sirna

Type: Keyphrase
Name: sirna
First reported 15 hours ago - Updated 40 mins ago - 1 reports

Drug Cured 16 of 16 Monkeys with Viral Ebola Relative

A n experimental drug saved the lives of 16 of 16 monkeys with the Marburg virus, a killer near-indistinguishable from Ebola, just as symptoms broke out, said a new study.Thomas Geisbert, senior author of the new Science Translational Medicine study, ... [Published Drug Discovery and Development - 15 hours ago]
Entities: Drugs, Ebola, Virus, sirna, ZMapp
First reported 18 hours ago - Updated 15 hours ago - 1 reports

Running Interference

In Guinea, West Africa, February is the dry season; a dusty haze, stirred by the northeasterly harmattan winds, thickens the air. This year, the winds were harbingers of ill omen. That same month, Guineans began falling ill with symptoms ranging from ... [Published The Chemical Institute of Canada - 18 hours ago]
First reported Aug 26 2014 - Updated Aug 26 2014 - 1 reports

Methods and compositions for the specific inhibition of beta-catenin by double-stranded RNA

This invention relates to compounds, compositions, and methods useful for reducing β-catenin target RNA and protein levels via use of dsRNAs, e.g., Dicer substrate siRNA (DsiRNA) agents. ... [Published Free Patents Online - Aug 26 2014]
Entities: sirna, RNA, Substrate
First reported Aug 22 2014 - Updated Aug 23 2014 - 2 reports

Marburg virus drug shows promise

Filoviruses cause two types of viral haemorrhagic fever: Marburg and Ebola. Ebola has recently taken due a critically high number of deaths in Africa; however, infection with . Marburg virus (MARV) causes severe disease in humans and nonhuman primates. ... [Published Digital Journal - Aug 22 2014]
First reported Aug 23 2014 - Updated Aug 23 2014 - 1 reports

Precise Engineering of siRNA Delivery Vehicles to Tumors Using Polyion Complexes and Gold Nanoparticles

ACS Nano DOI: 10.1021/nn5 ... [Published ACS Nano - Aug 23 2014]
First reported Aug 21 2014 - Updated Aug 21 2014 - 2 reports

WSA Talks to Two Dual-Listed Companies Making Waves

NEW YORK, NY -- (Marketwired) -- 08/21/14 -- Wall Street Analyzer's CEO Interview SeriesBiOasis ( OTCQX: BIOAF ) ( TSX VENTURE: BTI ) released positive quantitative results regarding their newly developed carrier peptide Transcendpep which effectively ... [Published Fat Pitch Financials - Aug 21 2014]
First reported Aug 20 2014 - Updated Aug 21 2014 - 8 reports

Ebola Treatment Using Technique Against Related Virus May Work, Says Study

A boy stands near posters displaying a government message against Ebola at Duwala market in Monrovia. REUTERS/2TangoPositive results from an experimental drug given to monkeys infected with the Marburg virus suggest that the same technique could be useful ... [Published International Business Times UK - Aug 21 2014]
Entities: sirna, Ebola, Virus
First reported Aug 21 2014 - Updated Aug 21 2014 - 2 reports

Data on Cancer Therapy Reported by Researchers at Kyung Hee University (Tumor-specific delivery of siRNA using supramolecular assembly of hyaluronic...

Data on Cancer Therapy Reported by Researchers at Kyung Hee University (Tumor-specific delivery of siRNA using supramolecular assembly of hyaluronic acid nanoparticles and 2b RNA-binding protein/siRNA complexes) By a News Reporter-Staff News Editor at ... [Published Crawford Financial Planning - Aug 21 2014]
First reported Aug 20 2014 - Updated Aug 20 2014 - 2 reports

Alnylam Gets Patent Approval For RNAi-Mediating Molecule

Alnylam Pharmaceuticals’ patent application has been approved by US authorities, as it looks to build on its strong product pipelinePage 1 of 2Published: August 20, 2014 at 5:54 pm EST By: Troy Kuhn Click Ticker to See live coverage ALNYAlnylam Pharmaceuticals ... [Published Bidness Etc - Aug 20 2014]
First reported Aug 20 2014 - Updated Aug 20 2014 - 2 reports

New Small Interference RNAs (siRNAs) Study Findings Recently Were Reported by Researchers at Singapore National University (Redox-Responsive...

New Small Interference RNAs (siRNAs) Study Findings Recently Were Reported by Researchers at Singapore National University (Redox-Responsive Mesoporous Silica Nanoparticles: A Physiologically Sensitive Codelivery Vehicle for siRNA and ...) By a News Reporter-Staff ... [Published Street Sweeper - Aug 20 2014]
First reported Aug 20 2014 - Updated Aug 20 2014 - 1 reports

Ebola virus cousin successfully treated in macaques

Marburg virus, seen here in an electron microscope photo, causes severe and often fatal hemorrhagic fever. (Thomas Geisbert/University of Texas Medical Branch)An experimental type of drug shown to protect rhesus macaques against the Marburg virus could ... [Published CBC - Aug 20 2014]
Entities: Macaque, sirna, Ebola Virus
First reported Aug 20 2014 - Updated Aug 20 2014 - 1 reports

Retired cop Craig Sirna still serving public as successful farmer, entrepreneur: Faces of the Suns (photo gallery)

Craig Sirna of Auburn Township served 34 years as a police officer. He now runs a farm, farm store and pizza restaurant. ... [Published Real-Time News: Latest Northeast Ohio News - cl ... - Aug 20 2014]
Entities: sirna, farmer, Entrepreneur

Quotes

...The findings have been published in the journal Science Translational Medicine, the paper is titled "Marburg virusvirus infection in nonhuman primates: Therapeutic treatment by lipid-encapsulated siRNA."
"Synthetic siRNAs and short hairpin RNAs (shRNAs) can be designed to have identical function. Whereas, siRNA are 2 strands of complementary RNA that can be synthesized, a shRNA is encoded by DNA as a single RNA molecule that hybridze to itself with a loop at one end. The loop is then cleaved intracellularly yielding a molecule similar to a siRNA. There are thousands of RNAi sequences available that are capable of downregulating gene expression. (See, e g. Behlke, 2006, Mol Ther vol. 13 p644). This method has become a universally accepted means of downregulating expression of any gene in mammalian cells."

More Content

All (279) | News (243) | Reports (0) | Blogs (33) | Audio/Video (0) | Fact Sheets (0) | Press Releases (2)
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Drug Cured 16 of 16 Monkeys with Viral Ebola Re... [Published Drug Discovery and Development - 15 hours ago]
Running Interference [Published The Chemical Institute of Canada - 18 hours ago]
Methods and compositions for the specific inhib... [Published Free Patents Online - Aug 26 2014]
Acromegaly and antisense therapy: an interview ... [Published News-Medical.Net - Aug 26 2014]
Therapeutic methods based on tyrosine-substitut... [Published PharmCast - Aug 25 2014]
Precise Engineering of siRNA Delivery Vehicles ... [Published ACS Nano - Aug 23 2014]
Marburg virus drug shows promise [Published Digital Journal - Aug 22 2014]
Inhibition of c-Abl Kinase Activity Renders Can... [Published Plosone.org - Aug 22 2014]
Intermittent Hypoxia Effect on Osteoclastogenes... [Published Plosone.org - Aug 22 2014]
Marburg Drug Shows Promise [Published The Scientist - Aug 22 2014]
At Sirna's Pizzeria in Auburn Township, vegetab... [Published Real-Time News: Latest Northeast Ohio News - cl ... - Aug 22 2014]
Schistosoma japonicum Soluble Egg Antigens Faci... [Published Plosone.org - Aug 22 2014]
Ezrin Mediates Neuritogenesis via Down-Regulati... [Published Plosone.org - Aug 21 2014]
Sympathetic Denervation-Induced MSC Mobilizatio... [Published Plosone.org - Aug 21 2014]
WSA Talks to Two Dual-Listed Companies Making W... [Published Fat Pitch Financials - Aug 21 2014]
WSA Talks to Two Dual-Listed Companies Making W... [Published Pettinga Financial Advisors - Aug 21 2014]
Researchers Submit Patent Application, "Apoptot... [Published 4 Traders - Aug 21 2014]
Ebola Patients Released From Hospital [Published The Guardian Express - Aug 21 2014]
Bright colors of summer [Published KansasCity.com - Aug 21 2014]
Alnylam Receives Notice of Allowance from the U... [Published Intellectual Property News Agency - Aug 21 2014]
Ebola Treatment Using Technique Against Related... [Published International Business Times UK - Aug 21 2014]
Sugar-Based Amphiphilic Polymers for Biomedical... [Published Accounts of Chemical Research - Aug 21 2014]
Data on Cancer Therapy Reported by Researchers ... [Published Crawford Financial Planning - Aug 21 2014]
Data on Cancer Therapy Reported by Researchers ... [Published HispanicBusiness.com - Aug 21 2014]
Researchers Submit Patent Application, "Ddr2 Mu... [Published HispanicBusiness.com - Aug 21 2014]
CORNING : Patent Issued for Extracellular Matri... [Published 4 Traders - Aug 21 2014]
Patent Application Titled "Compounds for Use in... [Published HispanicBusiness.com - Aug 21 2014]
Alnylam Gets Patent Approval For RNAi-Mediating... [Published Bidness Etc - Aug 20 2014]
New Small Interference RNAs (siRNAs) Study Find... [Published Street Sweeper - Aug 20 2014]
Reports Summarize Radiation Therapy Study Resul... [Published HispanicBusiness.com - Aug 20 2014]
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Blogs

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At Sirna's Pizzeria in Auburn Township, vegetab... [Published Real-Time News: Latest Northeast Ohio News - cl ... - Aug 22 2014]
Toppings grown in the fields of the Sirna family farm - about a mile around the corner on Ravenna Road - bring a whole new dimension of freshness the Sirna's pizzas. ...
Retired cop Craig Sirna still serving public as... [Published Real-Time News: Latest Northeast Ohio News - cl ... - Aug 20 2014]
Craig Sirna of Auburn Township served 34 years as a police officer. He now runs a farm, farm store and pizza restaurant. ...
RNA combination therapy for lung cancer offers ... [Published MIT News feed - Aug 14 2014]
Small RNA molecules, including microRNAs (miRNAs) and small interfering RNAs (siRNAs), offer tremendous potential as new therapeutic agents to inhibit cancer-cell growth. However, delivering these small RNAs to solid tumors remains a significant challenge, ...
On Again Off Again RNA for Roche [Published The Big Red Biotech Blog - Aug 05 2014]
Roche bought is way back into RNA therapeutics by shelling out $250 M for Denmark's Santaris and its locked nucleic acid (LNA) platform. Roche may also pay up to another $200 M in milestones should things go smoother this time. This deal represents a ...
Silence Therapeutics encouraged by kidney disea... [Published Proactiveinvestors United Kingdom website - Jul 30 2014]
RNA interference specialist Silence Therapeutics ’s ( LON:SLN ) treatment for delayed graft function in kidney transplants has been shown to be beneficial and tolerated in a phase II trial. Licence holder Quark Pharmaceuticals carried out the trial ...
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Press Releases

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Quark Pharmaceuticals Reports Favorable Results... [Published GlobeNewswire: Acquisitions News - Jul 28 2014]
Quark Announces First Patient Dosed in a Phase ... [Published GlobeNewswire: Acquisitions News - Jun 25 2014]
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