Murine

Type: Keyphrase
Name: Murine
First reported 2 hours ago - Updated 2 hours ago - 1 reports

Data from Scripps Research Institute Advance Knowledge in Immunoglobulins

(NewsRx) -- By a News Reporter-Staff News Editor at Hematology Week -- Current study results on Immunology have been published. According to news reporting originating in La Jolla, California, by NewsRx journalists, research stated, "Multiple protective ... [Published NewsRX - 2 hours ago]
First reported Apr 24 2014 - Updated Apr 24 2014 - 1 reports

Biokinetics of nanoparticles and susceptibility to particulate exposure in a murine model of cystic ...

Persons with cystic fibrosis (CF) are at-risk for health effects from ambient air pollution but little is known about the interaction of nanoparticles (NP) with CF lungs. Here we study the distribution of inhaled NP in a murine CF model and aim to reveal ... [Published 7thSpace - Apr 24 2014]
Entities: Mutant, Murine, Nanoparticle
First reported Apr 23 2014 - Updated Apr 23 2014 - 1 reports

First patent granted for promising genome-editing technique

Sources: Press release 1 , Press release 2 , Research articleDetails of the CRISPR-Cas9 system and its ability to introduce precise and apparently permanent changes to the genetic code were first published in 2013. Developed from a bacterial system that ... [Published PHG Foundation - Apr 23 2014]
First reported Apr 23 2014 - Updated Apr 23 2014 - 1 reports

Patent Issued for Methods for Increasing the Effectiveness of Antibodies And/Or FCY Receptor-Binding Active Ingredients

By a News Reporter-Staff News Editor at Cancer Gene Therapy Week -- A patent by the inventors Hepper, Martin (Neustadt, DE); Leinenbach, Hans Peter (Tholey, DE); Nocken, Frank ( Frankfurt , DE), filed on September 7, 2007 , was published online on April ... [Published HispanicBusiness.com - Apr 23 2014]
First reported Apr 22 2014 - Updated Apr 22 2014 - 1 reports

Glycogen synthase kinase-3 INHIBITION STIMULATES human CARTILAGE DESTRUCTION and exacerbates murine osteoarthritis

AbstractObjective . To assess the role of glycogen synthase kinase-3 (GSK-3) as a regulator of cartilage destruction in human tissue and a murine model of osteoarthritis (OA).Methods . Surgical destabilisation of the medial meniscus (DMM) was used to ... [Published Arthritis & Rheumatism - Apr 22 2014]
First reported Apr 22 2014 - Updated Apr 22 2014 - 1 reports

Legislature’s bonds package to spur job growth shows political favoritism, prescriptiveness

Maine voters might have six more decisions to make when they visit the polls in November. As the Maine Legislature closed out its lawmaking session Thursday night, legislators gave their support to six borrowing initiatives totaling $50 million.Now, the ... [Published Bangor Daily News - Apr 22 2014]
First reported Apr 22 2014 - Updated Apr 22 2014 - 1 reports

Integrated Preclinical Photosafety Testing Strategy for Systemically Applied Pharmaceuticals

Phototoxic properties of systemically applied pharmaceuticals may be the cause of serious adverse drug reactions. Therefore, a reliable preclinical photosafety assessment strategy, combining in vitro and in vivo approaches in a quantitative manner, is ... [Published Bionity.com - Apr 22 2014]
First reported Apr 18 2014 - Updated Apr 19 2014 - 1 reports

Reports Outline Oligopeptides Study Findings from Karolinska Institute

(NewsRx) -- By a News Reporter-Staff News Editor at Proteomics Weekly -- Investigators publish new report on Peptides. According to news reporting from Stockholm, Sweden, by NewsRx journalists, research stated, "Cigarette smoke induces local inflammation ... [Published NewsRX - Apr 18 2014]
First reported Apr 18 2014 - Updated Apr 18 2014 - 1 reports

Resolving the titer of murine cytomegalovirus by plaque assay using the M2-10B4 cell line and a low ...

Murine cytomegalovirus (MCMV) is increasingly used as an infectious model to investigate host-pathogen interactions in mice. Detailed methods have been published for using primary murine embryonic fibroblasts (MEFs) for preparing stocks and determining ... [Published 7thSpace - Apr 18 2014]
First reported Apr 18 2014 - Updated Apr 18 2014 - 1 reports

Studies from Federal University Yield New Information about Liposomes

(NewsRx) -- By a News Reporter-Staff News Editor at Biotech Business Week -- Researchers detail new data in Biotechnology. According to news reporting out of Belo Horizonte, Brazil, by NewsRx editors, research stated, "This work investigated the use of ... [Published NewsRX - Apr 18 2014]
First reported Apr 18 2014 - Updated Apr 18 2014 - 1 reports

New Stem Cells Study Findings Have Been Reported from S. He et al

(NewsRx) -- By a News Reporter-Staff News Editor at Stem Cell Week -- Investigators publish new report on Stem Cell Research. According to news reporting from Needham, Massachusetts, by NewsRx journalists, research stated, "Hematopoietic stem cell (HSC) ... [Published NewsRX - Apr 18 2014]
First reported Apr 18 2014 - Updated Apr 18 2014 - 1 reports

Recent Findings in Bronchitis Described by Researchers from Huazhong University of Science and Technology

(NewsRx) -- By a News Reporter-Staff News Editor at Blood Weekly -- Investigators publish new report on Bronchial Diseases. According to news originating from Wuhan, People's Republic of China, by NewsRx correspondents, research stated, "Several animal ... [Published NewsRX - Apr 18 2014]

Quotes

"Multiple protective effects of pharmacological activated protein C (APC) are reported in several organ pathologies. To help evaluate the endogenous murine PC system, we characterized a rat monoclonal anti-mouse PC antibody, SPC-54, which inhibited the amidolytic and anticoagulant activities of murine APC by >95%."
...and the behaviors they activate, we can start to follow the circuits into the brain to explore how these behaviors come about," Stowers said. "The implications of these coding schemes go beyond the VNO — we suspect that they are used generally by the mammalian brain." If so, the same truths might hold for mice and men
...cancer-related deaths in the US, representing a significant unmet medical need," said Scott Koenig, M D , Ph D , President and CEO of MacroGenics. "We were able to demonstrate that MGD007 has robust activity against human colorectal cancer in murine xenograft models and a favorable pharmacokinetic profile in non-human primates. We believe that these data support continued investigation of MGD007 as a potential therapeutic option for patients with colorectal cancer and look forward to initiating our first-in-human Phase I study of this product candidate in the second half of this year."
Dr. Vergote commented, "We are very excited to initiate this study with Selinexor in patients with relapsed or refractory carcinomas of the cervix, ovary or uterus. Selinexor has shown intriguing activity in various solid tumor malignancies in the ongoing Phase 1 studies, and we look forward to further evaluating its activity in these difficult-to-treat patients who have limited therapeutic options."

More Content

All (382) | News (359) | Reports (0) | Blogs (18) | Audio/Video (0) | Fact Sheets (3) | Press Releases (2)
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Data from Scripps Research Institute Advance Kn... [Published NewsRX - 2 hours ago]
Alkylglycerols Modulate the Proliferation and D... [Published PLoS medicine - 4 hours ago]
In Trans Complementation of Lethal Factor Revea... [Published PLoS medicine - 7 hours ago]
Unraveling Pheromones: Chemical Signals Can Tri... [Published Medical Daily - 11 hours ago]
Karyopharm conducts drug trials for advanced gy... [Published Examiner.com - 12 hours ago]
MacroGenics announces encouraging preclinical d... [Published Individual.com - 14 hours ago]
Phase 2 Study of Selinexor (KPT-330) Initiated ... [Published Virtual Strategy Magazine - 17 hours ago]
miR-125b induces cellular senescence in maligna... [Published 7thSpace - 17 hours ago]
Food Protection: Researchers from Agricultural ... [Published NewsRX - 18 hours ago]
Seven health benefits of ginseng [Published Natural News - 21 hours ago]
Brd4 Is Essential for IL-1β-Induced Inflammatio... [Published PLoS medicine - 21 hours ago]
Research Results from University of Wisconsin U... [Published HispanicBusiness.com - Apr 24 2014]
Biokinetics of nanoparticles and susceptibility... [Published 7thSpace - Apr 24 2014]
Researchers' Work from University of Science an... [Published HispanicBusiness.com - Apr 24 2014]
Immunogenicity of a Trivalent Human Papillomavi... [Published PLoS medicine - Apr 23 2014]
Selection of Apoptotic Cell Specific Human Anti... [Published PLoS medicine - Apr 23 2014]
Effects of siRNA on RET/PTC3 Junction Oncogene ... [Published PLoS medicine - Apr 23 2014]
Alkyl Caffeates Improve the Antioxidant Activit... [Published PLoS medicine - Apr 23 2014]
First patent granted for promising genome-editi... [Published PHG Foundation - Apr 23 2014]
Posterior Amorphous Corneal Dystrophy Is Associ... [Published PLoS medicine - Apr 23 2014]
T Cell Contamination in Flow Cytometry Gating A... [Published PLoS medicine - Apr 23 2014]
Patent Issued for Methods for Increasing the Ef... [Published HispanicBusiness.com - Apr 23 2014]
Researchers from Uppsala University Describe Fi... [Published HispanicBusiness.com - Apr 23 2014]
Researchers Submit Patent Application, "Method ... [Published 4 Traders - Apr 23 2014]
Human medicines European public assessment repo... [Published European Medicines Agency - Apr 23 2014]
Mitotech S.A. Announces the Initiation of Phase... [Published PRWeb - Apr 23 2014]
Transcriptional Profiling of Mycobacterium tube... [Published PLoS medicine - Apr 23 2014]
Challenges and Opportunities in the Management ... [Published General Medicine eJournal - Apr 23 2014]
Downtrend Call Working As Prestige Brands Holdi... [Published Comtex SmarTrend - Apr 23 2014]
Impact of Metformin on Endothelial Ischemia-Rep... [Published PLoS medicine - Apr 23 2014]
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Blogs

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Re: [tt] [GRG] D-Glucosamine extends life span ... [Published TranshumanTech - Apr 11 2014]
Hail regene1,That's a nice little paper.The full text is at http://dx.doi.org/10.1038/ncomms4563 I like how they got good results with a freelyavailable intervention in long lived mice, andreplicated the results of other studies[1,2,3].The only things ...
Restless Legs Syndrome-associated intronic comm... [Published Genome Research current issue - Apr 01 2014]
Genome-wide association studies (GWAS) identified the MEIS1 locus for Restless Legs Syndrome (RLS), but causal single nucleotide polymorphisms (SNPs) and their functional relevance remain unknown. This locus contains a large number of highly conserved ...
Working With Very Small Embryonic-like Stem Cells [Published Fight Aging! - Apr 01 2014]
The existence of very small embryonic-like cells (VSELs) is debated , as while several groups have claimed to isolate them from adult tissues over the past few years, others have failed to replicate this work. There have been some suggestions that ...
Mouse model of a Virus Infection doesn't get MS [Published Multiple Sclerosis Research - Mar 12 2014]
Reynaud JM, Jégou JF, Welsch J, Horvat B. Human Herpesvirus 6A infection in CD46 transgenic mice: viral persistence in the brain and increased production of proinflammatory chemokines via TLR9. J Virol. 2014 Feb . [Epub ahead of print]Human herpesvirus ...
MURINE FOR EARACHE RELIEF (Chamomila, Mercurius... [Published DailyMed Drug Label Updates for the last seven ... - Mar 05 2014]
Updated Date: Mar 5, 2014 EST ...
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Press Releases

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ZIOPHARM Presents Preclinical Data at AACR Annu... [Published GlobeNewswire: Acquisitions News - Apr 08 2014]
Inflectra™ (infliximab) de la société Hospira r... [Published PR Newswire - Sep 10 2013]
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