Tyler Jacks

Type: Person
Name: Tyler Jacks
First reported Aug 21 2014 - Updated Aug 21 2014 - 1 reports

Where the Charles meets the Potomac: Inside MIT's Washington Office

As director of  MIT’s Washington Office , William Bonvillian spends more time in the halls of federal buildings than in the Infinite Corridor. And if you’re wondering why MIT has an office in the nation’s capital, you’re not alone: Bonvillian says that’s ... [Published MIT News feed - Aug 21 2014]
First reported Aug 19 2014 - Updated Aug 19 2014 - 1 reports

RNA combination therapy for lung cancer offers promise for personalized medicine

However, delivering these small RNAs to solid tumors remains a significant challenge, as the RNAs must target the correct cells and avoid being broken down by enzymes in the body. To date, most work in this area has focused on delivery to the liver, where ... [Published HispanicBusiness.com - Aug 19 2014]
First reported Aug 14 2014 - Updated Aug 15 2014 - 4 reports

Research offers promise for personalized RNA combination therapies to treat lung cancer

Researchers develop new lung-on-chip model for laboratory studies of respiratory challengesYoung inner-city children appear to suffer from food allergiesMedical advisory panel recommends new pneumonia vaccine for seniorsNew therapeutic strategy to combat ... [Published News-Medical.Net - Aug 15 2014]
First reported Aug 14 2014 - Updated Aug 15 2014 - 1 reports

A new way to model cancer

By a News Reporter-Staff News Editor at Cancer Weekly -- CAMBRIDGE, MA - Sequencing the genomes of tumor cells has revealed thousands of mutations associated with cancer. One way to discover the role of these mutations is to breed a strain of mice that ... [Published HispanicBusiness.com - Aug 14 2014]
First reported Aug 12 2014 - Updated Aug 12 2014 - 1 reports

Small RNA therapy for lung cancer [Genetics]

Wen Xue a , b , c , 1 , James E. Dahlman a , d , 1 , Tuomas Tammela a , b , c , Omar F. Khan a , e , Sabina Sood a , b , c , Apeksha Dave a , b , Wenxin Cai a , b , c , Leilani M. Chirino a , b , c , Gillian R. Yang a , b , Roderick Bronson f ... [Published PNAS - Aug 12 2014]
Entities: RNA, Tumor, sirna, Lung Cancer
First reported Aug 07 2014 - Updated Aug 07 2014 - 1 reports

T2 Biosystems Sputters Through IPO Queue, Raises $57M

If the question was how a diagnostics company would fare in a sputtering IPO market, the answer for T2 Biosystems was: not too well.The Lexington, MA-based company priced well below its projected range, raising about $57.2 million before paying its underwriters. ... [Published Xconomy - Aug 07 2014]
First reported Aug 06 2014 - Updated Aug 07 2014 - 3 reports

CRISPR Used to Create Mouse Models of Cancer

When scientists study the genetics of cancer , they often breed mice strains that carry selected cancer-associated mutations. But cultivating such strains, usually via transgenesis or gene targeting in embryonic stem cells, is often time-consuming and ... [Published Genetic Engineering News - Aug 07 2014]
First reported Mar 30 2014 - Updated Mar 31 2014 - 1 reports

Erasing a genetic mutation

Using a new gene-editing system based on bacterial proteins, MIT researchers have cured mice of a rare liver disorder caused by a single genetic mutation. The findings, described in the March 30 issue of Nature Biotechnology, offer the first evidence ... [Published MIT News feed - Mar 30 2014]
First reported Mar 13 2014 - Updated Mar 13 2014 - 1 reports

New view of tumors’ evolution

Cancer cells undergo extensive genetic alterations as they grow and spread through the body. Some of these mutations, known as “drivers,” help spur cells to grow out of control, while others (“passengers”) are merely along for the ride.MIT cancer biologists ... [Published MIT News feed - Mar 13 2014]

Quotes

"Small-RNA therapy holds great promise for cancer," Jacks says. "it is widely appreciated that the major hurdle in this field is efficient delivery to solid tumors outside of the liver, and this work goes a long way in showing that this is achievable."
...the process, which requires introducing mutations into embryonic stem cells, can take more than a year and costs hundreds of thousands of dollars. "it's a very long process, and the more genes you're working with, the longer and more complicated it becomes" Jacks says

More Content

All (14) | News (9) | Reports (0) | Blogs (5) | Audio/Video (0) | Fact Sheets (0) | Press Releases (0)
sort by: Date | Relevance
Where the Charles meets the Potomac: Inside MIT... [Published MIT News feed - Aug 21 2014]
RNA combination therapy for lung cancer offers ... [Published HispanicBusiness.com - Aug 19 2014]
Research offers promise for personalized RNA co... [Published News-Medical.Net - Aug 15 2014]
RNA combination therapy for lung cancer offers ... [Published Noodls - Aug 15 2014]
RNA Combination Therapy for Lung Cancer Offers ... [Published Newswise - Aug 14 2014]
RNA combination therapy for lung cancer offers ... [Published MIT News feed - Aug 14 2014]
A new way to model cancer [Published HispanicBusiness.com - Aug 14 2014]
Small RNA therapy for lung cancer [Genetics] [Published PNAS - Aug 12 2014]
CRISPR Used to Create Mouse Models of Cancer [Published Genetic Engineering News - Aug 07 2014]
T2 Biosystems Sputters Through IPO Queue, Raise... [Published Xconomy - Aug 07 2014]
A new way to model cancer [Published Bio-Medicine - Aug 06 2014]
A new way to model cancer [Published MIT News feed - Aug 06 2014]
Erasing a genetic mutation [Published MIT News feed - Mar 30 2014]
New view of tumors’ evolution [Published MIT News feed - Mar 13 2014]
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sort by: Date | Relevance
Where the Charles meets the Potomac: Inside MIT... [Published MIT News feed - Aug 21 2014]
As director of  MIT’s Washington Office , William Bonvillian spends more time in the halls of federal buildings than in the Infinite Corridor. And if you’re wondering why MIT has an office in the nation’s capital, you’re not alone: Bonvillian says that’s ...
RNA combination therapy for lung cancer offers ... [Published MIT News feed - Aug 14 2014]
Small RNA molecules, including microRNAs (miRNAs) and small interfering RNAs (siRNAs), offer tremendous potential as new therapeutic agents to inhibit cancer-cell growth. However, delivering these small RNAs to solid tumors remains a significant challenge, ...
A new way to model cancer [Published MIT News feed - Aug 06 2014]
Sequencing the genomes of tumor cells has revealed thousands of mutations associated with cancer. One way to discover the role of these mutations is to breed a strain of mice that carry the genetic flaw — but breeding such mice is an expensive, time-consuming ...
Erasing a genetic mutation [Published MIT News feed - Mar 30 2014]
Using a new gene-editing system based on bacterial proteins, MIT researchers have cured mice of a rare liver disorder caused by a single genetic mutation. The findings, described in the March 30 issue of Nature Biotechnology, offer the first evidence ...
New view of tumors’ evolution [Published MIT News feed - Mar 13 2014]
Cancer cells undergo extensive genetic alterations as they grow and spread through the body. Some of these mutations, known as “drivers,” help spur cells to grow out of control, while others (“passengers”) are merely along for the ride.MIT cancer biologists ...
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