Population Genetics

Type: Keyphrase
Name: Population Genetics
First reported Jun 25 2014 - Updated Jun 25 2014 - 1 reports

Fish Genes and Climate from Medieval to Modern Times

ReferenceOlafsdottir, G.A., Westfall, K.M., Edvardsson, R. and Palsson, S. 2014. Historical DNA reveals the demographic history of Atlantic cod (Gadus morhua) in medieval and early modern Iceland. Proceedings of the Royal Society B 281 : 10.1098/r ... [Published CO2 Science - Jun 25 2014]
First reported Jun 19 2014 - Updated Jun 19 2014 - 1 reports

Loss-of-Function Mutations in APOC3, Triglycerides, and Coronary Disease

Supported by the Grand Opportunity (GO) Exome Sequencing Project (ESP), through which grants were provided by the NHLBI (RC2 HL-103010 [HeartGO], RC2 HL-102923 [LungGO], RC2 HL-102924 [Women's Health Initiative ESP], RC2 HL-102925 [BroadGO], and RC2 HL-102926 ... [Published New England Journal of Medicine - Jun 19 2014]
First reported Jun 16 2014 - Updated Jun 16 2014 - 1 reports

BRCA2 Gene Now Connected to Lung Cancer, Doubling a Smoker's Risk

New research confirms a vulnerability to lung cancer can be inherited and implicates the BRCA2 gene as harboring one of the involved genetic mutations. An international consortium of scientists including investigators at the Institute for Cancer Research ... [Published Advance for Administrators of the Laboratory - Jun 16 2014]

Quotes

...8 times," said study leader Richard Houlston, professor of Molecular and Population Genetics at The Institute of Cancer Research (ICR). "Smokers in general have nearly a 15 per cent chance of developing lung cancer, far higher than in non-smokers. Our results show that some smokers with BRCA2 mutations are at an enormous risk of lung cancer - somewhere in the region of 25 per cent over their lifetime. Lung cancer claims more than a million lives a year worldwide and is by far the biggest cancer killer in the UK. We know that the single biggest thing we can do to reduce death rates is to persuade people not to smoke, and our new findings make plain that this is even more critical in people with an underlying genetic risk."
"But we have shown that you cannot assume that raising HDL by any mechanism will help patients. Perhaps other mechanisms exist that can lower risk, but we will need to keep searching for them" Kathiresan added

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Fish Genes and Climate from Medieval to Modern ... [Published CO2 Science - Jun 25 2014]
Loss-of-Function Mutations in APOC3, Triglyceri... [Published New England Journal of Medicine - Jun 19 2014]
BRCA2 Gene Now Connected to Lung Cancer, Doubli... [Published Advance for Administrators of the Laboratory - Jun 16 2014]
Raising `good cholesterol` may not always cut h... [Published Topnews.in - May 17 2012]
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