Thioridazine

Type: Keyphrase

Name: Thioridazine

First reported May 18 2013 - Updated May 18 2013 - 1 reports

Why does old schizophrenia medicine work on antibiotics-resistant bacteria?

Home » Blogs » In 2008, researchers from the University of Southern Denmark showed that the drug thioridazine, which has previously been used to treat schizophrenia, is also a powerful weapon against antibiotic-resistant bacteria such as staphylococci ... [Published BioPortfolio - May 18 2013]

Entities: Bacteria, Thioridazine, Biotechnology, University of Southern Denmark

First reported May 18 2013 - Updated May 18 2013 - 1 reports

Thioridazine works by weakening staphylococcal cell wall, new study reveals

In 2008 researchers from the University of Southern Denmark showed that the drug thioridazine, which has previously been used to treat schizophrenia, is also a powerful weapon against antibiotic-resistant bacteria such as staphylococci (Staphylococcus ... [Published News-Medical.Net - May 18 2013]

Entities: Thioridazine, Bacteria, University of Southern Denmark, Antibiotic

First reported May 18 2013 - Updated May 18 2013 - 1 reports

Now We Know Why Old Scizophrenia Medicine Works on Antibiotics-resistant Bacteria

Entities: Bacteria, Thioridazine, University of Southern Denmark, Staphylococcus Aureus, Antibiotic-Resistant

First reported Dec 22 2012 - Updated Dec 22 2012 - 1 reports

Mylan Incorporated

THIORIDAZINE HYDROCHLORIDEtablet, Film Coated [Mylan Pharmaceuticals Inc.]

Updated Date: Dec 20, 2012 EST ... [Published DailyMed Drug Label Updates for the last seven ... - Dec 22 2012]

Entities: Thioridazine, Mylan Incorporated

First reported Dec 20 2012 - Updated Dec 20 2012 - 1 reports

THIORIDAZINE HYDROCHLORIDEtablet, Film Coated [Mylan Pharmaceuticals Inc.]

Updated Date: Dec 20, 2012 EST ... [Published DailyMed Drug Label Updates for the last seven ... - Dec 20 2012]

Entities: Thioridazine, Mylan Incorporated

Quotes

"When we treat the bacteria with antibiotics alone, nothing happens - the bacteria are not even affected. But when we add both thioridazine and antibiotics, something happens: thioridazine weakens the bacterial cell wall by removing glycine (an amino acid) from the cell wallwall In the absence of glycine, the antibiotics can attack the weakened cell wall and kill staphylococcus bacteria" , explains Janne Kudsk Klitgaard, visiting scholar at the Department of Biochemistry and Molecular Biology, University of Southern Denmark

Thioridazine works by weakening staphylococcal cell wall, new study reveals [Published News-Medical.Net - May 18 2013]

"Now that we know how thioridazine works, we can develop drugs that target the resistant bacteria. And just as important: We can remove or inactivate the parts of thioridazine, which treats schizophrenia, so we end up with a brand new product that is no longer an antipsychotic, "explains Janne Kudsk Klitgaard."

Now we know why old scizophrenia medicine works on antibiotics-resistant bacteria [Published Medical Xpress - May 17 2013]

"The pooled analyses represent an important body of evidence supporting MYRBETRIQ as a potential treatment option for OAB symptoms of urge urinary incontinence, urgency and urinary frequency" said Shontelle Dodson, PharmD, Senior Director, Astellas Scientific and Medical Affairs

Data on MYRBETRIQ® (mirabegron) as Treatment for Overactive Bladder Presented at AUA 2013 [Published OSIX News - May 07 2013]

...Transit was delayed in ten of these eleven subjects. The authors observed: "when there was delayed esophageal transit of tablets, the initial absorption of acetaminophen (measured as AUC over the first 60 min) was lower than that after normal esophageal transit of tablets. The peak plasma acetaminophen concentration was also lower and occurred 90 min later when transit was delayed. These kinetic changes decrease the effectiveness of acetaminophen as an analgesic." See K S Channer and C J Roberts, "Effect of Delayed Esophageal Transit on Acetaminophen Absorption" Clinical Pharmacology and Therapeutics 37, 72-76...

Solid dosage form that promotes reliable oral, esophageal and GI transit [Published PharmCast - Mar 14 2013]

More Content

sort by: Date \| Relevance
Why does old schizophrenia medicine work on ant... [Published BioPortfolio - May 18 2013]
Thioridazine works by weakening staphylococcal ... [Published News-Medical.Net - May 18 2013]
Now We Know Why Old Scizophrenia Medicine Works... [Published ScienceNewsline - May 18 2013]
Now we know why old scizophrenia medicine works... [Published Medical Xpress - May 17 2013]
Astellas Pharma US Release: Data on MYRBETRIQ??... [Published BioSpace - May 08 2013]
Data on MYRBETRIQ® (mirabegron) as Treatment fo... [Published OSIX News - May 07 2013]
Data on MYRBETRIQ (mirabegron) as Treatment for... [Published FinanzNachrichten.de - May 07 2013]
Ben Seewald: From Brain Tumour Patient to Cross... [Published Huffington Post Canada - Apr 30 2013]
Drugs - oxymorphone - usage, dosage, interacti... [Published AARP - Segunda Juventud - Apr 15 2013]
Par Pharma starts shipping of fluvoxamine malea... [Published PharmaBiz - Mar 16 2013]
Solid dosage form that promotes reliable oral, ... [Published PharmCast - Mar 14 2013]
AlignLife Nutraceuticals Secures Advanced Form ... [Published PRWeb - Feb 11 2013]
THIORIDAZINE HYDROCHLORIDEtablet, Film Coated [... [Published DailyMed Drug Label Updates for the last seven ... - Dec 22 2012]
THIORIDAZINE HYDROCHLORIDEtablet, Film Coated [... [Published DailyMed Drug Label Updates for the last seven ... - Dec 20 2012]
Catecholamine receptor modulation [Published PharmCast - Aug 31 2012]