk - 12 hours ago]
Lifestyle and Cancer-Associated DNA Change in t... [Published General Medicine eJournal - 13 hours ago]
Bayer and Orion Initiate Phase III Trial of ODM... [Published Nasdaq - 13 hours ago]
Bayer and Orion Initiate Phase III Trial of ODM... [Published Scottrade - 13 hours ago]
Speech, glorious speech: Yale Edition [Published New Criterion - 14 hours ago]
Breast Cancer With Extensive Peritumoral Vascul... [Published General Medicine eJournal - 14 hours ago]
Tiziana Life Sciences PLC’s Speculative Buy Rat... [Published American Banking News - 18 hours ago]
Mitogen-activated protein kinase kinase 4 (MAP2... [Published UroToday - 18 hours ago]
Epigenetic Drugs: A Hope to Treat Cancer Resist... [Published Health Canal - 20 hours ago]
High-dose radiation plus long-term ADT extended... [Published Orthopedics Today - 23 hours ago]
How Evolutionary Game Theory Is Offering Clues ... [Published The ASCO Post - Sep 15 2014]
Ongoing Clinical Trials Actively Recruiting Pat... [Published The ASCO Post - Sep 15 2014]
Management of the Patient With Postpartum Breas... [Published Cancernetwork.com - Sep 15 2014]
Impaired Osteoblast Differentiation in Annexin ... [Published Plosone.org - Sep 15 2014]
UK Study Identifies Molecule That Induces Cance... [Published ScienceNewsline - Sep 15 2014]
Overexpression of Sirt7 Is Associated With Tumo... [Published The ASCO Post - Sep 15 2014]
Surveillance or metastasis-directed Therapy for... [Published 7thSpace - Sep 15 2014]
Novalis Circle: Expert Clinicians Report on Pro... [Published Scottrade - Sep 15 2014]
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Blogs

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Beaufort Securities Breakfast Today including H... [Published Proactiveinvestors United Kingdom website - Sep 15 2014]
The Markets Market opening: Markets are likely to open lower today. FTSE 100 futures were trading 20.0 points down at 7:00 a.m. New York: Wall Street ended lower on Friday, as ascending retails sales and upbeat consumer sentiment data strengthened ...
[Comment] Small-cell lung cancer: local therapy... [Published The Lancet online - Sep 14 2014]
In The Lancet, Ben Slotman and colleagues report the results of a phase 3 trial of thoracic radiotherapy for small-cell lung cancer. The trial is the most recent in a long line of studies showing that local radiotherapy benefits patients with small-cell ...
Obama and GOP agree to do nothing about ISIS [Published RedState Blog - Sep 09 2014]
More information becomes available about Obama’s strategy for dealing with ISIS. In essence, he wants money . Approving the fund could allow the White House and congressional leaders to escape a tougher vote on authorizing or funding military action ...
Back to the future [Published The Cobden Centre - Sep 05 2014]
“Sir, Arnaud Montebourg, the former French economy minister and the sourest note in the Hollande repertoire, dares to complain of “absurd” austerity policies ? (“Hollande purges cabinet following leftwing revolt”, August 26.) If those policies are absurd, ...
Back To The Future [Published Zero Hedge - Sep 02 2014]
Submitted by Tim Price via Sovereign Man blog , “Sir, Arnaud Montebourg, the former French economy minister and the sourest note in the Hollande repertoire, dares to complain of “absurd” austerity policies ? (“Hollande purges cabinet following leftwing ...
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Audio/Video

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Belgian scientists claim success in blocking tu... [Published Reuters Video: Technology - 8 hours ago]
Rethinking Spring Cleaning [Published Slate Magazine - Apr 25 2014]
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