Oligodendrocyte

Type: Keyphrase
Name: Oligodendrocyte
First reported 17 hours ago - Updated 17 hours ago - 1 reports

Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases

IntroductionDifferent neurodegenerative diseases share similar dysfunctional phenotypes, such as misfolded protein aggregates, neuronal cell death, inflammation, and cognitive decline. Yet, the complexity of these diseases has hindered efforts to obtain ... [Published Molecular Systems Biology - 17 hours ago]
First reported Jul 28 2014 - Updated Jul 28 2014 - 1 reports

Study May Help Pave Way to Cell Therapy for MS Patients, Researchers Say

Scientists at the New York Stem Cell Foundation (NYSCF) Research Institute reportedly generated induced pluripotent stem (iPS) cells lines from skin samples of patients with primary progressive multiple sclerosis (MS) and developed a protocol to induce ... [Published Rehab Manegement - Jul 28 2014]
First reported Jul 27 2014 - Updated Jul 28 2014 - 2 reports

Cure for MS moves closer

We’re closer than ever to seeing a cure for MS ,thanks to scientists from the New York Stem Cell Foundation (NYSCF) Research Institute.Using skin samples from people with the disease, they’ve grown new stem cells and for the first time  successfully encouraged ... [Published Shiny Shiny - Jul 28 2014]
First reported Jul 24 2014 - Updated Jul 24 2014 - 3 reports

Cell therapy for multiple sclerosis patients: Closer than ever?

For the first time, scientists generated induced pluripotent stem cells lines from skin samples of patients with primary progressive multiple sclerosis and further, they developed an accelerated protocol to induce these stem cells into becoming oligodendrocytes, ... [Published MS News - Jul 24 2014]
First reported Jul 24 2014 - Updated Jul 24 2014 - 1 reports

Asterias Biotherapeutics Announces Live Investor Webcast

MENLO PARK, Calif.About Asterias BiotherapeuticsAsterias' core technologies center on stem cells capable of becoming all of the cell types in the human body, a property called pluripotency. Asterias plans to develop therapies based on pluripotent stem ... [Published Bio-Medicine - Jul 24 2014]
First reported Jul 21 2014 - Updated Jul 21 2014 - 1 reports

BioTime receives 14 patents for regenerative medicine and cancer therapy

BioTime, Inc., a biotechnology company, has received 14 new patents in the fields of regenerative medicine and cancer diagnosis and therapy. The patents issued in Australia, Canada, China, Japan, and the US, cover a wide range of core technologies foundational ... [Published Individual.com - Jul 21 2014]
First reported Jul 21 2014 - Updated Jul 21 2014 - 1 reports

Balance of myelination

Lebrun-Julien F, Bachmann L, Norrmén C, Trötzmüller M, Köfeler H, Rüegg MA, Hall MN, Suter U. Balanced mTORC1 Activity in Oligodendrocytes Is Required for Accurate CNS Myelination. J Neurosci. 2014; 34(25):8432-48. doi: 10.1523/JNEUROSCI.1105-14.2014.The ... [Published Multiple Sclerosis Research - Jul 21 2014]
First reported Jul 16 2014 - Updated Jul 16 2014 - 1 reports

Progressive Disorganization of Paranodal Junctions and Compact Myelin Due to Loss of DCC Expression by Oligodendrocytes

1 , * , Jenea M. Bin 1 , * , Eric Beaumont 3 , Alexandre Boutet 2 , Paul Krimpenfort 4 , Abbas F. Sadikot 2 , and Timothy E. Kennedy 1 1 Department of Neurology and Neurosurgery and 2 Cone Laboratory, Montréal Neurological Institute, McGill University, ... [Published Journal of Neuroscience - Jul 16 2014]
First reported Jul 08 2014 - Updated Jul 08 2014 - 1 reports

A quick screen to find a myelination drug.

Mei F, Fancy SP, Shen YA, Niu J, Zhao C, Presley B, Miao E, Lee S, Mayoral SR, Redmond SA, Etxeberria A, Xiao L, Franklin RJ, Green A, Hauser SL, Chan JR Micropillar arrays as a high-throughput screening platform for therapeutics in multiple sclerosis. ... [Published Multiple Sclerosis Research - Jul 08 2014]
First reported Jul 04 2014 - Updated Jul 04 2014 - 1 reports

NEWS FROM THE AAN ANNUAL MEETING: RXR Agonist Shows Potential for Myelin Repair In Vitro, New Study Suggests

Collins, Thomas R.Back to Top | Article Outline ARTICLE IN BRIEF FigureImage ToolsIRX4204, a retinoid X receptor-agonist studied for prostate cancer, also promotes differentiation of oligodendrocytes and the formation of regulatory T cells and inhibits ... [Published Neurology Today - Jul 04 2014]
First reported Jul 02 2014 - Updated Jul 02 2014 - 1 reports

Key Player in Myelination ID’d, May Hold Promise for MS Treatment: Study

Researchers at the University at Buffalo (UB) have reportedly pinpointed SOX10 as a key player that initiates the critical myelination process in the brain, paving the way toward the ultimate goal of treating multiple sclerosis (MS) by transplanting the ... [Published Rehab Manegement - Jul 02 2014]
First reported Jul 01 2014 - Updated Jul 01 2014 - 2 reports

Progress Towards Inducing Greater Remyelination

Nerves are sheathed in myelin . That sheathing deteriorates to some degree with age, and more dramatically in demyelinating conditions such as multiple sclerosis (MS) . Some of the approaches taken by researchers working on conditions such as MS ... [Published Fight Aging! - Jul 01 2014]

Quotes

"In some embodiments, the immunogenic composition further comprises an immunostimulatory substance. In some embodiments, the immunostimulatory substance is a Toll-like receptor (TLR) inducer. In certain embodiments the TLR inducer is selected from the group consisting of: a CpG-containing oligonucleotide, an immunostimulatory nucleic acid, a lipopolysaccharide, a peptidoglycan, a lipoteichoic acid, an imidazoquinoline compound, a flagellin, a lipoprotein, and an immunostimulatory organic molecule. In a currently preferred embodiment, the TLR inducer is a CpG-containing oligonucleotide. In some embodiments, the immunogenic composition is administered together with an adjuvant."

More Content

All (69) | News (31) | Reports (0) | Blogs (37) | Audio/Video (0) | Fact Sheets (1) | Press Releases (0)
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Mice work may send you down the wrong path becu... [Published Multiple Sclerosis Research - 5 hours ago]
"Anti-Measles Cancer Immunotherapy" in Patent A... [Published HispanicBusiness.com - 6 hours ago]
Common dysregulation network in the human prefr... [Published Molecular Systems Biology - 17 hours ago]
Stem Cell Therapy Breakthrough for MS [Published EMax Health - Jul 29 2014]
lentiviral anti-lingo supports remyelination [Published Multiple Sclerosis Research - Jul 29 2014]
Study May Help Pave Way to Cell Therapy for MS ... [Published Rehab Manegement - Jul 28 2014]
Cure for MS moves closer [Published Shiny Shiny - Jul 28 2014]
Closer than ever? -- ScienceDaily [Published DailyMe.Com - Jul 27 2014]
Cell therapy for multiple sclerosis patients: C... [Published MS News - Jul 24 2014]
Scientists 1 step closer to cell therapy for mu... [Published Medical Xpress - Jul 24 2014]
NYSCF scientists 1 step closer to cell therapy ... [Published EurekAlert! - Jul 24 2014]
Asterias Biotherapeutics Announces Live Investo... [Published Bio-Medicine - Jul 24 2014]
Asterias Biotherapeutics Announces Live Investo... [Published Wall Street Business Network - Jul 24 2014]
Angiogenesis in Multiple Sclerosis and Experime... [Published 7thSpace - Jul 22 2014]
Increased levels of the body’s own cannabinoids... [Published Health Canal - Jul 21 2014]
BioTime receives 14 patents for regenerative me... [Published Individual.com - Jul 21 2014]
Balance of myelination [Published Multiple Sclerosis Research - Jul 21 2014]
Increased levels of the body's own cannabinoids... [Published Medical Xpress - Jul 17 2014]
Progressive Disorganization of Paranodal Juncti... [Published Journal of Neuroscience - Jul 16 2014]
Animals move less when they have problems [Published Multiple Sclerosis Research - Jul 16 2014]
BIOTIME : Announces Issuance of 14 Patents in t... [Published 4 Traders - Jul 15 2014]
BioTime Announces Issuance of 14 Patents in the... [Published Myrtle Beach Sun News - Jul 14 2014]
LifeMap Sciences, a Subsidiary of BioTime, Anno... [Published Business Wire - Jul 11 2014]
Researchers from Aichi Institute of Technology ... [Published 4 Traders - Jul 09 2014]
A quick screen to find a myelination drug. [Published Multiple Sclerosis Research - Jul 08 2014]
Statistical Analysis Could Improve Understandin... [Published Scientific Computing - Jul 08 2014]
Methods for diagnosing CNS disorders with fusio... [Published PharmCast - Jul 04 2014]
NEWS FROM THE AAN ANNUAL MEETING: RXR Agonist S... [Published Neurology Today - Jul 04 2014]
Key Player in Myelination ID’d, May Hold Promis... [Published Rehab Manegement - Jul 02 2014]
Progress Towards Inducing Greater Remyelination [Published Fight Aging! - Jul 01 2014]
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Blogs

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Mice work may send you down the wrong path becu... [Published Multiple Sclerosis Research - 5 hours ago]
Kraev A. Parallel universes of Black Six biology. Biol Direct. 2014 Jul 19;9(1):18Creation of lethal and synthetic lethal mutations in an experimental organism is a cornerstone of genetic dissection of gene function, and is related to the concept of ...
lentiviral anti-lingo supports remyelination [Published Multiple Sclerosis Research - Jul 29 2014]
Wang CJ, Qu CQ, Zhang J, Fu PC, Guo SG, Tang RH.  Lingo-1 Inhibited by RNA Interference Promotes Functional Recovery of Experimental Autoimmune Encephalomyelitis.  Anat Rec (Hoboken). 2014 Jul . doi: 10.1002/ar.22988. [Epub ahead of print]Lingo-1 is a ...
Cell therapy for multiple sclerosis patients: C... [Published MS News - Jul 24 2014]
For the first time, scientists generated induced pluripotent stem cells lines from skin samples of patients with primary progressive multiple sclerosis and further, they developed an accelerated protocol to induce these stem cells into becoming oligodendrocytes, ...
Balance of myelination [Published Multiple Sclerosis Research - Jul 21 2014]
Lebrun-Julien F, Bachmann L, Norrmén C, Trötzmüller M, Köfeler H, Rüegg MA, Hall MN, Suter U. Balanced mTORC1 Activity in Oligodendrocytes Is Required for Accurate CNS Myelination. J Neurosci. 2014; 34(25):8432-48. doi: 10.1523/JNEUROSCI.1105-14.2014.The ...
Animals move less when they have problems [Published Multiple Sclerosis Research - Jul 16 2014]
Takemiya T, Takeuchi C. Traveled distance is a sensitive and accurate marker of motor dysfunction in a mouse model ofmultiple sclerosis. ISRN Neurosci. 2013;2013:170316.Multiple sclerosis (MS) is a common central nervous system disease associated with ...
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