rapamycin

Type: Keyphrase
Name: rapamycin
First reported Sep 19 2014 - Updated Sep 19 2014 - 1 reports

MicroPort Promotes Firehawk® in TCT 2014

- Shanghai MicroPort Medical (Group) Co ("MicroPort") attended the 26th Transcatheter Cardiovascular Therapeutics (TCT) held from 13 September to 17 September in Washington DC, to further promote its third-generation Drug Eluting Stent ("DES") Firehawk® ... [Published Noodls - Sep 19 2014]
First reported Sep 16 2014 - Updated Sep 16 2014 - 1 reports

Pancreatic cancer: drug advance

Cancer Research UK scientists at the Cancer Research UK Beatson Institute and the University of Glasgow, have found a new use for an old drug by showing that it shrinks a particular type of pancreatic cancer tumour and stops it spreading.Mice with pancreatic ... [Published Clinical Services Journal - Sep 16 2014]
First reported Sep 09 2014 - Updated Sep 09 2014 - 1 reports

Delivering the genes

LA JOLLA, Calif.—In a new study led by Associate Prof. Bruce Torbett of , a team of researchers have cleared a major hurdle by solving the puzzle of how to bypass blood stem cells’ natural defenses and more efficiently insert disease-fighting genes into ... [Published Drug Discovery News - Sep 09 2014]
First reported Sep 09 2014 - Updated Sep 09 2014 - 1 reports

Local vascular delivery of topotecan in combination with rapamycin to prevent restenosis following vascular injury

Medical devices, in particular implantable medical devices, may be coated to minimize or substantially eliminate a biological organism's reaction to the introduction of the medical device to the organism. The medical devices may be coated with any number ... [Published Free Patents Online - Sep 09 2014]
First reported Sep 03 2014 - Updated Sep 03 2014 - 1 reports

Sirolimus: A Therapeutic Advance for Dermatologic Disease

Sehgal SN. Sirolimus: its discovery, biological properties, and mechanism of action. Transplant Proc. 2003 May;35(3 Suppl):7S-14S.Del Bufalo D, Ciuffreda L, Trisciuoglio D, et al. Antiangiogenic potential of the Mammalian target of rapamycin inhibitor ... [Published General Medicine eJournal - Sep 03 2014]
First reported Sep 02 2014 - Updated Sep 02 2014 - 1 reports

Immunohistochemical Analysis of the Mechanistic Target of Rapamycin and Hypoxia Signalling Pathways in Basal Cell Carcinoma and Trichoepithelioma

by Tjinta Brinkhuizen, Chantal A. H. Weijzen, Jonathan Eben, Monique R. Thissen, Ariënne M. van Marion, Björn G. Lohman, Véronique J. L. Winnepenninckx, Patty J. Nelemans, Maurice A. M. van SteenselBackgroundBasal cell carcinoma (BCC) is the most common ... [Published Plosone.org - Sep 02 2014]
First reported Aug 29 2014 - Updated Aug 30 2014 - 3 reports

Study Explores Use of Rapamycin and FK506 for Peripheral Nerve Repair

Researchers are now focusing on areas such as nerve repair and use of stem cell therapy for the same.FK506 possesses a well-studied neuroregenerative effect, stimulating neurite extension in the presence of nerve growth factor in vitro, and enhancing ... [Published MedIndia - Aug 30 2014]
First reported Aug 29 2014 - Updated Aug 29 2014 - 1 reports

New agents and new targets for renal cell carcinoma

The vascular endothelial growth factor (VEGF) pathway blockers and mammalian target of rapamycin (mTOR) inhibitors have dramatically improved the treatment options and outcome for patients with advanced renal cell carcinoma (RCC). 08/29/2014 ... [Published News from Kidney Cancer Association - Aug 29 2014]
First reported Aug 25 2014 - Updated Aug 25 2014 - 2 reports

Synaptic Pruning Improves Autism in Mice

WIKIMEDIA, As toddlers’ brains develop, they among neurons, a process that continues through adolescence. Previous studies have suggested that synapse structure and density might be abnormal in people with autism and in animal models of the disorder.A ... [Published The Scientist - Aug 25 2014]
First reported Aug 23 2014 - Updated Aug 23 2014 - 6 reports

Study suggests treatment option for autism patients

AFPWASHINGTON--People with autism have too many synapses — the connectors by which brain cells send and receive signals — according to a new study that may point to a treatment for the complex disorder.The extra synapses in autistic brains are the result ... [Published China Post - Aug 23 2014]
First reported Aug 21 2014 - Updated Aug 22 2014 - 13 reports

Children with autism 'have too many synapses in their brain'

Ratings require JavaScript to be enabled. A new study by researchers from the Columbia University Medical Center in New York, NY, finds that children and adolescents with autism have too many synapses in their brain, which can affect their brain ... [Published Medical News Today - Aug 22 2014]
First reported Aug 21 2014 - Updated Aug 21 2014 - 1 reports

Existing drug offers new hope in a subtype of pancreatic cancer

Share this article:A new use for an old drug shrinks a particular type of pancreatic cancer and stops it from spreading, according to new research."This is incredibly important research showing for the first time that there's potential to tailor treatment ... [Published Chemotherapy Advisor - Aug 21 2014]

Quotes

...development to make Firehawk® the lowest drug dosage DES in the world," said Qiyi Luo, Chief Technology Officer of MicroPort Scientific Corporation. "After launched in China, Firehawk® has helped in improving life quality of many Chinese patients. We hope to take this opportunity of TCT to bring this revolutionary product to the international market to help more patients around the world."
"The formulations of the present invention all contain ISA.sub.Tx247 as the active ingredient and synthetic or vegetable oils emulsified with a synthetic co-emulsifier such as a non-ionic surfactant that has a polyoxylated moiety. Thus, the present formulations contain ISA.sub.Tx247, a surfactant, ethanol, a lipophilic and/or an amphiphilic solvent. The formulations of the present invention may be adjusted for pH and isotonicity as needed, and may also include biocompatable polymers such as protective colloids, suspension stabilizers and building agents, excipients, binders and carriers, as needed."

More Content

All (134) | News (105) | Reports (0) | Blogs (29) | Audio/Video (0) | Fact Sheets (0) | Press Releases (0)
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MicroPort Promotes Firehawk® in TCT 2014 [Published Noodls - Sep 19 2014]
Researchers Submit Patent Application, "Cyclosp... [Published 4 Traders - Sep 17 2014]
Muscle Gene Expression Patterns in Human Rotato... [Published Journal of Bone and Joint Surgery - Sep 17 2014]
Phosphorylation of ribosomal protein S6 mediate... [Published Kidney International - Sep 17 2014]
Pancreatic cancer: drug advance [Published Clinical Services Journal - Sep 16 2014]
Neuroendocrine Tumors: Answers—and Questions [Published Cancernetwork.com - Sep 16 2014]
mTORC1 Is Essential for Early Steps during Schw... [Published Plosone.org - Sep 15 2014]
An Update on Gastroenteropancreatic Neuroendocr... [Published Cancernetwork.com - Sep 15 2014]
Investigators from Goethe-University Report New... [Published 4 Traders - Sep 10 2014]
How can sitting too much give you breast cancer? [Published Examiner.com - Sep 10 2014]
Delivering the genes [Published Drug Discovery News - Sep 09 2014]
Treatment patterns in metastatic renal cell car... [Published UroToday - Sep 09 2014]
PF-4708671 Activates AMPK Independently of p70S... [Published Plosone.org - Sep 09 2014]
Local vascular delivery of topotecan in combina... [Published Free Patents Online - Sep 09 2014]
Patent Issued for Nutritional Intervention for ... [Published 4 Traders - Sep 05 2014]
Patent Application Titled "Deuterated Cyclospor... [Published 4 Traders - Sep 05 2014]
Calico Partnering with AbbVie [Published Fight Aging! - Sep 04 2014]
Intestinal Cell Kinase Is a Novel Participant i... [Published Plosone.org - Sep 03 2014]
mTOR Inhibition Induces Compensatory, Therapeut... [Published News from Kidney Cancer Association - Sep 03 2014]
mTOR Inhibition Induces Compensatory, Therapeut... [Published Plosone.org - Sep 03 2014]
The Very Real Risks of Consuming Too Much Protein [Published Mercola - Sep 03 2014]
Sirolimus: A Therapeutic Advance for Dermatolog... [Published General Medicine eJournal - Sep 03 2014]
Autistic Youngsters Found to Have Too Many Brai... [Published Biotech Daily - Sep 03 2014]
Method for synthesizing temsirolimus [Published Free Patents Online - Sep 03 2014]
Amino Acid Supplementation Affects Imprinted Ge... [Published Plosone.org - Sep 02 2014]
Immunohistochemical Analysis of the Mechanistic... [Published Plosone.org - Sep 02 2014]
Adenosine-Mono-Phosphate-Activated Protein Kina... [Published Plosone.org - Sep 02 2014]
Court Report - August 2014 #5 [Published JD Supra - Sep 02 2014]
EIF4F affects dexamethasone response in myeloma... [Published PNAS - Sep 02 2014]
Study Explores Use of Rapamycin and FK506 for P... [Published MedIndia - Aug 30 2014]
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Calico Partnering with AbbVie [Published Fight Aging! - Sep 04 2014]
This isn't terribly newsworthy, as it doesn't really do more than reinforce current views on the direction that will be taken by Calico, and deals of this nature were a given at some point in this process. It is my hope that Calico turns out to be something ...
mTOR Inhibition Induces Compensatory, Therapeut... [Published News from Kidney Cancer Association - Sep 03 2014]
Rapamycin derivatives allosterically targeting mTOR are currently FDA approved to treat advanced renal cell carcinoma (RCC), and catalytic inhibitors of mTOR/PI3K are now in clinical trials for treating various solid tumors. 09/03/2014 ...
New agents and new targets for renal cell carci... [Published News from Kidney Cancer Association - Aug 29 2014]
The vascular endothelial growth factor (VEGF) pathway blockers and mammalian target of rapamycin (mTOR) inhibitors have dramatically improved the treatment options and outcome for patients with advanced renal cell carcinoma (RCC). 08/29/2014 ...
Liver ATF4 Upregulation Common to Many of the R... [Published Fight Aging! - Aug 27 2014]
There are a score or more ways to reliably slow aging in mice , methods that include a few classes of drug, various single gene alterations, and calorie restriction . The most exceptional of these methods extends life by 60% or so, but most are in ...
Studying Calorie Restriction and Rapamycin [Published Fight Aging! - Aug 12 2014]
Here is an example of the sort of work presently taking place in many of the labs interested in aging and longevity, consisting of exploration of existing drugs shown to have some effect on life span in animal studies, alongside continued research into ...
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