Nucleoside

Type: Keyphrase
Name: Nucleoside
First reported 7 hours ago - Updated 7 hours ago - 1 reports

D-stereoselectivity of a human DNA polymerase [Biochemistry]

Rajan Vyas a , 1 , Walter J. Zahurancik a , b , 1 , and Zucai Suo a , b , 2 a Department of Chemistry and Biochemistry and b The Ohio State Biochemistry Program, The Ohio State University, Columbus, OH 43210Edited by Robert Kuchta, University of ... [Published PNAS - 7 hours ago]
First reported 9 hours ago - Updated 9 hours ago - 1 reports

Three new studies help clarify optimal use of combination therapy in chronic hepatitis B patients

: Three new studies presented today at the International Liver CongressTM2014 have helped clarify the optimal use of combination therapy with peginterferon and nucleoside analogues (NUCs) to achieve the best treatment outcomes in patients with chronic ... [Published MyNewsDesk - 9 hours ago]
First reported Jul 10 2014 - Updated Jul 10 2014 - 1 reports

Effects of Tet-Induced Oxidation Products of 5-Methylcytosine on DNA Replication in Mammalian Cells

Recently 5-hydroxymethyl-2′-deoxycytidine (5hmdC), 5-formyl-2′-deoxycytidine (5fdC), and 5-carboxyl-2′-deoxycytidine (5cadC) were discovered in mammalian DNA as oxidation products of 5-methyl-2′-deoxycytidine (5mdC) induced by the ten-eleven translocation ... [Published Chemical Research in Toxicology - Jul 10 2014]
First reported Jul 09 2014 - Updated Jul 09 2014 - 1 reports

BioCryst Pharmaceuticals : Researchers Submit Patent Application, "Methods of Treating Hematologic Cancers", for Approval

By a News Reporter-Staff News Editor at Biotech Week -- From Washington, D.C. , NewsRx journalists report that a patent application by the inventors BANTIA, Shanta ( Birmingham, AL ); BREITFELD, Philip ( Birmingham, AL ); BABU, Yarlagadda S. ( Birmingham, ... [Published 4 Traders - Jul 09 2014]
First reported Jul 09 2014 - Updated Jul 09 2014 - 1 reports

HBsAg seroclearance with NUCs: rare but important

Advanced searchA major breakthrough in the treatment of chronic hepatitis B virus (HBV) infection had been the approval of nucleoside and nucleotide analogues (NUCs), which inhibit the reverse transcriptase and, thereby, dramatically suppress HBV DNA. ... [Published British Journal of the Gut - Jul 09 2014]
First reported Jul 07 2014 - Updated Jul 07 2014 - 1 reports

TAS-102 improved OS in patients with refractory metastatic colorectal cancer

Novel nucleoside anti-tumor agent TAS-102 improved overall survival compared with placebo in patients with metastatic colorectal cancer refractory to standard therapies, according to data presented at the ESMO World Congress on Gastrointestinal Cancer.“Around ... [Published Orthopedics Today - Jul 07 2014]
First reported Jul 04 2014 - Updated Jul 04 2014 - 1 reports

Ribavirin Uptake into Human Hepatocyte HHL5 Cells Is Enhanced by Interferon-α via up-Regulation of the Human Concentrative Nucleoside Transporter (hCNT2)

Ribavirin is a broad spectrum antiviral that increases the response rate in chronic hepatitis C patients when administered in combination with IFNα. Ribavirin is a purine nucleoside derivative, transported into hepatocytes by nucleoside transporters. ... [Published Molecular Pharmaceutics - Jul 04 2014]
First reported Jul 01 2014 - Updated Jul 01 2014 - 1 reports

2′,4′-substituted nucleosides as antiviral agents

Embodiments of the invention are to compounds, methods, and compositions for use in the treatment of viral infections. More specifically embodiments of the invention are 2′,4′-substituted nucleoside compounds useful for the treatment of viral infections, ... [Published Free Patents Online - Jul 01 2014]
First reported Jun 25 2014 - Updated Jun 25 2014 - 1 reports

Nucleoside cyclicphosphates

Cyclic phosphate of nucleoside derivatives for the treatment of viral infections in mammals, which is a compound, its stereoisomers, salts (acid or basic addition salts), hydrates, solvates, or crystalline forms thereof, represented by the following ... [Published Free Patents Online - Jun 25 2014]
Entities: Nucleoside, Phosphate, Acid
First reported Jun 24 2014 - Updated Jun 24 2014 - 1 reports

Solution-Phase Parallel Synthesis of Acyclic Nucleoside Libraries of Purine, Pyrimidine, and Triazole Acetamides

Molecular diversity plays a pivotal role in modern drug discovery against phenotypic or enzyme-based targets using high throughput screening technology. Under the auspices of the Pilot Scale Library Program of the NIH Roadmap Initiative, we produced and ... [Published Journal of Combinatorial Chemistry - Jun 24 2014]
First reported Jun 24 2014 - Updated Jun 24 2014 - 1 reports

Thermostable biocatalyst combination for nucleoside synthesis

A recombinant expression vector comprising: a) the sequence encoding a purine nucleoside phosphorylase (PNPase, E. C. 2.4.2.1), b) the sequence encoding a uridine phosphorylase (UPase, E. C. 2.4.2.3), c) or both; each of the sequences operably linked ... [Published Free Patents Online - Jun 24 2014]
First reported Jun 19 2014 - Updated Jun 20 2014 - 2 reports

TriLink gets patents for new ligation technology in US, Europe and New Zealand

TriLink BioTechnologies (TriLink), a leader in manufacturing high quality oligonucleotides, nucleoside triphosphates and mRNA, has announced that it has been awarded patents in the US (8,728,725), Europe (EP 2451980) and New Zealand (597535) for their ... [Published PBR - News - Jun 20 2014]

Quotes

Mr. Steven Amano, GM and VP of Operations for Emerald Med Farms, added, "With the addition of Thomas, we will have a solid team to assist us in executing our plan to be a major supplier. Emerald Med Farms plans to develop a state-of-the-art facility which will utilize multi-state experience and proven methods to produce the highest of quality medical cannabis. It is our intention to be a leader providing improved products as this industry becomes a major component of the medical industry."
"FIGS. 5A and 5B displays the combination index data for Forodesine/Bendamustine and Forodesine/Fludarabine."

More Content

All (165) | News (149) | Reports (0) | Blogs (11) | Audio/Video (0) | Fact Sheets (1) | Press Releases (4)
sort by: Date | Relevance
D-stereoselectivity of a human DNA polymerase [... [Published PNAS - 7 hours ago]
Three new studies help clarify optimal use of c... [Published MyNewsDesk - 9 hours ago]
Therapy with newer, safer antiretrovirals an op... [Published Aidsmap - 21 hours ago]
Effects of Tet-Induced Oxidation Products of 5... [Published Chemical Research in Toxicology - Jul 10 2014]
QED Connect Inc. Plans to Add World Class Scien... [Published GlobeNewswire: Acquisitions News - Jul 10 2014]
QED Connect Inc. Plans to Add World Class Scien... [Published Town Hall - Jul 10 2014]
BioCryst Pharmaceuticals : Researchers Submit P... [Published 4 Traders - Jul 09 2014]
Patent Application Titled "Thymidine Kinase" Pu... [Published 4 Traders - Jul 09 2014]
HBsAg seroclearance with NUCs: rare but important [Published British Journal of the Gut - Jul 09 2014]
Merck makes big HCV move with Idenix deal [Published Drug Discovery News - Jul 08 2014]
Concept Life Sciences Charts Growth Path with T... [Published Genetic Engineering News - Jul 08 2014]
TAS-102 improved OS in patients with refractory... [Published Orthopedics Today - Jul 07 2014]
Ribavirin Uptake into Human Hepatocyte HHL5 Cel... [Published Molecular Pharmaceutics - Jul 04 2014]
Merck, Gilead Lead Race To Eradicate Hepatitis C [Published Nasdaq - Jul 03 2014]
Pfizer Has It All Wrong, Should Look Into New V... [Published Seeking Alpha - Jul 03 2014]
Patent Issued for Pharmaceutical Compositions C... [Published HispanicBusiness.com - Jul 03 2014]
Idera Pharmaceuticals : Patent Issued for Stabi... [Published 4 Traders - Jul 02 2014]
Researchers at National Institute of Diabetes, ... [Published HispanicBusiness.com - Jul 02 2014]
Vertex Pharmaceuticals : Patent Issued for Thio... [Published 4 Traders - Jul 02 2014]
2′,4′-substituted nucleosides as antiviral agents [Published Free Patents Online - Jul 01 2014]
Method and kit for determination of thymidine k... [Published Free Patents Online - Jul 01 2014]
GlaxoSmithKline joint venture ViiV receives CHM... [Published Zenopa - Jul 01 2014]
TAS-102 Monotherapy Improves OS, PFS in Refract... [Published OncLive - Jun 28 2014]
Improved survival with TAS-102 in mets colorect... [Published Bio-Medicine - Jun 28 2014]
Improved survival with TAS-102 in mets colorect... [Published EurekAlert! - Jun 28 2014]
ESMO GI: Phase III trial shows improved surviva... [Published Ecancer Medicalscience - Jun 28 2014]
EU Panel Gives Nod to Triple Combo Pill for HIV... [Published General Medicine eJournal - Jun 27 2014]
GSK share price: ViiV’s combined HIV treatment ... [Published Invezz - Jun 27 2014]
CHMP Recommends European Approval of Six Drugs [Published Genetic Engineering News - Jun 27 2014]
Triumeq® (dolutegravir/abacavir/lamivudine) sin... [Published PR-Portal.com - Jun 27 2014]
1 2 3 4 5 6
In Focus
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
  •  
Content Volume
Document Volume
Network
Network

Blogs

sort by: Date | Relevance
TriLink gets patents for new ligation technolog... [Published PBR - News - Jun 20 2014]
TriLink BioTechnologies (TriLink), a leader in manufacturing high quality oligonucleotides, nucleoside triphosphates and mRNA, has announced that it has been awarded patents in the US (8,728,725), Europe (EP 2451980) and New Zealand (597535) for their ...
TriLink Awarded Patents for Novel Ligation Tech... [Published Marketwire - Breaking News Releases - Jun 19 2014]
SAN DIEGO, CA--(Marketwired - Jun 19, 2014) - TriLink BioTechnologies ( TriLink ), a leader in manufacturing high quality oligonucleotides, nucleoside triphosphates and mRNA, today announced that it has been awarded patents in the US (8,728,725), Europe ...
TriLink to Open New GMP Facility Aimed at Early... [Published Marketwire - Breaking News Releases - May 21 2014]
SAN DIEGO, CA--(Marketwired - May 21, 2014) -  TriLink BioTechnologies ( TriLink ), a leader in manufacturing high quality oligonucleotides, nucleoside triphosphates and mRNA, today announced their new 2,000 square foot diagnostic and pharmaceutical ...
Expanded DNA alphabet provides more options for... [Published the Foresight Institute - May 15 2014]
Floyd E. Romesberg, associate professor at Scripps Research (Credit: The Scripps Research Institute) Long-time readers of Nanodot may remember the section of Chapter 15 of Nanosystems in which Drexler explores options for producing easier to ...
first living organism that transmits added lett... [Published 3quarksdaily - May 08 2014]
From Scientific American: Scientists at The Scripps Research Institute (TSRI) have engineered a bacterium whose genetic material includes an added pair of DNA "letters," or bases, not found in nature. The cells of this unique bacterium can replicate ...
1 2 3

Press Releases

sort by: Date | Relevance
QED Connect Inc. Plans to Add World Class Scien... [Published GlobeNewswire: Acquisitions News - Jul 10 2014]
Chimerix Regains Worldwide Rights to CMX157 [Published GlobeNewswire: Advertising News - May 16 2014]
Idenix Pharmaceuticals Intends to Appeal Norway... [Published GlobeNewswire: Advertising News - Mar 24 2014]
Idenix Pharmaceuticals Announces Decision by th... [Published GlobeNewswire: Acquisitions News - Jan 29 2014]
1
Contact Us
Sales
Support


Freebase CC-BY Some image thumbnails are sourced from Freebase, licensed under CC-BY

Copyright (C) 2014 Silobreaker Ltd. All rights reserved.
The selection and placement of stories and images on any Silobreaker page are determined automatically by a computer program.
The time or date displayed reflects when an article was added to or updated in Silobreaker.