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"p38 MAP kinase is implicated in stress response, and when activated by hypoxia, it phosphorylates and activates the kinase MK2, which then phosphorylates the small heat shock protein HSP27 leading to actin filament formation in endothelial cells (An et al., Am. J Physiol. Cell. Physiol., 2005, 289, C521-530; and Kayyali et al., J Biol. Chem., 2002, 277, 42596-42602). Unphosphorylated HSP27 binds actin and blocks its polymerization, and has been associated with decreased actin stress fibers and decreased focal adhesions (Schneider et al., J Cell . Physiol., 1998, 177, 575-584)."

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Researchers Submit Patent Application, "Composi... [Published HispanicBusiness.com - Sep 25 2014]
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When You Learn You Have High Blood Pressure [Published PR Web via Yahoo! - Sep 16 2014]
Merck's Mantra On Focus Precludes An Inversion ... [Published Forbes.com - Sep 15 2014]
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VASOTEC (Enalapril Maleate) Tablet VASOTEC (Ena... [Published DailyMed Drug Label Updates for the last seven ... - May 02 2014]
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