Oligodendrocyte

Type: Keyphrase
Name: Oligodendrocyte
First reported 13 hours ago - Updated 13 hours ago - 1 reports

White matter might matter much more than we thought

Computer-generated image of three cortical neurons showing differences in the distribution of myelin (shown in white). Photograph: Daniel Berger and Giulio Tomassy/Harvard University. Look up ‘myelin’ in any neuroscience textbook and you’ll find something ... [Published Guardian.co.uk - 13 hours ago]
First reported Apr 16 2014 - Updated Apr 16 2014 - 1 reports

Myocilin Is Involved in NgR1/Lingo-1-Mediated Oligodendrocyte Differentiation and Myelination of the Optic Nerve

1 , Naoki Nakaya 1 , Mones Abu-Asab 2 , Hong Sug Kim 3 , and Stanislav I. Tomarev 1 1 Retinal Ganglion Cell Biology Section, Laboratory of Retinal Cell and Molecular Biology and 2 Histology Core, National Eye Institute, National Institutes of Health ... [Published Journal of Neuroscience - Apr 16 2014]
First reported Apr 11 2014 - Updated Apr 11 2014 - 1 reports

The Olig family affects central nervous system development and disease

PUBLIC RELEASE DATE: 11-Apr-2014The oligodendrocyte transcription family (Olig family) is widely expressed in the central nervous system of various mammals, and plays a critical role in central nervous system development by controlling differentiation ... [Published EurekAlert! - Apr 11 2014]
First reported Apr 10 2014 - Updated Apr 10 2014 - 1 reports

Brain activity drives dynamic changes in neural fiber insulation

Transmission electron micrograph image illustrating a myelinated axon in an optogeneticallystimulated mouse brain. Credit: David PurgerThe brain is a wonderfully flexible and adaptive learning tool. For decades, researchers have known that this flexibility, ... [Published Medical Xpress - Apr 10 2014]
First reported Apr 10 2014 - Updated Apr 10 2014 - 1 reports

Comprehensive genomic analysis sorts low-grade brain tumors sorts into three categories

Comprehensive genomic analysis of low-grade brain tumors sorts them into three categories, one of which has the molecular hallmarks and shortened survival of glioblastoma multiforme, the most lethal of brain tumors, researchers reported at the American ... [Published News-Medical.Net - Apr 10 2014]
Entities: Tumor, Genome, astrocytoma
First reported Apr 08 2014 - Updated Apr 08 2014 - 1 reports

Genomic Analysis Leads To More Accurate Classification Of Brain Tumors

Comprehensive genomic analysis of low-grade brain tumors using data from The Cancer Genome Atlas (TCGA) brain tumor studies sorts them into three categories, one of which has the molecular hallmarks and shortened survival of glioblastoma multiforme, ... [Published Scientific Blogging - Medicine - Apr 08 2014]
First reported Apr 08 2014 - Updated Apr 08 2014 - 1 reports

Deep, integrated genomic analysis re-classifies lower-grade brain tumors

PUBLIC RELEASE DATE: 8-Apr-2014Comprehensive genomic analysis of low-grade brain tumors sorts them into three categories, one of which has the molecular hallmarks and shortened survival of glioblastoma multiforme, the most lethal of brain tumors, researchers ... [Published EurekAlert! - Apr 08 2014]
First reported Apr 03 2014 - Updated Apr 03 2014 - 1 reports

Researchers at University of Manitoba Report New Data on Peroxidases

By a News Reporter-Staff News Editor at Psychology & Psychiatry Journal -- Investigators discuss new findings in Enzymes and Coenzymes. According to news originating from Winnipeg, Canada, by VerticalNews correspondents, research stated, "Cuprizone (CPZ) ... [Published HighBeam Research - Apr 03 2014]
First reported Mar 31 2014 - Updated Mar 31 2014 - 1 reports

Role of type-2 astrocytes on the repair of spinal cord injury

PUBLIC RELEASE DATE: 29-Mar-2014Increasing expression of bone morphogenetic proteins at the lesion site of the central nervous system possibly induces oligodendrocyte precursor cells to differentiate into type-2 astrocytes. While the restriction of oligodendrocyte ... [Published EurekAlert! - Mar 31 2014]
First reported Mar 27 2014 - Updated Mar 27 2014 - 1 reports

Patent Issued for Pure Populations of Astrocyte Restricted Precursor Cells and Methods for Isolation and Use

By a News Reporter-Staff News Editor at Stem Cell Week -- A patent by the inventors Rao, Mahendra S. ( Timonium, MD ); Mujtaba, Tahmina ( Blaine, MN ); Wu, Yuan Yuan ( Salt Lake City, UT ); Liu, Ying ( Baltimore, MD ), filed on April 30, 2009 , was published ... [Published 4 Traders - Mar 27 2014]
First reported Mar 26 2014 - Updated Mar 26 2014 - 2 reports

Conditional Ablation of Raptor or Rictor Has Differential Impact on Oligodendrocyte Differentiation and CNS Myelination

1 , JinXiang Dai 1 , Hilary H. Sachs 1 , Jared T. Ahrendsen 1 , Teresa L. Wood 2 , and Wendy B. Macklin 1 1 Department of Cell and Developmental Biology, University of Colorado School of Medicine, Aurora, Colorado 80045, and 2 Department of Neurology ... [Published Journal of Neuroscience - Mar 26 2014]
First reported Mar 20 2014 - Updated Mar 20 2014 - 1 reports

Id2 Mediates Oligodendrocyte Precursor Cell Maturation Arrest and Is Tumorigenic in a PDGF-Rich Microenvironment

Maturation defects occurring in adult tissue progenitor cells have the potential to contribute to tumor development; however, there is little experimental evidence implicating this cellular mechanism in the pathogenesis of solid tumors. Inhibitor of DNA-binding ... [Published Bionity.com - Mar 20 2014]

Quotes

It’s still not clear exactly what all this means, but Tomassy and his colleagues conclude that it may have "served the evolutionary expansion and diversification of the neocortex by enabling the generation of different arrays of communication mechanisms and the emergence of highly complex neuronal behaviors." In other words, myelin is likely to play an important role in synaptic plasticity, one of the mechanisms by which brain circuits are modified in response...
"Pathogenetic treatment of MS includes the use of a number of drugs, such as interferon beta (IFN.sub..beta.)-1a and IFN.sub..beta.-1b. The therapeutic effects of IFN.sub..beta. are associated with the inhibition of antigen presentation and suppression of both the proliferation and the activation of inflammatory cells. IFN-.beta.1 induces anti-inflammatory cytokines and a change in the cytokine profile toward the anti-inflammatory phenotype, and also reduces entry of leukocytes into the central nervous system through the blood-brain barrier (see, e g., Chofflon (2005) Biodrugs 19:299-308; Schreiner et al. (2004) J Neuroimmunol. 155:172-182; Leppert et al. (1996) Ann Neurol. 40:846-852; Finocchiaro et al. (2002) J Interferon Cytokine Res. 22:1181-1184; Huynh et al. (1995) J Neuroimmunol. 60:63-73; Liu et al. (2001) J Neuroimmunol. 112:153-162."

More Content

All (85) | News (37) | Reports (0) | Blogs (47) | Audio/Video (0) | Fact Sheets (1) | Press Releases (0)
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White matter might matter much more than we tho... [Published Guardian.co.uk - 13 hours ago]
Evolutionary and Developmental Contributions fo... [Published Sexual Development - Apr 24 2014]
Patent Issued for Treatment Method for Relapsin... [Published HispanicBusiness.com - Apr 23 2014]
SYSTEM RESEARCH : New Neuroscience Study Result... [Published 4 Traders - Apr 23 2014]
Study finds long-term survival of human neural ... [Published EurekAlert! - Apr 23 2014]
Prevalence and Clinicopathologic Characteristic... [Published PLoS medicine - Apr 22 2014]
Opexa Therapeutics to Attend the American Acade... [Published Nasdaq - Apr 22 2014]
Specific Binding and Characteristics of 18β-Gly... [Published PLoS medicine - Apr 22 2014]
Know the brain, and its axons, by the clothes t... [Published Medical Xpress - Apr 18 2014]
A Statin Is Found to Ameliorate Late-Stage Disa... [Published Neurology Today - Apr 18 2014]
Myocilin Is Involved in NgR1/Lingo-1-Mediated O... [Published Journal of Neuroscience - Apr 16 2014]
Brain nerve cells found to aid nerve growth [Published San Francisco Chronicle - Apr 16 2014]
Does EBV have nothing to do with MS? [Published Multiple Sclerosis Research - Apr 15 2014]
The Ying and Yang of Science relating to macrop... [Published Multiple Sclerosis Research - Apr 12 2014]
The Olig family affects central nervous system ... [Published EurekAlert! - Apr 11 2014]
Brain activity drives dynamic changes in neural... [Published Medical Xpress - Apr 10 2014]
Comprehensive genomic analysis sorts low-grade ... [Published News-Medical.Net - Apr 10 2014]
Patent Issued for Neural Scaffolds [Published HispanicBusiness.com - Apr 10 2014]
Genomic Analysis Leads To More Accurate Classif... [Published Scientific Blogging - Medicine - Apr 08 2014]
Deep, integrated genomic analysis re-classifies... [Published EurekAlert! - Apr 08 2014]
Not all attacks are created equal [Published Multiple Sclerosis Research - Apr 04 2014]
Researchers at University of Manitoba Report Ne... [Published HighBeam Research - Apr 03 2014]
Tempo Bioscience Launches Human Cellular And Bi... [Published Drug Discovery Online - Apr 02 2014]
PML: are stem cells and B cells a trojan horse? [Published Multiple Sclerosis Research - Apr 01 2014]
Role of type-2 astrocytes on the repair of spin... [Published EurekAlert! - Mar 31 2014]
Study identifies key player in motor neuron dea... [Published Brightsurf Science News - Mar 28 2014]
Patent Issued for Pure Populations of Astrocyte... [Published 4 Traders - Mar 27 2014]
Study identifies key player in motor neuron dea... [Published EurekAlert! - Mar 26 2014]
Conditional Ablation of Raptor or Rictor Has Di... [Published Journal of Neuroscience - Mar 26 2014]
Mammalian Target of Rapamycin Promotes Oligoden... [Published Journal of Neuroscience - Mar 26 2014]
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Does EBV have nothing to do with MS? [Published Multiple Sclerosis Research - Apr 15 2014]
What is the difference between a belief and a hypothesis? #MSBlog #MSResearch Does EBV cause MS? Join the debate. #MSBlog #MSResearch "The study below found no differences in EBV viral loads in the spinal fluid and peripheral between MSers and controls. ...
The Ying and Yang of Science relating to macrop... [Published Multiple Sclerosis Research - Apr 12 2014]
Ridderstad Wollberg A, Ericsson-Dahlstrand A, Juréus A, Ekerot P, Simon S, Nilsson M, Wiklund SJ, Berg AL, Ferm M, Sunnemark D, Johansson R.  Pharmacological inhibition of the chemokine receptor CX3CR1 attenuates disease in a chronic-relapsing rat model ...
Genomic Analysis Leads To More Accurate Classif... [Published Scientific Blogging - Medicine - Apr 08 2014]
Comprehensive genomic analysis of low-grade brain tumors using data from The Cancer Genome Atlas (TCGA) brain tumor studies sorts them into three categories, one of which has the molecular hallmarks and shortened survival of glioblastoma multiforme, ...
Not all attacks are created equal [Published Multiple Sclerosis Research - Apr 04 2014]
Hidaka Y, Inaba Y, Matsuda K, Itoh M, Kaneyama T, Nakazawa Y, Koh CS, Ichikawa M. Cytokine production profiles in chronic relapsing-remitting experimental autoimmune encephalomyelitis: IFN-γ and TNF-α are important participants in the first attack but ...
PML: are stem cells and B cells a trojan horse? [Published Multiple Sclerosis Research - Apr 01 2014]
Are we beginning to understand how PML develops in MSers on natalizumab? #MSBlog #MSResearch "The following paper may prove to be important and needs to be repeated. Bone marrow stem cells, which are responsible for making blood cells, are kept in their ...
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