Streptomyces

Type: Keyphrase
Name: Streptomyces
First reported Aug 29 2014 - Updated Aug 29 2014 - 2 reports

Developmental On-Off Switch Identified in Antibiotic Producing Microbes

An on-off switch in a group of soil microbes called Streptomyces that produce more than two-thirds of the world's naturally derived antibiotic medicines has been identified by researchers who hope that the ability to manipulate the switch can lead to ... [Published MedIndia - Aug 29 2014]
First reported Aug 28 2014 - Updated Aug 28 2014 - 1 reports

Small Molecule Acts As On-Off Switch for Nature's Antibiotic Factory

Tells Streptomyces to either veg out or get busy By Bill Hathaway - The immune system is great at making sure infections such as ... Tells Streptomyces to either veg out or get busy ...Children who repeatedly become infected with malaria often experience ... [Published Health Canal - Aug 28 2014]
First reported Aug 28 2014 - Updated Aug 28 2014 - 1 reports

Researchers try to make sure herpes does not find a home

By Bill Hathaway - The immune system is great at making sure infections such as the herpes virus do not repeatedly infect a person, a condition known as a superinfection.Yet how the immune system combats superinfection is not well understood.In the Aug. ... [Published Health Canal - Aug 28 2014]
First reported Aug 27 2014 - Updated Aug 27 2014 - 1 reports

RNA-Seq Analysis Reveals a Six-Gene SoxR Regulon in Streptomyces coelicolor

by Nawar Naseer, Joshua A. Shapiro, Monica ChanderThe redox-regulated transcription factor SoxR is conserved in diverse bacteria, but emerging studies suggest that this protein plays distinct physiological roles in different bacteria. SoxR regulates a ... [Published Plosone.org - Aug 27 2014]
First reported Aug 26 2014 - Updated Aug 26 2014 - 1 reports

6-Deoxy-13-hydroxy-8,11-dione-dihydrogranaticin B, an Intermediate in Granaticin Biosynthesis, from Streptomyces sp. CPCC 200532

Key Laboratory of Biotechnology of Antibiotics of Ministry of Health, Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, People’s Republic of China ... [Published Journal of Natural Products - Aug 26 2014]
First reported Aug 21 2014 - Updated Aug 21 2014 - 1 reports

Function and Evolution of Two Forms of SecDF Homologs in Streptomyces coelicolor

by Zhan Zhou, Yudong Li, Ning Sun, Zhihao Sun, Longxian Lv, Yufeng Wang, Libing Shen, Yong-Quan LiThe general secretion (Sec) pathway plays a prominent role in bacterial protein export, and the accessory component SecDF has been shown to improve transportation ... [Published Plosone.org - Aug 21 2014]
First reported Aug 18 2014 - Updated Aug 19 2014 - 2 reports

Caterpillar extract could one day save your life

As the world cries out for new antibiotics, researchers at the John Innes Centre, in Norwich, are taking a bet on bacteria extracted from the stomachs of giant stick insects, and cinnabar caterpillars with a taste for highly toxic plants.Their work is ... [Published Times Live South Africa - Aug 19 2014]
First reported Aug 17 2014 - Updated Aug 18 2014 - 1 reports

INSIGHT-Extreme medicine: The search for new antibiotics

* World crying out for new antibiotics as superbugs evolve* Scientists seek new chemistry in hard-to-reach places* "Back to nature" search aided by genome mining technologyBy Kate Kelland and Ben HirschlerNORWICH, England, Aug 17 (Reuters) - Pampering ... [Published London South East - Aug 17 2014]
First reported Aug 11 2014 - Updated Aug 11 2014 - 1 reports

Computational Studies Support the Role of the C7-Sibirosamine Sugar of the Pyrrolobenzodiazepine (PBD) Sibiromycin in Transcription Factor Inhibition

The pyrrolo[2,1-c][1,4]benzodiazepines (PBDs) are a group of sequence-selective, DNA minor-groove binding agents that covalently attach to guanine residues. Originally derived from Streptomyces species, a number of naturally occurring PBD monomers exist ... [Published ACS Chemical Biology - Aug 11 2014]
Entities: DNA, Hydrogen, Molecule
First reported Aug 07 2014 - Updated Aug 07 2014 - 1 reports

Response Regulator Heterodimer Formation Controls a Key Stage in Streptomyces Development

by Mahmoud M. Al-Bassam, Maureen J. Bibb, Matthew J. Bush, Govind Chandra, Mark J. ButtnerThe orphan, atypical response regulators BldM and WhiI each play critical roles in Streptomyces differentiation. BldM is required for the formation of aerial hyphae, ... [Published Plosone.org - Aug 07 2014]
First reported Aug 07 2014 - Updated Aug 07 2014 - 1 reports

Findings from National Institutes of Health Broaden Understanding of Streptomyces (Structural and functional characterization of MppR, an...

Findings from National Institutes of Health Broaden Understanding of Streptomyces (Structural and functional characterization of MppR, an enduracididine biosynthetic enzyme from streptomyces hygroscopicus: functional diversity in the ...)By a News Reporter-Staff ... [Published HispanicBusiness.com - Aug 07 2014]
First reported Aug 05 2014 - Updated Aug 05 2014 - 1 reports

Methods for improving the tissue penetration of a drug by administering the drug together with a hyaluronidase protein

The present invention provides a tnaluronidase. The hyaiuronidase can be produced by the strain Streptomyces aitinocidm 77, Exemplary characteristics of the hyaluronidase include specific C-terminal or other amino acid sequences, including full-length ... [Published Free Patents Online - Aug 05 2014]

Quotes

...generates antibiotics," said Maria A Schumacher, Ph D , an associate professorprofessor of biochemistry at the Duke University School of Medicine. "Now we not only know that cyclic-di-GMP is responsible, but we also know exactly how it interacts with the protein BldD to activate its function."
...memories, but this finding appears to be unique," said Brennan, who is a professor and chair of biochemistry at Duke University School of Medicine. "We have never seen a type of structure before where two monomers become a functional dimer, with no direct interaction between them except a kind of small-molecule glue."
"We're looking for isolated populations of organisms. They will have evolved differently and therefore might produce new chemistry" Jaspars explains
...the time to look again," says Mervyn Bibb, a professor of molecular microbiology at JIC who collaborates with many other geneticists and chemists. "We need to think ecologically, which traditionally people haven't been doing."

More Content

All (33) | News (32) | Reports (0) | Blogs (1) | Audio/Video (0) | Fact Sheets (0) | Press Releases (0)
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FASEB MARC Program announces recipients of trav... [Published News-Medical.Net - 17 hours ago]
TGF-ß prevents self-reactive B cell activation [Published Health Canal - Aug 29 2014]
Developmental On-Off Switch Identified in Antib... [Published MedIndia - Aug 29 2014]
Small molecule acts as on-off switch for nature... [Published Infrosoft - Aug 29 2014]
Materials and methods for prevention and treatm... [Published PharmCast - Aug 29 2014]
Researchers try to make sure herpes does not fi... [Published Health Canal - Aug 28 2014]
Small Molecule Acts As On-Off Switch for Nature... [Published Health Canal - Aug 28 2014]
Small molecule acts as on-off switch for nature... [Published Bio-Medicine - Aug 28 2014]
Small molecule acts as on-off switch for nature... [Published EurekAlert! - Aug 28 2014]
Biotechnology: A new opium pipe [Published The Economist - Aug 28 2014]
RNA-Seq Analysis Reveals a Six-Gene SoxR Regulo... [Published Plosone.org - Aug 27 2014]
Don’t let bunch rots ruin your grapes [Published MSU Extension - Aug 27 2014]
6-Deoxy-13-hydroxy-8,11-dione-dihydrogranaticin... [Published Journal of Natural Products - Aug 26 2014]
Function and Evolution of Two Forms of SecDF Ho... [Published Plosone.org - Aug 21 2014]
Gentamicin, Neomycin, and Polymyxin B Bladder I... [Published U.S.Pharmacist - Aug 20 2014]
Caterpillar extract could one day save your life [Published Times Live South Africa - Aug 19 2014]
Extreme medicine: The search for new antibiotics [Published The Kuala Lumpur Post - Aug 18 2014]
INSIGHT-Extreme medicine: The search for new an... [Published London South East - Aug 17 2014]
Computational Studies Support the Role of the C... [Published ACS Chemical Biology - Aug 11 2014]
Response Regulator Heterodimer Formation Contro... [Published Plosone.org - Aug 07 2014]
Findings from National Institutes of Health Bro... [Published HispanicBusiness.com - Aug 07 2014]
Methods for improving the tissue penetration of... [Published Free Patents Online - Aug 05 2014]
Vaccine for the treatment of Mycobacterium rela... [Published PharmCast - Aug 01 2014]
Cyclic Hexapeptides from the Deep South China S... [Published Journal of Natural Products - Jul 29 2014]
Indimicins A–E, Bisindole Alkaloids from the D... [Published Journal of Natural Products - Jul 29 2014]
How the Human Body Cultivates Beneficial Bacteria [Published The Guardian Express - Jul 29 2014]
Bristol Myers Squibb : Patent Application Title... [Published 4 Traders - Jul 24 2014]
Variant CBH2 cellulases and related polynucleot... [Published Free Patents Online - Jul 22 2014]
George Armelagos [Published Telegraph - Jun 08 2014]
Tumor-initiating cells and methods of use [Published PharmCast - Apr 09 2014]
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Approach helps identify new biofuel sources that don't require farmland Washington DC (SPX) Feb 06, 2014 - While the debate over using crops for fuel continues, scientists are now reporting a new, fast approach to develop biofuel in a way that doesn't ...
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