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Retinal

Type: Keyphrase

Name: Retinal

First reported 31 mins ago - Updated 31 mins ago - 1 reports

RNA-Binding Protein Hermes/RBPMS Inversely Affects Synapse Density and Axon Arbor Formation in Retinal Ganglion Cells In Vivo

Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge CB2 3DY, United KingdomAuthor contributions: H.H., F.W.-v.H., D.M., W.A.H., and C.E.H. designed research; H.H., F.W.-v.H., D.M., M.Z., and H.S. performed research; ... [Published Journal of Neuroscience - 31 mins ago]

Entities: Ganglion, Retinal, Protein, Synapse, Axon Holdings SA

First reported 46 mins ago - Updated 46 mins ago - 1 reports

Finding and treating the cause of inherited blindness

European scientists have made a major breakthrough in the treatment of inherited retinal diseases. Many disorders which cause blindness are due to mutations in genes that are expressed in the photoreceptor cells of the retina which process light. The ... [Published Cordis - 46 mins ago]

Entities: Gene Therapy, Retinal, Clinical trials, gene transfer

First reported 4 hours ago - Updated 4 hours ago - 1 reports

New technologies for retinal therapies

The future of the investigation and treatment of retinal disorders is already here at the MedUni Vienna: in the new Christian Doppler "OPTIMA" (Ophthalmic Image Analysis) laboratory headed by Ursula Schmidt-Erfurth, Director of the University Department ... [Published Medical Xpress - 4 hours ago]

Entities: Retinal, tomography, Vienna, CHRISTIAN DOPPLER

First reported Jun 18 2013 - Updated 4 hours ago - 2 reports

Wireless subretinal prostheses allows blind mice to see light

Photovoltaic array with 70 µm pixels placed on top of the retinal pigmented epithelium in the eye. Color insert: fundus photo of a rat eye with subretinally implanted photovoltaic array with 140 µm pixels. Credit:Palanker Lab, Stanford University, CA(Medical ... [Published Medical Xpress - 4 hours ago]

Entities: Retinal, Neuron, Photovoltaic

First reported 5 hours ago - Updated 5 hours ago - 1 reports

Taliban

Afghan president: No peace talks with the Taliban unless only Afghans involved, violence stops

LIHUE — Kauai residents can get free retinal screenings through the Vision Van and the Lions Clubs of District 50 from June 21 to June 3 ... [Published Kauai Garden Island News - 5 hours ago]

Entities: Peace Talks, Taliban, Retinal

First reported 19 hours ago - Updated 19 hours ago - 1 reports

How to Make a Bionic Eye: Try a Little Engineering Vision

PHILADELPHIA, June 18—Whether you’re planning to market a pacemaker, an artificial hip or knee, or a cochlear implant, design considerations are of the utmost importance from the ground up. This was the takeaway message from the MD&M East MedTech Innovate ... [Published QMED - 19 hours ago]

Entities: Robert Greenberg, Electrode, Platinum, Retinal

First reported 20 hours ago - Updated 20 hours ago - 1 reports

MD Stem Cells Shows Retinal Eye Disease Responds to Stem Cells With Significant Vision Improvement

Blinding retinal eye disease called Retinitis Pigmentosa seen to make major gains in visual acuity following adult stem cell therapy in the United States. Online PR News 18-June-2013 Losing your vision slowly but progressively is one the most frightening ... [Published Online PR News - 20 hours ago]

Entities: Stem Cell, Retinal, Adult Stem Cell, bone marrow, Patient

First reported Jun 17 2013 - Updated Jun 18 2013 - 2 reports

Professor's coatings could help medical implants function better

A small sensor like these are used to monitor bodily functions or deliver drugs. Produced by a collaborator group at the University of Technology in Dresden, Germany, the sensors were coated with thin layers of customized block copolymers in Dr. Carmen ... [Published PhysOrg.com - Jun 18 2013]

Entities: Implants, University of Alabama in Huntsville, Polymer, Immune System

First reported Jun 18 2013 - Updated Jun 18 2013 - 1 reports

Mutant virus used to treat blindness

Scientists have discovered and amplified an evolved adeno-associated virus (AAV) to target and deliver gene therapy to retinal cells in mice. This discovery could lead to less invasive and more precise gene therapies for retinal degeneration diseases ... [Published GMA News.tv - Jun 18 2013]

Entities: Gene Therapy, Retinal, Virus

First reported Jun 18 2013 - Updated Jun 18 2013 - 1 reports

ARVO 2013 Wrap-up: Noteworthy Retinal News

This year's meeting provided a wealth of new data and promising therapies for retinal specialists.Medscape Ophthalmology ... [Published Medscape - Jun 18 2013]

Entities: Retinal, Medscape, Ophthalmology

First reported Jun 17 2013 - Updated Jun 17 2013 - 1 reports

Blood Vessels in the Eye Linked With IQ

The width of blood vessels in the retina, located at the back of the eye, may indicate brain health years before the onset of dementia and other deficits, according to a new study published in Psychological Science, a journal of the Association for Psychological ... [Published Eyesmart - Jun 17 2013]

Entities: Vessel, Retinal, Oxygen, Dunedin (New Zealand), Age-Related

First reported Jun 17 2013 - Updated Jun 17 2013 - 1 reports

Market Snapshot: Diabetic Macular Edema, Another Blockbuster Opportunity For Retinal Drugs?

Having relatively rapidly built a multi-billion dollar market in wet age-related macular degeneration, biotech and pharma companies may be about to repeat the exercise with diabetic macular edema, a complication of diabetes that’s growing in importance ... [Published The Rose Sheet - Jun 17 2013]

Entities: Diabetic Macular Edema, Retinal, Drugs, Wet Age-related Macular Degeneration

Quotes

...The European AAVEYE ( "Gene Therapy for Inherited Severe Photoreceptor Diseases') project set outout to develop gene transfer techniques for the photoreceptor neurons in the retina using a virus (adeno-associated virus, AAV) as a form of transport. The team focused on pre-clinical proof-of-concept (POC) gene therapy strategies to tackle these debilitating diseases. Over the course of three years, an international consortium from the UK, Switzerland, Italy and Estonia worked on the project coordinated by Fondazione Telethon TIGEM, in Italy. With EU-funding of nearly EUR 3 million the subsequent research involved specialists in the fields of AVV-mediated gene transfer to the retina, the pathogenesis of photoreceptor degeneration, and design of molecular diagnostics for inherited retinal diseases. Professor of medical genetics, Alberto Auricchio from TIGEM who has been leading the project says: 'The main highlight of the project has been the identification of a vector platform for retinal photoreceptor gene therapy. This will help people with blinding conditions which require gene therapy directed to the photoreceptors.' During the course of the project, the AAVEYE team also demonstrated that the viral vector based on adeno-associated virus serotype 8 (AAV2/8) is the most efficient way to transfer genes to photoreceptors of rodents and large animals. They also developed a way of significantly slowing down the degeneration of photoreceptors and restoring retina function. In addition, the project has generated a considerable amount of pre-clinical data, which will be used for future clinical trials. The professor explains: 'A clinical trial is not a simple endeavour; you need a significant amount of funding. Once we have new funding opportunities to cover a clinical trial for these rare disorders, then we will be ready to start the next stage.' Meanwhile Professor Auricchio continues to work on gene therapy approaches for retinal degeneration, and is involved in the coordination of a clinical trial (which is also funded by the European Union) for a rare inherited disease called mucopolysaccharidosis VI."

Finding and treating the cause of inherited blindness [Published Cordis - 46 mins ago]

...of optical coherence tomography it is possible to identify disorders of the retina in high resolution detail – and to do so at a very early stage: "With this we can look directly into the retinal layers non-invasively and discover the slightest changes early." OCT is an imaging process, which – like ultrasound technology, but without any physical contact whatsoever – can produce high resolution sectional images...

New technologies for retinal therapies [Published Medical Xpress - 4 hours ago]

Mr Meeke said: "The CT scan showed bleeding over the surface of Kaydon's brain at a number of different sites."

Closing statements at baby murder court case [Published This is Cornwall - 6 hours ago]

“We have early results to report on patients treated with BMSC adult stem cells” indicates Dr. Levy, President of MD Stem Cells. "Normal vision is considered 20/20. The Snellen Eye Chart defines vision by comparing the top number of a normal eye to the bottom number of the patient - the larger the bottom number, the poorer the vision. We can also convert to decimal for comparison purposes. Both our patients had experienced severe visual loss. One patient was Count Fingers at 3 feet in both eyes or in Snellen Acuity 20/2666 (decimal .007). The other had Hand Motion or what would be considered about Snellen Acuity 20/20,000 (decimal .001) in one eye and 20/60 (.3) in the other."

MD Stem Cells Shows Retinal Eye Disease Responds to Stem Cells With Significant Vision Improvement [Published Online PR News - 20 hours ago]

More Content

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RNA-Binding Protein Hermes/RBPMS Inversely Affe... [Published Journal of Neuroscience - 31 mins ago]
Finding and treating the cause of inherited bli... [Published Cordis - 46 mins ago]
Wireless subretinal prostheses allows blind mic... [Published Medical Xpress - 4 hours ago]
New technologies for retinal therapies [Published Medical Xpress - 4 hours ago]
Afghan president: No peace talks with the Talib... [Published Kauai Garden Island News - 5 hours ago]
Closing statements at baby murder court case [Published This is Cornwall - 6 hours ago]
Want to buy one of London's mega mansions? You'... [Published London Evening Standard - 6 hours ago]
Usher Syndrome [Published MedIndia - 7 hours ago]
Interesting Facts About the Portuguese Water Dog [Published Buzzle.com - 13 hours ago]
BIODIEM LTD.: BioDiems Asia Biotech Invest 2013... [Published 4 Traders - 15 hours ago]
Major health care providers [Published Individual.com - 18 hours ago]
Zavalla man sentenced to 10 years for admittedl... [Published Lufkin Daily News - 18 hours ago]
New Faces at the SENS Research Foundation [Published Fight Aging! - 19 hours ago]
How to Make a Bionic Eye: Try a Little Engineer... [Published QMED - 19 hours ago]
MD Stem Cells Shows Retinal Eye Disease Respond... [Published Online PR News - 20 hours ago]
Ten more e-gates to be installed at Dubai Inter... [Published Passenger Terminal Today - 21 hours ago]
Researchers develop easy, effective therapy to ... [Published UC Newswire - 22 hours ago]
News in Brief: Eye chip sends signals to blind ... [Published Science News Online - 23 hours ago]
Excerpt From '2312' [Published Popular Science - Jun 18 2013]
New Virus Delivery Method Could Help Treat Blin... [Published Yahoo! News - Jun 18 2013]
Seeing the Light: Retinal Prosthesis Restores R... [Published LiveScience.com - Jun 18 2013]
Bayer HealthCare announces positive results fro... [Published Individual.com - Jun 18 2013]
Professor's coatings could help medical implant... [Published PhysOrg.com - Jun 18 2013]
iCo Therapeutics Inc Updates On iDEAL Phase 2 S... [Published Reuters - Jun 18 2013]
Mutant virus used to treat blindness [Published GMA News.tv - Jun 18 2013]
PHOTOS: Top 9 PREMIUM tablets [Published rediff.com - Jun 18 2013]
Lawless NSA Global Spying [Published NYC Independent Media Center - Jun 18 2013]
Red flag symptoms: Hypertension [Published GP Online - Jun 18 2013]
ARVO 2013 Wrap-up: Noteworthy Retinal News [Published Medscape - Jun 18 2013]
Could playing indoors harm your children's vision? [Published KLTV 7 - Jun 17 2013]

Blogs

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New Faces at the SENS Research Foundation [Published Fight Aging! - 19 hours ago] The SENS Research Foundation advocates, organizes, and funds rejuvenation research based on the Strategies for Engineered Negligible Senescence (SENS) program . The aim is to produce the means to repair and reverse the fundamental known differences ...
Vitrectomy Issues [Published HealthBoards - Jun 17 2013] I underwent a vitrectomy approximately 4 weeks ago due to a retinal tear and detachment in my left eye. The gas bubble has begun receding, but am having a hard time keeping both eyes open due to the double vision I am experiencing. I can focus on an object ...
[Seminar] Retinopathy of prematurity [Published The Lancet online - Jun 17 2013] The immature retinas of preterm neonates are susceptible to insults that disrupt neurovascular growth, leading to retinopathy of prematurity. Suppression of growth factors due to hyperoxia and loss of the maternal–fetal interaction result in an arrest ...
Scientists Evolve A Virus So It Can Deliver Gen... [Published FuturePundit - Jun 15 2013] Technology review headline: Virus That Evolved in the Lab Delivers Gene Therapy into the Retina. Works for mice. The scientists are now trying to make it work as well for monkeys. From millions of random mutations, scientists identify a virus that could ...
The Science Today: A Salmon Opera [Published The Stranger, Seattle's Only Newspaper - Jun 13 2013] Posted by science intern Madeline Reddington Today, science uses a virus to help restore sight to the blind, learns something new about thought-controlled technology, joins Seattle’s Infinity Box Theatre Project in exploring the future of artificial ...

Audio/Video

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Retinal implant brings sight to the blind [Published Reuters Video: Business - Feb 13 2013]
Retinal implant brings sight to the blind [Published Reuters Video: Technology - Feb 13 2013]
Have Scientists Created a Bionic Eye? [Published WSJ.com Video - Business - Jan 28 2013]

Press Releases

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New App Aims to Help Kids Understand Cancer [Published PR inside - Jun 04 2013]
Canon U.S.A. Announces New CR-2 Plus AF Digital... [Published Business Wire Health News - Jun 04 2013]
Atheer Pioneers the Mobile 3D Platform of the F... [Published Business Wire - May 30 2013]
Colorado BioScience Association Commends Boettc... [Published PR.com - May 30 2013]
OptiMedica Wins Prestigious 2013 Red Herring 10... [Published Business Wire - May 29 2013]