Zinc Finger

Type: Keyphrase
Name: Zinc Finger
First reported Sep 12 2014 - Updated Sep 12 2014 - 1 reports

4 Reasons Sangamo Biosciences Is Positioned For A Run-Up

By R.S. Analytics :Sangamo BioSciences (NASDAQ: SGMO ) is a clinical stage biopharmaceutical company focusing on the research, development, and commercialization of ZFPs (zinc finger DNA -binding proteins) for gene regulation and gene modification. Sangamo, ... [Published BioPortfolio - Sep 12 2014]
First reported Sep 10 2014 - Updated Sep 10 2014 - 1 reports

Sangamo Biosciences, Inc. Is Preparing To Drop Big

Investors may only notice a big move after it has occurred. The tendency is to then try to jump on board, only to find out that they missed the boat as the stock breaks back down.Wouldn’t it be nice to recognize a big move before its over?That’s where ... [Published Benzinga.com - Sep 10 2014]
First reported Sep 10 2014 - Updated Sep 10 2014 - 1 reports

Sangamo Biosciences Trading 6.3% Higher Following Analyst Upgrade (SGMO)

Sangamo Biosciences (NASDAQ:SGMO) shot up 6.3% during trading on Wednesday after Wedbush raised their price target on the stock from $27.00 to $28.00, Analyst Ratings.Net reports. The company traded as high as $13.10 and last traded at $12.92, with a ... [Published American Banking News - Forex - Sep 10 2014]
First reported Sep 10 2014 - Updated Sep 10 2014 - 1 reports

Sangamo Biosciences' (SGMO) CEO Edward Lanphier Presents at Morgan Stanley Healthcare Conference (Transcript)

Matthew Palmer - Morgan StanleyGood morning and welcome to the Morgan Stanley Global Healthcare Conference. My name is Matthew Palmer and I am a member of the Biotechnology Equity Research team here at Morgan Stanley. Just before I get started we need ... [Published Seeking Alpha - Sep 10 2014]
First reported Sep 10 2014 - Updated Sep 10 2014 - 1 reports

Sector Update: Health-Care Shares Mixed Ahead of Opening Bell

PFE: flatABT: flatMRK: +0.40%AMGN: flatHealth-care shares were mixed in pre-market trade Wednesday.In health-care stocks news, Sangamo BioSciences ( SGMO ) is planning to submit an Investigational New Drug ( IND ) application for the treatment of hemophilia ... [Published Nasdaq - Sep 10 2014]
Entities: Healthcare, Arixtra, Stocks
First reported Sep 10 2014 - Updated Sep 10 2014 - 1 reports

Sangamo IND for hemophilia B slated for Q2 2015

News EditorSangamo Biosciences (NASDAQ:SGMO) says its plans to submit an IND to the FDA for the treatment of hemophilia B based on its zinc finger nuclease (ZFN)-mediated In Vivo Protein Replacement Platform (IVPRP). It will be the first therapeutic application ... [Published Seeking Alpha - Sep 10 2014]
First reported Sep 10 2014 - Updated Sep 10 2014 - 1 reports

Sangamo BioSciences Announces Target Date For First IND For Sangamo's In Vivo ZFN Genome-Editing Platform For Monogenic Diseases

"Shire has been impressed by the rapid progress of the novel hemophilia B program developed by Sangamo," said Albert Seymour"Sangamo's research and development team has succeeded in rapidly advancing the hemophilia B program through small and large animal ... [Published Pettinga Financial Advisors - Sep 10 2014]
First reported Sep 03 2014 - Updated Sep 03 2014 - 1 reports

HIV Research to Look Forward to at ICAAC 2014

There's another HIV conference right around the corner, the 54th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC 2014), which will be held in Washington, D.C., from Sept. 5-9.While ICAAC covers a range of infectious diseases, there ... [Published The Body - Sep 03 2014]
First reported Aug 28 2014 - Updated Aug 28 2014 - 1 reports

Top Ten BioTechniques Genome Editing Articles

Genome editing has always been a popular topic among biological researchers, but interest has only increased with the development of new technologies such as CRISPR/Cas9, TALENs, and Zinc Finger... ... [Published Bio Techniques - Aug 28 2014]
Entities: Genome, Zinc Finger
First reported Aug 20 2014 - Updated Aug 20 2014 - 1 reports

Brainiac Superhero science

Superheroes are capable of preposterous feats: They leap tall buildings in a single bound and battle hordes of oversized enemies into the ground. Even if their actions are beyond belief, they typically have a backstory that makes them at least thinly ... [Published Boston Globe - Aug 20 2014]
First reported Aug 19 2014 - Updated Aug 19 2014 - 1 reports

Sigma-Aldrich launches 'knock-out' way to create liver toxicity assays

Sigma-Aldrich has teamed with Biopredic to produce genetically-modified human liver cell lines and assays it says can cut costs by reducing animal toxicology studies in drug discovery.Sigma-Aldrich Life Science intends to use its own CompoZr Zinc Finger ... [Published Outsourcing Pharma - Aug 19 2014]
First reported Aug 12 2014 - Updated Aug 12 2014 - 1 reports

Engineered landing pads for gene targeting in plants

A method for producing a transgenic plant includes providing a nucleic acid molecule comprising at least two regions of nucleic acid sequence that lack sequence homology with genomic DNA of the plant cell, and at least two zinc finger nuclease recognition ... [Published Free Patents Online - Aug 12 2014]

Quotes

Development partner Shire (NASDAQ:SHPG) Research Chief Albert Seymour, Ph D , says, "Shire has been impressed by the rapid progress of the novel hemophilia B program developed by Sangamo. The Shire team continues to work very closely with Sangamo to submit the IND package to support this program."
"Shire has been impressed by the rapid progress of the novel hemophilia B program developed by Sangamo" said Albert Seymour
"Because this approach is only going after viral genes, there should be no off-target effects on normal cells," said Dr. Cullen. "You can think of this as targeting a missile that will destroy a certain target. You put in a code that tells the missile exactly what to hit, and it will only hit that, and it will not hit anything else because it does not have the code for another target."
...Gerd A Blobel, M D , Ph D , who holds the Frank E Weise III Endowed Chair in Pediatric Hematology at The Children's Hospital of Philadelphia. "If we can translate this approach into the clinic, this may become a new treatment for patients with sickle-cell disease."

More Content

All (55) | News (43) | Reports (0) | Blogs (11) | Audio/Video (0) | Fact Sheets (0) | Press Releases (1)
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ALDH1A1 Maintains Ovarian Cancer Stem Cell-Like... [Published Plosone.org - Sep 13 2014]
Restored immunosuppressive effect of mesenchyma... [Published Arthritis & Rheumatism - Sep 12 2014]
CRISPR Gene Editing—Poised to Revolutionize Neu... [Published Alzheimer Research Forum - Sep 12 2014]
BioSpotlight / Citations [Published Bio Techniques - Sep 12 2014]
4 Reasons Sangamo Biosciences Is Positioned For... [Published BioPortfolio - Sep 12 2014]
4 Reasons Sangamo Biosciences Is Positioned For... [Published Seeking Alpha - Sep 12 2014]
Unkempt Is Negatively Regulated by mTOR and Unc... [Published Plosone.org - Sep 12 2014]
Sangamo Biosciences, Inc. Is Preparing To Drop Big [Published Benzinga.com - Sep 10 2014]
Sangamo Biosciences Trading 6.3% Higher Follow... [Published American Banking News - Forex - Sep 10 2014]
Sangamo Biosciences' (SGMO) CEO Edward Lanphier... [Published Seeking Alpha - Sep 10 2014]
Sector Update: Health-Care Shares Mixed Ahead o... [Published Nasdaq - Sep 10 2014]
Sangamo IND for hemophilia B slated for Q2 2015 [Published Seeking Alpha - Sep 10 2014]
Sangamo BioSciences Announces Target Date For F... [Published Pettinga Financial Advisors - Sep 10 2014]
Transcriptome/Degradome-Wide Discovery of Micro... [Published Plosone.org - Sep 09 2014]
New Genomic Editing Methods Produce Better Dise... [Published Prlog - Sep 08 2014]
Strategies to Eliminate HBV Infection [Published General Medicine eJournal - Sep 04 2014]
HIV Research to Look Forward to at ICAAC 2014 [Published The Body - Sep 03 2014]
A Long Line of LINEs [Published The Scientist - Sep 01 2014]
Top Ten BioTechniques Genome Editing Articles [Published Bio Techniques - Aug 28 2014]
Nuclear Glycolytic Enzyme Enolase of Toxoplasma... [Published Plosone.org - Aug 25 2014]
8/22/2014 Researchers Identify New Genetic Risk... [Published Neurology Today - Aug 22 2014]
Of Gene Drives and Jurassic Park [Published Bio Techniques - Aug 21 2014]
The effects of sonic hedgehog signaling pathway... [Published 7thSpace - Aug 21 2014]
Brainiac Superhero science [Published Boston Globe - Aug 20 2014]
Sigma-Aldrich launches 'knock-out' way to creat... [Published Outsourcing Pharma - Aug 19 2014]
Dysregulated transcriptional and post-translati... [Published 7thSpace - Aug 19 2014]
Gene Therapy Reactivates Cell Death Pathways in... [Published Biotech Daily - Aug 18 2014]
Forcing chromosomes into loops may switch off s... [Published EurekAlert! - Aug 14 2014]
How Did The Hulk Become The Hulk? Science Final... [Published Recode - Aug 14 2014]
Reduction in C-terminal amidated species of rec... [Published BMC - Aug 14 2014]
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Blogs

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An easier way to manipulate malaria genes [Published MIT News feed - Aug 10 2014]
Plasmodium falciparum, the parasite that causes malaria, has proven notoriously resistant to scientists’ efforts to study its genetics. It can take up to a year to determine the function of a single gene, which has slowed efforts to develop new, more ...
Interplay of TRIM28 and DNA methylation in cont... [Published Genome Research current issue - Aug 01 2014]
Reverse transcription-derived sequences account for at least half of the human genome. Although these retroelements are formidable motors of evolution, they can occasionally cause disease, and accordingly are inactivated during early embryogenesis through ...
How DNA Scissors Can Perform Surgery Directly O... [Published Popular Science - New Technology, Science News, ... - Jul 09 2014]
New molecules that chop up DNA may fight deadly diseases.Stew Dean via Flickr CC Jay Johnson’s DNA was cut into pieces. Tiny molecular scissors chopped it into slices the cell couldn’t readily repair. The cell did its best at a speedy patch-up job, ...
A Method of Destroying Only Damaged Mitochondri... [Published Fight Aging! - Jun 03 2014]
Mitochondrial DNA (mtDNA) damage is an important cause of degenerative aging. Via a complicated chain of events it leads to a small population of malfunctioning cells overtaken by malfunctioning mitochondria that export harmful reactive compounds ...
Sangamo gets CIRM fund to support clinical tria... [Published PBR - News - Jun 02 2014]
Sangamo BioSciences (SGMO) has announced that the California Institute for Regenerative Medicine (CIRM) has granted a $5.6 million Strategic Partnership Award to fund clinical studies at City of Hope to develop a potentially curative ZFP Therapeutic for ...
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Press Releases

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Sigma® Life Science Launching Genetically-Modif... [Published PR Newswire - Jan 17 2014]
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