Telaprevir

Type: Keyphrase
Name: Telaprevir
First reported Jul 31 2014 - Updated 19 hours ago - 2 reports

Hepatitis C Screening Beyond CDC Guidelines

World Health Organization. Hepatitis C. Wkly Epidemiol Rec 1997; 72: 65–9.World Health Organization. Hepatitis C – global prevalence (update). Wkly Epidemiol Rec 2000; 75: 18–9.Armstrong GL, Wasley A, Simard EP, et al. The prevalence of hepatitis C virus ... [Published General Medicine eJournal - 19 hours ago]
First reported Jul 31 2014 - Updated Jul 31 2014 - 1 reports

15 Deaths During Use Of Hep C Drug Telavic Since Japan Launch

Article # 28140730011Posted: Jul. 31, 2014 6:30 AM GMTExecutive SummaryOf the Japanese patients who have been prescribed the hepatitis C drug Telavic (telaprevir) since its launch in 2011, 23% have experienced severe side-effects such as dermatitis and ... [Published Health News Daily - Jul 31 2014]
First reported Jul 31 2014 - Updated Jul 31 2014 - 1 reports

Lack of Clinically Relevant Drug Interactions Between Elvitegravir plus Ritonavir Boosted-Atazanavir and Telaprevir

20th International AIDS ConferenceJuly 20-25, 2014Melbourne, Australia Reported by 20th International AIDS Conference, July 20-25, 2014, MelbourneJM Custodio, S Guo, EB Lawson, H Cao, A Silva, BP Kearney, and S Ramanathan Gilead Sciences, Inc., Foster ... [Published National AIDS Treatment Advocacy Project - Jul 31 2014]
First reported Jul 29 2014 - Updated Jul 29 2014 - 1 reports

New study identifies potential alternatives to Gilead’s Sovaldi

There are multiple hepatitis treatments in development that may serve as potential alternatives to Gilead Sciences’ (Nasdaq: GILD) Sovaldi (sofosbuvir), currently priced in the USA at $84,000 for 12 weeks of treatment - $1000 per pill, according to research ... [Published Pharma Letter - Jul 29 2014]
First reported Jul 29 2014 - Updated Jul 29 2014 - 1 reports

Hepatitis C Therapeutics Market - Global Industry Analysis, Trends and Forecast 2014 - 2020

Hepatitis is defined as the inflammation of the liver due to an infection by a virus or other causative organism or toxin. Hepatitis C on the other hand, is primarily as a result of the infection by hepatitis C virus (HCV). With a cure rate between 50%-80%, ... [Published MyNewsDesk - Jul 29 2014]
First reported Jul 28 2014 - Updated Jul 28 2014 - 2 reports

New therapies for HCV create better alternatives for patients

Therapeutic advances in treating hepatitis C virus have greatly increased a patient’s chance for a cure and at a faster rate, according to a consumer update from the FDA.The new report, available on the FDA website, states that interferon injections were ... [Published Orthopedics Today - Jul 28 2014]
First reported Jul 25 2014 - Updated Jul 25 2014 - 3 reports

The Hepatitis C virus is the main cause of liver transplant in the world

PORT OF SPAIN, Trinidad and TobagoPhoto - http://www2.prnewswire.com.br/imgs/pub/2014-07-25/original/2026.jpgClinical studies show that the regimen of the treatment based in Telaprevir together with pegylated interferon + ribavirin increases the percentage ... [Published Bio-Medicine - Jul 25 2014]
First reported Jul 22 2014 - Updated Jul 22 2014 - 1 reports

telaprevir (Incivek)

Pharmacy Author:Omudhome Ogbru, PharmDDr. Ogbru received his Doctorate in Pharmacy from the University of the Pacific School of Pharmacy in 1995. He completed a Pharmacy Practice Residency at the University of Arizona/University Medical Center in 1996. ... [Published MedicineNet.com - Jul 22 2014]
First reported Jul 16 2014 - Updated Jul 16 2014 - 1 reports

Researchers from Pfizer Report on Findings in Antiretrovirals (The Effects of Boceprevir and Telaprevir on the Pharmacokinetics of Maraviroc: An...

Researchers from Pfizer Report on Findings in Antiretrovirals (The Effects of Boceprevir and Telaprevir on the Pharmacokinetics of Maraviroc: An Open-Label, Fixed-Sequence Study in Healthy Volunteers )By a News Reporter-Staff News Editor at Biotech Week ... [Published 4 Traders - Jul 16 2014]
First reported Jul 14 2014 - Updated Jul 14 2014 - 1 reports

A Pill for HCV -- Myth or Foreseeable Future?

Lavanchy D. Evolving epidemiology of hepatitis C virus. Clin Microbiol Infect 2011; 17: 107–15.Negro F, Alberti A. The global health burden of hepatitis C virus infection. Liver Int 2011; 31(Suppl. 2): 1–3.Cornberg M, Razavi HA, Alberti A, et al. A systematic ... [Published Diabetes Care - Jul 14 2014]
First reported Jun 25 2014 - Updated Jun 25 2014 - 2 reports

Janssen calls on governments to tackle hepatitis C

Governments around the world need to do more to address hepatitis C, according to a report backed by pharma company Janssen.The report, Tackling hepatitis C: Moving towards an integrated policy approachInstead, it has been non-government organisations ... [Published PMLive - Jun 25 2014]
First reported Apr 28 2014 - Updated Apr 28 2014 - 2 reports

Treatment of HCV with ABT-450/r–Ombitasvir and Dasabuvir with Ribavirin

Approximately 184 million people worldwide have chronic hepatitis C virus (HCV) infection, and more than 350,000 people die of HCV-related liver disease each year.1,2 Until recently, the standard of care for chronic HCV genotype 1 infection was a first-generation ... [Published NEJM Articles Most Widely Covered in the Press - Apr 28 2014]

Quotes

The key element of the new regimens is that they do not use interferon, "which does have delivery issues as well as adverse effects" Majumdar told MedPage Today
"The efficacy and safety of 24 weeks of daclatasvir plus asunaprevir represents a huge improvement on the first generation of protease inhibitor-based triple therapies for HCV genotype 1b infection (up to 48 weeks of boceprevir or telaprevir in combination with PEG/RBV)."
Writing in a linked Comment, Professor Ed Gane, Director of the New Zealand Liver Transplant Unit at Auckland City Hospital in New Zealand says, "In the future, very-short-duration, all-oral DAA regimens should improve treatment uptake and success, and reduce the health burden from liver-related complications. When combined with targeted testing and treatment of populations who transmit infection (ie, treatment as prevention), these DAA regimens might eventually eliminate HCV infection. The only barrier to achieving this goal will be the ability to access these new therapies. In many developing countries where HCV is endemic, interferon-based therapy will remain the first choice because of the high cost of DAAs and lack of reimbursement. As almost 75% of all patients with HCV infection reside in economically deprived regions of eastern Europe, Asia, and the Middle East, consideration should be given to discounting prices in these regions.29 Eradication of HCV infection worldwide will only be achievable through universal access to HCV testing and new DAA regimens." HCV genotypes 1a and 1b are the most common, accounting for about 60% of global infections http://www.who.int/mediacentre/factsheets/fs164/en/
"This is the greatest pharmaceutical launch in history," said Michael Yee, an analyst at RBC Capital Markets. "It's doing sales in the first year what some drugs like Lipitor would do after 10 years. It's amazing."

More Content

All (49) | News (36) | Reports (0) | Blogs (11) | Audio/Video (0) | Fact Sheets (1) | Press Releases (0)
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Hepatitis C Screening Beyond CDC Guidelines [Published General Medicine eJournal - 19 hours ago]
15 Deaths During Use Of Hep C Drug Telavic Sinc... [Published Health News Daily - Jul 31 2014]
Preventing Mortality in Patients With Cirrhosis... [Published Diabetes Care - Jul 31 2014]
Lack of Clinically Relevant Drug Interactions B... [Published National AIDS Treatment Advocacy Project - Jul 31 2014]
New study identifies potential alternatives to ... [Published Pharma Letter - Jul 29 2014]
Hepatitis C Therapeutics Market - Global Indust... [Published MyNewsDesk - Jul 29 2014]
Hepatitis C Therapy in Elderly Patients [Published Diabetes Care - Jul 29 2014]
3D Hepatitis C Combo Effective in HIV Patients [Published EverydayHealth.com - Jul 29 2014]
New therapies for HCV create better alternative... [Published Orthopedics Today - Jul 28 2014]
New pills can help cure hepatitis C [Published The Freepress Journal - Jul 28 2014]
Medical News Today: Studies reveal success of n... [Published Medical News Today - Jul 28 2014]
The Lancet: New oral drug regimens cure hardest... [Published EurekAlert! - Jul 27 2014]
NHS England's Sovaldi fund: opening the floodga... [Published Pharmafocus - Jul 27 2014]
The Hepatitis C virus is the main cause of live... [Published Bio-Medicine - Jul 25 2014]
The Hepatitis C virus is the main cause of live... [Published BioPortfolio - Jul 25 2014]
The Hepatitis C virus is the main cause of live... [Published PR Newswire: General Business - Jul 25 2014]
Gilead pill reaches $3.48B in quarterly sales [Published San Francisco Chronicle - Jul 24 2014]
telaprevir (Incivek) [Published MedicineNet.com - Jul 22 2014]
Costly hepatitis C drugs could add $300 to ever... [Published San Francisco Chronicle - Jul 21 2014]
boceprevir (Victrelis) [Published MedicineNet.com - Jul 19 2014]
Hepatitis C high among baby boomers [Published Craig Daily Press - Jul 18 2014]
Researchers from Pfizer Report on Findings in A... [Published 4 Traders - Jul 16 2014]
Olysio leads charge at J&J but competition is o... [Published PMLive - Jul 16 2014]
Dolutegravir: A Next-Generation Integrase Inhib... [Published National AIDS Treatment Advocacy Project - Jul 14 2014]
A Pill for HCV -- Myth or Foreseeable Future? [Published Diabetes Care - Jul 14 2014]
Entry inhibitors, DAA synergistically inhibited... [Published Orthopedics Today - Jul 11 2014]
Factors Influencing Adherence in Hep-C Infected... [Published General Medicine eJournal - Jul 11 2014]
Survey Finds Most Primary Care Providers Unawar... [Published HIV and Hepatitis.com - Jul 10 2014]
Effectiveness, Costs Weigh on HCV Treatment Dec... [Published ASHP - Jun 30 2014]
Sovaldi, the $1,000 pill [Published Pharmaceutical Commerce - Jun 25 2014]
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The Hepatitis C virus is the main cause of live... [Published PR Newswire: General Business - Jul 25 2014]
PORT OF SPAIN, Trinidad and Tobago, July 25, 2014 /PRNewswire/ -- The Chemistry, Food & Drugs Division of the Trinidad & Tobago Ministry of Health approved the introduction of Telaprevir to the market, an innovative therapy that significantly increases ...
Treating Hepatitis C: Criticisms of sofosbuvir [Published The Incidental Economist (Posts) - Jun 17 2014]
The following is part of a series of guest posts on hepatitis C by Allan Joseph, a medical student at the Warren Alpert Medical School of Brown University and TIE research assistant. You can follow Allan on Twitter:  @allanmjoseph . Links to all posts ...
Treating Hepatitis C: Sofosbuvir [Published The Incidental Economist (Posts) - Jun 16 2014]
The following is part of a series of guest posts on hepatitis C by Allan Joseph, a medical student at the Warren Alpert Medical School of Brown University and TIE research assistant. You can follow Allan on Twitter:  @allanmjoseph . Links to all posts ...
Treating hepatitis C: Treatment options before ... [Published The Incidental Economist (Posts) - Jun 13 2014]
The following is part of a series of guest posts on hepatitis C by Allan Joseph, a medical student at the Warren Alpert Medical School of Brown University and TIE research assistant. You can follow Allan on Twitter:  @allanmjoseph . Links to all posts ...
Treatment of HCV with ABT-450/r–Ombitasvir and ... [Published NEJM Articles Most Widely Covered in the Press - Apr 28 2014]
Approximately 184 million people worldwide have chronic hepatitis C virus (HCV) infection, and more than 350,000 people die of HCV-related liver disease each year.1,2 Until recently, the standard of care for chronic HCV genotype 1 infection was a first-generation ...
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