Type: Keyphrase
Name: Proteinuria
First reported Sep 19 2014 - Updated Sep 19 2014 - 1 reports

Wedbush Securities Reacts To Regulus Therapeutics Inc Announcing ATHENA Natural History Study

In a report published Friday, Wedbush Securities analyst Liana Moussatos reiterated an Outperform rating and $19.00 price target on Regulus Therapeutics Inc (NASDAQ: RGLS).In the report, Wedbush Securities noted, “Regulus announced the initiation of the ... [Published - Sep 19 2014]
First reported Sep 18 2014 - Updated Sep 18 2014 - 1 reports

Multicenter prospective clinical study to evaluate the prediction of short-term outcome in pregnant women with suspected preeclampsia (PROGNOSIS): study protocol

Study protocolMartin Hund , Deirdre Allegranza , Maria Schoedl , Peter Dilba , Wilma Verhagen-Kamerbeek and Holger StepanBMC Pregnancy and Childbirth 2014, 14 :324doi:10.1186/1471-2393-14-324Published: 18 September 2014Abstract (provisional) Backgro ... [Published BMC - Sep 18 2014]
First reported Sep 18 2014 - Updated Sep 18 2014 - 1 reports

GALECTIN THERAPEUTICS : Patent Issued for Galactose-Pronged Carbohydrate Compounds for the Treatment of Diabetic Nephropathy and Associated Disorders

By a News Reporter-Staff News Editor at Life Science Weekly -- A patent by the inventors Traber, Peter G. ( Norcros , GA); Zomer, Eliezer ( Newton, MA ), filed on October 10, 2013 , was published online on September 9, 2014 , according to news reporting ... [Published 4 Traders - Sep 18 2014]
First reported Sep 17 2014 - Updated Sep 17 2014 - 1 reports

Rare hereditary COL4A3/COL4A4 variants may be mistaken for familial focal segmental glomerulosclerosis

To read this article in full you may need to log in, make a payment or gain access through a site license (see right).Kidney International , (17 September 2014) | doi :10.1038/ki.2014.305Rare hereditary COL4A3 / COL4A4 variants may be mistaken for familial ... [Published Kidney International - Sep 17 2014]
First reported Sep 12 2014 - Updated Sep 13 2014 - 1 reports

Lilly Announces CYRAMZA™ Phase III Second-Line Colorectal Cancer Trial Meets Primary Endpoint of Overall..

The most commonly reported adverse reactions (all grades; grade 3-4) occurring in ≥5% of patients receiving CYRAMZA and >/=2% higher than placebo in Study 1 were hypertension (16% vs 8%; 8% vs 3%), diarrhea (14% vs 9%; 1% vs 2%), headache (9% vs 3%; ... [Published ADVFN India - Sep 12 2014]
First reported Sep 12 2014 - Updated Sep 12 2014 - 1 reports

Switch From RTV to COBI To Boost a PI With Moderate Kidney Impairment

ICAAC 2014 54th Interscience Conferenceon Antimicrobial Agents and ChemotherapySeptember 5-9, 2014, Washington, DC ICAAC 2014. September 5-9, 2014. Washington, DC ICAAC: - (09/09/14) Mark MascoliniAmong people with moderate renal impairment (creatinine ... [Published National AIDS Treatment Advocacy Project - Sep 12 2014]
First reported Sep 09 2014 - Updated Sep 09 2014 - 1 reports

Carbon Monoxide Prevents Hypertension and Proteinuria in an Adenovirus sFlt-1 Preeclampsia-Like Mouse Model

by Carolina C. Venditti, Richard Casselman, Iain Young, S. Ananth Karumanchi, Graeme N. SmithPreeclampsia (PE) remains a leading cause of maternal and neonatal morbidity and mortality worldwide. Smoking cigarettes is associated with a decreased incidence ... [Published - Sep 09 2014]
First reported Sep 06 2014 - Updated Sep 06 2014 - 1 reports

The Protective Role of Fucosylated Chondroitin Sulfate, a Distinct Glycosaminoglycan, in a Murine Model of Streptozotocin-Induced Diabetic Nephropathy

by Conrado L. R. Gomes, Cristina L. Leão, Carolina Venturotti, André L. Barreira, Gabriela Guimarães, Roberto J. C. Fonseca, Rodrigo S. Fortunato, Paulo A. S. Mourão, Alvimar G. Delgado, Christina M. Takiya, Maurilo LeiteBackgroundHeparanase-1 activation, ... [Published - Sep 06 2014]
First reported Sep 03 2014 - Updated Sep 03 2014 - 1 reports

One Last Chance For Chemocentryx's Star Diabetes Candidate

Summary Chemocentryx released 12-week phase 2 data on its diabetic kidney disease drug CCX140 last year, and they were underwhelming. 52-week data are due next quarter. Nevertheless, the results were positive for a subgroup that Chemocentryx is being ... [Published Seeking Alpha - Sep 03 2014]
First reported Aug 28 2014 - Updated Aug 28 2014 - 1 reports

The Calcineurin Inhibitor Tacrolimus Reduces Proteinuria in Membranous Nephropathy Accompanied by a Decrease in Angiopoietin-Like-4

by Lei Peng, Jing Ma, Rui Cui, Xiao Chen, Shi-Yao Wei, Qiu-Ju Wei, Bing LiTacrolimus is an anticalcineurinic agent with potent immunosuppressive activity that has recently been shown to have the added benefit of reducing proteinuria in membranous nephropathy ... [Published - Aug 28 2014]
First reported Aug 28 2014 - Updated Aug 28 2014 - 1 reports

The Long-Term Consequences of Preeclampsia

Hypertension After Preeclampsia Is Preceded by Changes in Cardiac Structure and FunctionGhossein-Doha C, Peeters L, van Heijster S, et alHypertension . 2013;62:382-390Preeclampsia is a serious event in a pregnancy, with the potential for bad outcomes. ... [Published - Aug 28 2014]
First reported Aug 24 2014 - Updated Aug 24 2014 - 1 reports

Dietary acid load and chronic kidney disease among adults in the United States

Diet can markedly affect acid-base status and it significantly influences chronic kidney disease (CKD) and its progression. The relationship of dietary acid load (DAL) and CKD has not been assessed on a population level.We examined the association of ... [Published 7thSpace - Aug 24 2014]


...73m2 should likely not be prescribed tenofovir - there are many different ART options, so why risk toxicity?" said Dr. Lucas. "Also, patients who are on tenofovir should be taken off if there is a clinically significant drop in kidney function, and placed on another therapy."
...oncology, hematology with the Center for Palliative Care at Kliniken Essen-Mitte in Germany, and principal investigator of the RAINBOW trial. "Currently, there is a significant need for effective therapies to help combat this deadly disease and ramucirumab in this combination could provide a valuable second-line treatment option." renal function and time to end-stage renal disease in patients with Alport syndrome," said Paul Grint , M D , Chief Medical Officer of Regulus.  "The data from ATHENA will be important to the Alport syndrome patient community and Regulus' future success in treating the disease with RG-012, a key program under our 'Clinical Map Initiative'."
"In some embodiments the compound can be produced by a process comprising depolymerization catabolized by targeted peroxidation cleavage of glycosidic bonds by ionized OH sup- generated from ascorbic acid and/or peroxide in presence or absence of additional reduced form of a transition metal ion, like Cu sup.++. at 1 to 100 mM. Other transition metals like Ca. sup.++ or Fe.sup.++ can also be used for this purpose."

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Follow-up of Blood-Pressure Lowering and Glucos... [Published New England Journal of Medicine - Sep 20 2014]
Wedbush Securities Reacts To Regulus Therapeuti... [Published - Sep 19 2014]
Alnylam (ALNY) to File Clinical Trial Applicati... [Published Yahoo! Finance - Sep 18 2014]
HIVMA/IDSA guidelines: Antiretroviral therapies... [Published Medical News Today - Sep 18 2014]
CYRAMZA™ In Combination With Paclitaxel Signif... [Published - Sep 18 2014]
Regulus Initiates ATHENA Natural History of Dis... [Published ADVFN India - Sep 18 2014]
Multicenter prospective clinical study to evalu... [Published BMC - Sep 18 2014]
GALECTIN THERAPEUTICS : Patent Issued for Galac... [Published 4 Traders - Sep 18 2014]
Bone Disease in Newly Diagnosed Lupus Nephritis... [Published - Sep 17 2014]
Rare hereditary COL4A3/COL4A4 variants may be m... [Published Kidney International - Sep 17 2014]
Alnylam Bolsters Pipeline with ALN-AGT for the ... [Published - Sep 17 2014]
ICAAC 2014: Cobicistat Long-term Efficacy Match... [Published HIV and - Sep 16 2014]
First Single-Tablet PI Regimen With Darunavir a... [Published National AIDS Treatment Advocacy Project - Sep 16 2014]
Survival benefits with erlotinib plus bevacizum... [Published MedWire News - Sep 16 2014]
Adding Antiangiopoietin Agent Trebananib to Pac... [Published The ASCO Post - Sep 15 2014]
Updated Summary: Antiretroviral therapy. [New Y... [Published National Guideline Clearinghouse - Sep 15 2014]
Exelixis Announces Results from the COMET-1 Pha... [Published Pharmacy Choice - Sep 15 2014]
Norwood native seeks kidney transplant [Published Wicked Local Norwood - Sep 12 2014]
Switch From RTV to COBI To Boost a PI With Mode... [Published National AIDS Treatment Advocacy Project - Sep 12 2014]
VG Life Sciences' Advisor Gives Preeclampsia Pr... [Published Pettinga Financial Advisors - Sep 12 2014]
Lilly Announces CYRAMZA™ Phase III Second-Line ... [Published ADVFN India - Sep 12 2014]
Lilly Announces CYRAMZA™ Phase III Second-Line ... [Published Stockwatch - Sep 12 2014]
Tubulointerstitial nephritis and uveitis syndro... [Published 7thSpace - Sep 12 2014]
Claritas Genomics Launches Next Generation Sequ... [Published Nation's Restaurant News - Sep 11 2014]
Patent Issued for Azetidine Derivatives [Published 4 Traders - Sep 11 2014]
Patent Application Titled "Drug Eluting Scaffol... [Published - Sep 10 2014]
Hives after tetanus serum shot. Was it serum si... [Published HealthBoards - Sep 10 2014]
Prosensa announces 12 presentations at the 19th... [Published 4 Traders - Sep 10 2014]
A simple preventive — aspirin — lowers risk of ... [Published American Council On Science & Health - Sep 09 2014]
Carbon Monoxide Prevents Hypertension and Prote... [Published - Sep 09 2014]
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Hives after tetanus serum shot. Was it serum si... [Published HealthBoards - Sep 10 2014]
Hello,I recieved both tetanus toxoid and serum on June 1st. A week later I had hives and swelling in arms, my overall condition (judging subjectively) was not good, but blood and urine tests were not bad. 44 days after the shots I was able to test IgE, ...
Help me understand my tests? Don't look good [Published HealthBoards - Jul 20 2014]
Hey everybody just registered and I have a few questions regarding my urinalysis. Woke up one morning and noticed foamy urine which made me think huh? Looked it up and boom started freaking out because it points to kidneys. Being that I have hypertension ...
Proteinuria [Published HealthBoards - Jul 16 2014]
Hi,This is my first time here. I'm very worried because I'm 27 and a doctor found protein in my urine. I had this issue when I was 24 and it went away after 4 moths. I had a renal panel done and everything was fine. I got pregnant and my doctors of course ...
Proteinuria [Published HealthBoards - Jun 30 2014]
I had normal kidney function until last February. Not sure what happened, maybe a virus. I remember a really bad frontal headache and severe nausea and maybe some dizziness. But soon after, I had a routine visit to my chiropractor who takes my BP weekly ...
Proteinuria Often Untreated in Hospital [Published - medical news plus CME for ph ... - Apr 24 2014]
LAS VEGAS (MedPage Today) -- Although it's easily managed, proteinuria often goes untreated in the hospital, researchers reported here. ...
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