Oligodendrocyte

Type: Keyphrase
Name: Oligodendrocyte
First reported Jul 22 2014 - Updated Jul 22 2014 - 1 reports

Angiogenesis in Multiple Sclerosis and Experimental Autoimmune Encephalomyelitis

Angiogenesis, the formation of new vessels, is found in Multiple Sclerosis (MS) demyelinating lesions following Vascular Endothelial Growth Factor (VEGF) release and the production of several other angiogenic molecules. The increased energy demand of ... [Published 7thSpace - Jul 22 2014]
First reported Jul 21 2014 - Updated Jul 21 2014 - 1 reports

BioTime receives 14 patents for regenerative medicine and cancer therapy

BioTime, Inc., a biotechnology company, has received 14 new patents in the fields of regenerative medicine and cancer diagnosis and therapy. The patents issued in Australia, Canada, China, Japan, and the US, cover a wide range of core technologies foundational ... [Published Individual.com - Jul 21 2014]
First reported Jul 21 2014 - Updated Jul 21 2014 - 1 reports

Balance of myelination

Lebrun-Julien F, Bachmann L, Norrmén C, Trötzmüller M, Köfeler H, Rüegg MA, Hall MN, Suter U. Balanced mTORC1 Activity in Oligodendrocytes Is Required for Accurate CNS Myelination. J Neurosci. 2014; 34(25):8432-48. doi: 10.1523/JNEUROSCI.1105-14.2014.The ... [Published Multiple Sclerosis Research - Jul 21 2014]
First reported Jul 16 2014 - Updated Jul 16 2014 - 1 reports

Progressive Disorganization of Paranodal Junctions and Compact Myelin Due to Loss of DCC Expression by Oligodendrocytes

1 , * , Jenea M. Bin 1 , * , Eric Beaumont 3 , Alexandre Boutet 2 , Paul Krimpenfort 4 , Abbas F. Sadikot 2 , and Timothy E. Kennedy 1 1 Department of Neurology and Neurosurgery and 2 Cone Laboratory, Montréal Neurological Institute, McGill University, ... [Published Journal of Neuroscience - Jul 16 2014]
First reported Jul 15 2014 - Updated Jul 15 2014 - 1 reports

BIOTIME : Announces Issuance of 14 Patents in the Fields of Regenerative Medicine, and Cancer Diagnosis and Therapy

"As a biotechnology company, our intellectual property portfolio is an important asset that supports our product development programs and drives value in our business transactions," said Dr. Michael D. West , Ph.D., BioTime's Chief Executive Officer. ... [Published 4 Traders - Jul 15 2014]
First reported Jul 09 2014 - Updated Jul 09 2014 - 1 reports

Researchers from Aichi Institute of Technology Detail Findings in Genetics and Autoimmune Diseases (Activation of the STING Adaptor Attenuates...

Researchers from Aichi Institute of Technology Detail Findings in Genetics and Autoimmune Diseases (Activation of the STING Adaptor Attenuates Experimental Autoimmune Encephalitis)By a News Reporter-Staff News Editor at Biotech Week -- Current study results ... [Published 4 Traders - Jul 09 2014]
First reported Jul 08 2014 - Updated Jul 08 2014 - 1 reports

A quick screen to find a myelination drug.

Mei F, Fancy SP, Shen YA, Niu J, Zhao C, Presley B, Miao E, Lee S, Mayoral SR, Redmond SA, Etxeberria A, Xiao L, Franklin RJ, Green A, Hauser SL, Chan JR Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis. ... [Published Multiple Sclerosis Research - Jul 08 2014]
First reported Jul 04 2014 - Updated Jul 04 2014 - 1 reports

NEWS FROM THE AAN ANNUAL MEETING: RXR Agonist Shows Potential for Myelin Repair In Vitro, New Study Suggests

Collins, Thomas R.Back to Top | Article Outline ARTICLE IN BRIEF FigureImage ToolsIRX4204, a retinoid X receptor-agonist studied for prostate cancer, also promotes differentiation of oligodendrocytes and the formation of regulatory T cells and inhibits ... [Published Neurology Today - Jul 04 2014]
First reported Jul 02 2014 - Updated Jul 02 2014 - 1 reports

Key Player in Myelination ID’d, May Hold Promise for MS Treatment: Study

Researchers at the University at Buffalo (UB) have reportedly pinpointed SOX10 as a key player that initiates the critical myelination process in the brain, paving the way toward the ultimate goal of treating multiple sclerosis (MS) by transplanting the ... [Published Rehab Manegement - Jul 02 2014]
First reported Jun 30 2014 - Updated Jul 01 2014 - 3 reports

Progress Towards Inducing Greater Remyelination

Nerves are sheathed in myelin . That sheathing deteriorates to some degree with age, and more dramatically in demyelinating conditions such as multiple sclerosis (MS) . Some of the approaches taken by researchers working on conditions such as MS ... [Published Fight Aging! - Jul 01 2014]
First reported Jun 24 2014 - Updated Jun 24 2014 - 1 reports

Roche partners up in effort to discover new multiple sclerosis treatments

BASEL, Switzerland—Roche announced June 23 that it has entered into an exclusive partnership with and Versant Ventures to create Inception 5, a new company dedicated to the research and development of novel small-molecule remyelinating therapies for patients ... [Published Drug Discovery News - Jun 24 2014]
First reported Jun 24 2014 - Updated Jun 24 2014 - 1 reports

Interaction of myelin basic protein with cytoskeletal and signaling proteins in cultured primary ...

The classic myelin basic protein (MBP) isoforms are intrinsically-disordered proteins of 14-21.5 kDa in size arising from the Golli (Gene in the Oligodendrocyte Lineage) gene complex, and are responsible for formation of the multilayered myelin sheath ... [Published 7thSpace - Jun 24 2014]
Entities: Protein, myelin, Interaction

Quotes

...The claims cover certain PureStem cell types as well as certain products made from them used in patients. Titled "Methods and Compositions for In Vitro and In Vivo Chondrogenesis" this patent is one of numerous patents useful to BioTime's subsidiary OrthoCyte Corporation
...to normalize altered endocannabinoid levels during pregnancy to ensure correct embryonic brain development", says the MedUni Vienna researcher. "We have demonstrated that the body's own cannabinoids are able to regulate an important signalling system in the development of embryonic brain circuitry."
According to the news reporters, the research concluded: "These findings reveal dichotomous roles for the STING/IFN-alpha beta pathway in either stimulating or suppressing autoimmunity and identify STING-activating reagents as a novel class of immune modulatory drugs."
..."We try to find ways to classify brain tumors according to the known pathogenesis processes," Fan explained. "This could help with diagnoses and maybe could avoid unnecessary treatment."

More Content

All (64) | News (28) | Reports (0) | Blogs (35) | Audio/Video (0) | Fact Sheets (1) | Press Releases (0)
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Angiogenesis in Multiple Sclerosis and Experime... [Published 7thSpace - Jul 22 2014]
Increased levels of the body’s own cannabinoids... [Published Health Canal - Jul 21 2014]
BioTime receives 14 patents for regenerative me... [Published Individual.com - Jul 21 2014]
Balance of myelination [Published Multiple Sclerosis Research - Jul 21 2014]
Increased levels of the body's own cannabinoids... [Published Medical Xpress - Jul 17 2014]
Progressive Disorganization of Paranodal Juncti... [Published Journal of Neuroscience - Jul 16 2014]
Animals move less when they have problems [Published Multiple Sclerosis Research - Jul 16 2014]
BIOTIME : Announces Issuance of 14 Patents in t... [Published 4 Traders - Jul 15 2014]
BioTime Announces Issuance of 14 Patents in the... [Published Myrtle Beach Sun News - Jul 14 2014]
LifeMap Sciences, a Subsidiary of BioTime, Anno... [Published Business Wire - Jul 11 2014]
Researchers from Aichi Institute of Technology ... [Published 4 Traders - Jul 09 2014]
A quick screen to find a myelination drug. [Published Multiple Sclerosis Research - Jul 08 2014]
Statistical Analysis Could Improve Understandin... [Published Scientific Computing - Jul 08 2014]
Methods for diagnosing CNS disorders with fusio... [Published PharmCast - Jul 04 2014]
NEWS FROM THE AAN ANNUAL MEETING: RXR Agonist S... [Published Neurology Today - Jul 04 2014]
Key Player in Myelination ID’d, May Hold Promis... [Published Rehab Manegement - Jul 02 2014]
Progress Towards Inducing Greater Remyelination [Published Fight Aging! - Jul 01 2014]
Transcriptional regulation of human OPC fate [N... [Published PNAS - Jul 01 2014]
'Master switch' for myelination in human brain ... [Published Medical Xpress - Jun 30 2014]
BioTime Subsidiary Asterias Biotherapeutics Ann... [Published HispanicBusiness.com - Jun 26 2014]
Roche partners up in effort to discover new mul... [Published Drug Discovery News - Jun 24 2014]
Interaction of myelin basic protein with cytosk... [Published 7thSpace - Jun 24 2014]
Tapping UCSF Invention, Roche and Versant Dive ... [Published Xconomy - Jun 23 2014]
A molecule that blocks remyelination [Published Multiple Sclerosis Research - Jun 22 2014]
Balanced mTORC1 Activity in Oligodendrocytes Is... [Published Journal of Neuroscience - Jun 20 2014]
An Amino Terminal Phosphorylation Motif Regulat... [Published Journal of Neuroscience - Jun 20 2014]
Young blood for old animals helps your memory [Published Multiple Sclerosis Research - Jun 18 2014]
Higher-salt saline solution reduces bronchiolit... [Published San Francisco Chronicle - Jun 18 2014]
Specific ablation of Nampt in adult neural stem... [Published EMBO Journal - Jun 17 2014]
BioTime Subsidiary Asterias Biotherapeutics Rai... [Published Nasdaq - Jun 17 2014]
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sort by: Date | Relevance
Balance of myelination [Published Multiple Sclerosis Research - Jul 21 2014]
Lebrun-Julien F, Bachmann L, Norrmén C, Trötzmüller M, Köfeler H, Rüegg MA, Hall MN, Suter U. Balanced mTORC1 Activity in Oligodendrocytes Is Required for Accurate CNS Myelination. J Neurosci. 2014; 34(25):8432-48. doi: 10.1523/JNEUROSCI.1105-14.2014.The ...
Animals move less when they have problems [Published Multiple Sclerosis Research - Jul 16 2014]
Takemiya T, Takeuchi C. Traveled distance is a sensitive and accurate marker of motor dysfunction in a mouse model ofmultiple sclerosis. ISRN Neurosci. 2013;2013:170316.Multiple sclerosis (MS) is a common central nervous system disease associated with ...
A quick screen to find a myelination drug. [Published Multiple Sclerosis Research - Jul 08 2014]
Mei F, Fancy SP, Shen YA, Niu J, Zhao C, Presley B, Miao E, Lee S, Mayoral SR, Redmond SA, Etxeberria A, Xiao L, Franklin RJ, Green A, Hauser SL, Chan JR Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis. ...
Progress Towards Inducing Greater Remyelination [Published Fight Aging! - Jul 01 2014]
Nerves are sheathed in myelin . That sheathing deteriorates to some degree with age, and more dramatically in demyelinating conditions such as multiple sclerosis (MS) . Some of the approaches taken by researchers working on conditions such as MS ...
A molecule that blocks remyelination [Published Multiple Sclerosis Research - Jun 22 2014]
Tepavčević V, Kerninon C, Aigrot MS, Meppiel E, Mozafari S, Arnould-Laurent R, Ravassard P, Kennedy TE, Nait-Oumesmar B, Lubetzki C. Early netrin-1 expression impairs central nervous system remyelination.  Ann Neurol. 2014 Jun. doi: 10.1002/ana.24201. ...
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